2/13/12 ... A literature review of the efficacy of routine follow-up CT scans of the head after complicated mild traumatic brain injury (TBI).
2/17/12 ... Minor traumatic brain injury is a common injury with variable clinical presentation. The system of diagnosis used in this case found a significant relationship between the clinical assessment and imaging results.
3/27/2012 ... It is crucial that a clinically useful evaluation and management procedure be instituted for MTBI that encompasses both molecular pathophysiology and functional outcome.
3/5/2012 ... A powerful new imaging technique called High Definition Fiber Tracking (HDFT) will allow doctors to clearly see for the first time neural connections broken by traumatic brain injury (TBI).
3/14/2012 ... The FOUR score is an accurate predictor of outcome in TBI patients. It has some advantages over GCS, such as all components of FOUR score but not GCS can be rated in intubated patients.
3/22/2012 ... Radiologic findings during the first month were significantly associated with the long-term outcome. Especially, basal ganglia lesions were associated with a poor outcome.
Identifying factors associated with perceived success in the transition from hospital to home after brain injury
4/10/2012 ... A combination of sentinel events and personal and environmental factors influences the perceptions of individuals and their families regarding the success of the transition from hospital to home.
4/16/2012 ... This study shows that olfactory deficits may be indicative of affect recognition impairments and reduced empathy.
4/16/2012 ... This study shows that olfactory deficits may be indicative of affect recognition impairments and reduced empathy.
A review of magnetic resonance imaging and diffusion tensor imaging findings in mild traumatic brain injury
4/26/2012 ... We believe that the enhanced sensitivity of newer and more advanced
neuroimaging techniques for identifying areas of brain damage in mTBI will be
important for documenting the biological basis of postconcussive symptoms, which
are likely associated with subtle brain alterations, alterations that have
heretofore gone undetected due to the lack of sensitivity of earlier neuroimaging
Identification and validation of prognostic criteria for persistence of mild traumatic brain injury-related impairment in the pediatric patient
7/26/2012 ... This is the first study demonstrating prognostic criteria that may greatly help physicians identify patients who would benefit from structured follow-up care after MTBI.
7/27/2012 ... The authors
conclude that fMRI in combination with related methods can be expected to play an increasing role in research related to studies of pathophysiological mechanisms of the sequelae of mTBI as well as in diagnosis and treatment monitoring.
8/6/2012 ... The findings demonstrate the potential of robotic assessments for identifying deficits in visuomotor control and position sense following TBI. Improved identification of neurologic impairments following TBI may ultimately enhance rehabilitation.
8/10/2012 ... PTA duration is a valuable predictor of intelligence impairment following TBI. Results support the routine assessment of PTA duration in clinical settings.
8/15/2012 ... Neurogenic and psychogenic postconcussion symptoms were identified
at the acute-phase postinjury. Findings suggest that treating persons with mTBI as a homogenous sample is not prudent.
8/21/2012 ... Meta-analysis revealed the posterior part of the CC was more vulnerable to mTBI compared with the anterior part, and suggested the potential utility of DTI to detect white matter damage in the CC of mTBI patients.
8/28/2012 ... Significant deterioration of performance in the distraction setting was observed among clients with mTBI.
9/12/2012 ... Patients who suffer milder forms of TBI should also be considered for endocrine evaluation if they exhibit any clinical features of pituitary hormone deficiencies.
Neurogenic and psychogenic acute postconcussion symptoms can be identified after mild traumatic brain injury
9/14/2012 ... Neurogenic and psychogenic postconcussion symptoms were identified at the acute-phase postinjury. Findings suggest that treating persons with mTBI as a homogenous sample is not prudent.
9/28/2012 ... This study compares inter-rater-reliability, lesion detection and
clinical relevance of T2-weighted imaging (T2WI), Fluid Attenuated Inversion Recovery (FLAIR), T2*-gradient recalled echo (T2*-GRE) and Susceptibility Weighted Imaging (SWI) in Traumatic Brain Injury (TBI).
Location and level of Etk expression in neurons are associated with varied severity of traumatic brain injury
10/1/2012 ... The observed correlation between Etk level and the number of impacts, the severity of impact, and the time course after impact, as well as its inverse correlation with distance away from injury site, support the potential of Etk as a possible indicator of trauma severity.
10/8/2012 ... The results suggest that subacute exercise, particularly if linked to a strong stress response, may be counterproductive. Here we show that cardiac and temperature autonomic function
are compromised during the subacute period following a mild TBI.
10/9/2012 ... These findings suggest that compromise to specific white matter pathways, including both axonal and myelination aspects, after a mild TBI underlie the susceptibility of these patients developing depression.
10/12/2012 ... The burden of disability caused by TBIs among children is primarily accounted for by mild injuries.
10/26/2012 ... Neurophysiological measures are excellent tools to assess the status and prognosis of patients with MTBI.
Factors associated with the withdrawal of life-sustaining therapies in patients with severe traumatic brain injury
11/14/2012 ... Death following decisions to withdraw life-sustaining therapies is associated with specific patient and clinical factors, and the intensity of care.
11/26/2012 ... Results suggest the potential of scalp EEG as an efficacious method for noninvasive diagnosis of TBI.
Supporting family members of people with traumatic brain injury using telehealth: A systematic review
1/3/2013 ... Telehealth programs for family members of people with traumatic
brain injury are feasible, with positive outcomes reported.
Evaluating the cognitive consequences of mild traumatic brain injury and concussion by using electrophysiology
1/28/2013 ... Abnormal ERP results are observed in patients after MTBI or sports concussion, even for those in the nonacute stage after their injury.
Mild traumatic brain injury diagnosis frequently remains unrecorded in subjects with craniofacial fractures
2/6/2013 ... TBIs remain frequently unrecorded in subjects with craniofacial
fractures. Recording of mild TBI slightly but insignificantly improved after the
implementation of new guidelines.
2/11/2013 ... It can be concluded that CSF NOx levels may serve as a potentially useful biomarker in severe TBI given its
significant association with ICP readings as well as Marshall CT grading.
A new method for evaluation of mild traumatic brain injury with neuropsychological impairment using statistical imaging analysis for Tc-ECD SPECT
2/13/2013 ... Using two analytic software packages, eZIS and vbSEE, we identified specific lesions with low regional Tc-99m ECD uptake possibly associated with NPIs after MTBI.
Meta-analysis of Glasgow Coma Scale and Simplified Motor Score in predicting traumatic brain injury outcomes
2/14/2013 ... In patients with TBI, SMS predicts different outcomes with similar
accuracy as GCS except mortality.
4/12/2013 ... The results suggest altered brain reactivity and connectivity in mTBI.
6/11/2013 ... This finding suggests that the "hypoxic challenge" paradigm developed here has potential clinical utility for assessing the effects of mTBI in individuals who appear asymptomatic under normal conditions.
6/21/2013 ... A rapid automated resting-state MEG imaging technique demonstrates abnormally decreased functional connectivity that may persist for years after TBI, including cases classified as "mild" by GCS criteria. Disrupted MEG connectivity can be detected even in some patients with normal findings on 3-T MRI. Analysis of follow-up MEG scans in a subgroup of patients shows that, over time, the abnormally reduced connectivity can improve, suggesting neuroplasticity during the recovery from TBI.
7/3/2013 ... The results suggest that driving ability after brain damage and cerebral disease with no severe neurological deficits can be measured with a few distinctive neuropsychological tests together with medical examination and on-road assessment.
7/24/2013 ... This study shows that pupillary responsiveness at admission, as well as 24-hour serum S100B levels, could serve as screening tools for the early detection of patients at risk for BD after severe TBI.
9/10/2013 ... This study suggests a unique injury- and temporally-specific interaction between TBI and genetic risk for depression.
Wide variation and systematic bias in expert clinicians' perceptions of prognosis following brain injury
9/11/2013 ... Clinical experts' predictions of outcome in TBI are widely variable and systematically pessimistic compared to IMPACT.
11/6/2013 ... In our screening of 509 patients, 28.5% showed lowered values in at least one hormone of the hypothalamus- pituitary axis, 4.5% in two or more axes.
Assessment of dietary adequacy for important brain micronutrients in patients presenting to a traumatic brain injury clinic for evaluation
12/17/2013 ... Diets failing to meet RDAs for important brain nutrients were common in an outpatient TBI clinic, with the worst mean neurobehavioral scores for those patients not meeting the estimated average requirements.
1/24/2014 ... Self-selected walking speeds higher than 1.0 m/s greatly increase the likelihood of running following brain injury.
Mobility after traumatic brain injury: relationships with ankle joint power generation and motor skill level
1/29/2014 ... Ankle joint power generation at push-off was the strongest predictor of mobility outcome after 6 months of rehabilitation in ambulant people with TBI.
1/30/2014 ... Findings indicate that no well-defined definition or clinical diagnostic criteria exist for mTBI and that diagnostic accuracy is currently insufficient for discriminating between mTBI and co-occurring mental health conditions for acute and historic mTBI.
Unexpected recovery of function after severe traumatic brain injury: the limits of early neuroimaging-based outcome prediction
5/2/2014 ... MRI data should be interpreted with caution when prognosticating for patients in traumatic coma.
Measurement of height velocity is an useful marker for monitoring pituitary function in patients who had traumatic brain injury
5/8/2014 ... A simple measurement of the height velocity at least 1 year after the TBI, is enough to recognize patients with a pituitary impairment related to GH deficiency.
5/26/2014 ... The case studies provide insight into the need for rehabilitation nurses to provide nutrition education to TBI survivors that will accommodate changes in lifestyle and activity after discharge.
6/4/2014 ... The unique characteristics of pediatric TBI warrant consideration when formulating a clinical trial design or predicting functional outcome using prognostic models developed from adult TBI data.
6/13/2014 ... The results suggest that neuropsychological measures of processing speed and cognitive flexibility may predict return to driving after TBI.
7/8/2014 ... The evidence suggests that repeat CT in patients with TBI results in a change in management for only a minority of patients.
Acute inflammatory biomarker profiles predict depression risk following moderate to severe traumatic brain injury
7/16/2014 ... Acute CSF IBR scores show promise for identifying individuals at risk for PTD.
7/24/2014 ... No endocrine sequelae have been detected in this population. The routine endocrine evaluation in children with mild to moderate TBI might not be justified.
8/25/2014 ... In more than half of the traumatic spinal cord injury patients referred for in-patient rehabilitation, acute care diagnoses of traumatic brain injury were missed.
12/23/2014 ... Vision-based testing is vital in the management of all forms of TBI and provides a sensitive approach for sideline or post-injury concussion screening.
3/5/2015 ... HP with TBI is common in patients who currently smoke and have lower TG levels (150 mg/dL). These patients would be monitored closely, and surgery may be considered before deterioration occurs.
Eye tracking detects disconjugate eye movements associated with structural traumatic brain injury and concussion
6/15/2015 ... Eye tracking may help quantify the severity of ocular motility disruption associated with concussion and structural brain injury.
9/25/2015 ... This study demonstrates the ability to separate PTSD and TBI from healthy controls, from each other, and detect their co-occurrence, even in highly comorbid samples, using SPECT.
11/25/2015 ... ICP monitoring is associated with improved survival in adult patients with sTBI.
Clinical signs of recovery in patients with unresponsive wakefulness syndrome after traumatic brain injury
9/2/2016 ... Visual fixation and visual pursuit are the commonest early clinical signs denoting MCS.
Driving assessment and rehabilitation using a driving simulator in individuals with traumatic brain injury
9/19/2016 ... Driving simulators represent a promising avenue for the assessment and rehabilitation of driving skills in TBI individuals as it allows control of stimuli in a safe, challenging and ecologically valid environment and offer the opportunity to measure and record driving performance.
2/29/2012 ... Moderate/severe TBI at an early age appears to be associated with lowered intellectual function and possibly behavior problems. A child's environment influences cognitive and behavior function after TBI.
3/8/2012 ... This study demonstrates that clinical factors at the time of injury, such as early post-traumatic seizures and intubation requirement, are associated with poorer developmental outcome.
Predictors of cognitive function and recovery 10 years after traumatic brain injury in young children
3/9/2012 ... Results confirm a high risk of persisting deficits after severe TBI in early childhood.
Reliable change in postconcussive symptoms and its functional consequences among children with mild traumatic brain injury
3/16/2012 ... Many children with mild TBI show reliable increases in postconcussive symptoms that are associated with significant functional impairment in their daily lives.
3/21/2012 ... Results suggest that the rate of TBIs within the juvenile offender population is significant and that there may be a relationship between TBIs and juvenile criminal behavior.
Parental distress, parenting practices, and child adaptive outcomes following traumatic brain injury
4/2/2012 ... Results suggest that parenting practices are an important area of focus for studies attempting to elucidate the relationship between parent and child functioning following TBI.
4/13/2012 ... ADHD following PTBI is even more common than the 30% rate the
current literature suggests.
4/18/2012 ... Good outcomes are contingent
on milder injuries, proxy reporting and early assessment whereas poor outcomes reflect more severe injuries and later assessment (≤6 months vs. ≥ 1 year post-trauma, respectively).
4/18/2012 ... Good outcomes are contingent on milder injuries, proxy reporting and early assessment whereas poor outcomes reflect more severe injuries and later assessment (≤6 months vs. ≥ 1 year post-trauma, respectively).
5/7/2012 ... Weight gain of children during the first year after TBI was rapid and excessive. Male sex was a risk factor for excessive weight gain.
Premorbid child and family functioning as predictors of post-concussive symptoms in children with mild traumatic brain injuries
5/11/2012 ... Counter to expectations, post-concussive symptoms following mild TBI may actually be more apparent among children from higher-functioning families with greater resources.
5/15/2012 ... Findings, which are similar to those reported after adult TBI, identify both similarities and differences in non-anxious and anxious depression following childhood TBI with respect to lesion laterality, genetic factors (in the form of family psychiatric history of anxiety disorder), age at injury, and more generalized affective dysregulation.
5/18/2012 ... These findings have important clinical and educational implications, suggesting that children with TBI, and particularly those with more serious injuries, are most vulnerable to attention deficits in the acute stages postinjury.
Association of persistent hyperglycemia with outcome of severe traumatic brain injury in pediatric population
5/24/2012 ... Early hyperglycemia is associated with poor outcome, and persistent hyperglycemia is a powerful and independent predictor of mortality in children and adolescents with severe TBI.
The invisible brain injury: The importance of identifying deficits following brain injury in children with intellectual disability
6/7/2012 ... This case study highlights the need for clinicians to consider the impact of TBI for children with ID, to avoid incorrectly attributing TBI symptoms to pre-existing problems.
Identification and validation of prognostic criteria for persistence of mild traumatic brain injury–Related impairment in the pediatric patient
6/8/2012 ... This is the first study demonstrating prognostic criteria that may greatly help physicians identify patients who would benefit from structured follow-up care after MTBI.
7/2/2012 ... Memory and executive function predict academic achievement after TBI in preschool children, although some of the associations may be accounted for by general intellectual functioning.
7/12/2012 ... Results indicated that,
at 10 years post child TBI, survivors' functional abilities fell overall within the low average to average range regardless of injury severity, suggesting no extreme impairments at a group level for any of the domains under investigation.
7/13/2012 ... The review illustrates that inhibitory control processes differ in terms of measurement, assessment, and neurological underpinnings, and also that childhood TBI may selectively disrupt particular forms of inhibition.
Healthcare utilization in the first year after pediatric traumatic brain injury in an insured population
7/20/2012 ... Children with a full benefits insurance plan do not access primary care routinely after TBI. These findings present a challenge for designing a system to screen children after TBI.
Self-reported health and influence on life situation 5-8 years after paediatric traumatic brain injury
8/14/2012 ... Young individuals experience sustained negative effects of childhood TBI on health and life situation.
9/5/2012 ... Point-in-time monitoring in a dynamic condition like TBI may underestimate the overall frequency of adverse events, like reduced PbtO(2), particularly when compared with continuous monitoring, which also has limitations, but provides a dynamic assessment over a longer time period.
9/7/2012 ... Findings suggest that longer-term treatment for behavior problems may be needed after severe TBI, particularly for those injured at an earlier age.
10/3/2012 ... Incidental findings in minor head trauma are common. Clinicians should be prepared to address these findings if
10/11/2012 ... Caregivers should be encouraged to provide positive environments and parenting styles, which may help reduce chronic behavioral problems after brain injury.
10/17/2012 ... Boys sustained injuries associated with a greater energy transfer, were less likely to use protective devices and more likely to be injured deliberately.
10/23/2012 ... TBI is associated with poorer intentional processing in school-age children and adolescents relative to peers with orthopedic injuries.
10/29/2012 ... Because transient and permanent hypopituitarism is common after TBI, survivors should be screened serially for possible endocrine disturbances.
11/12/2012 ... We found a significantly increased risk of TBI in socioeconomically deprived children, particularly among children with mental disorders, epilepsy, or both.
11/19/2012 ... Research in the area over
the last decade is encouraging but is limited by small sample sizes, variable practices in sample collection, inconsistent biomarker-related data elements and disparate outcome measures.
Mild traumatic brain injury: A description of how children and youths between 16 and 18 years of age perform leisure activities after 1 year
12/7/2012 ... Results showed that children and youths did not return to perform leisure activities.
12/10/2012 ... This study suggests that developmental change after TBI in childhood takes place on a continuum, with both chance of long-term catching up, and risk of poor development.
12/11/2012 ... Seizures are a common complication of severe TBI among children aged 0-3 years.
Association of persistent hyperglycemia with outcome of severe traumatic brain injury in pediatric population
12/17/2012 ... Early hyperglycemia is associated with poor outcome, and persistent hyperglycemia is a powerful and independent predictor of mortality in children and adolescents with severe TBI.
12/19/2012 ... Children with TBI have difficulties in mathematics, but do not have deficits in math fact retrieval, a signature deficit of math disabilities.
Predictors of 1-month and 1-year neurocognitive functioning from the UCLA longitudinal mild, uncomplicated, pediatric traumatic brain injury study
12/21/2012 ... Injury severity indicators or type of injury (head vs.
other body part) did not predict either 1-month or 12-month cognitive impairment status. Rather, premorbid variables that antedated the injury (parental education, premorbid behavior and/or learning problems, and school achievement)
predicted cognitive impairments.
1/18/2013 ... Adolescents who have headache on ED presentation and require hospital admission at the ED encounter
are at elevated risk for PCS after mild traumatic brain injury.
Association of traumatic brain injury with criminality in adolescent psychiatric inpatients from Northern Finland
2/5/2013 ... Our results suggest that clinicians working with mentally ill
adolescents who have experienced head injuries should be aware of the increased
risk for delinquency and violent tendencies occurring later in the adolescents' lives.
Neuropsychological recovery and quality-of-life in children and adolescents with growth hormone deficiency following TBI
2/18/2013 ... GHD following TBI is common in children and adolescents. Deficits in neurocognition and QoL impact recovery after TBI.
Variations in the quality of inpatient rehabilitation care to facilitate school re-entry and cognitive and communication function for children with TBI
2/20/2013 ... Substantial variations exist in the delivery of paediatric inpatient
rehabilitation care processes for managing school re-entry and cognitive and
communication impairments after traumatic brain injury.
Predictors of child post-concussion symptoms at 6 and 18 months following mild traumatic brain injury
2/21/2013 ... Children at risk of persistent PCS can be identified by higher levels of pre- and post-injury PCS, parent distress and poorer post-injury cognition.
Association of daytime somnolence with executive functioning in the first six months after adolescent traumatic brain injury
2/25/2013 ... The parent report of daytime somnolence correlated with TBI severity and predicted executive functioning difficulties of the teens in everyday circumstances.
Injury versus noninjury factors as predictors of postconcussive symptoms following mild traumatic brain injury in children
3/5/2013 ... Injury characteristics predict PCS in the first months following
mild TBI but show a decreasing contribution over time. In contrast, noninjury factors are more consistently related to persistent PCS.
3/8/2013 ... Severe TBI in children is associated with detrimental peer relationships that are related to focal volumetric reductions in white matter within regions of the brain involved in social information-processing.
3/14/2013 ... Deficits in understanding the social, conative function of indirect
speech acts like irony and empathy have widespread and deep implications for
social function in children with TBI.
Effects of moderate to severe traumatic brain injury on anticipating consequences of actions in adolescents
3/21/2013 ... For long-term consequences, the relations to the posterior cingulate, superior medial frontal, and precentral regions, and to a lesser extent, the middle temporal region, were stronger for the TBI group (p < .01).
Emotional expression and socially modulated emotive communication in children with traumatic brain injury
3/25/2013 ... Children with TBI have difficulty understanding the dual role of
facial emotions in expressing feelings and communicating socially relevant but
deceptive emotions, and these difficulties likely contribute to their social problems.
Cognitive recovery and development after traumatic brain injury in childhood: a person-oriented, longitudinal study
3/27/2013 ... An acute profile of higher FFD and lower PS seemed to reflect injury
consequences and were followed by developmental gains. These results challenge previous findings, and warrant further investigation.
Predicting postconcussion syndrome after mild traumatic brain injury in children and adolescents who present to the emergency department
4/19/2013 ... Adolescents who have
headache on ED presentation and require hospital admission at the ED encounter
are at elevated risk for PCS after mild traumatic brain injury.
Predictors of 1-month and 1-year neurocognitive functioning from the UCLA longitudinal mild, uncomplicated, pediatric traumatic brain injury study
4/23/2013 ... Injury severity indicators or type of injury did not predict either 1-month or 12-month cognitive impairment
status. Rather, premorbid variables that antedated the injury (parental education, premorbid behavior and/or learning problems, and school achievement) predicted cognitive impairments.
Social interaction in young children with inflicted and accidental traumatic brain injury: Relations with family resources and social outcomes
5/9/2013 ... Low social responsiveness after TBI may be an early marker for later cognitive and adaptive behavior difficulties.
5/31/2013 ... The finding indicates that TBI results in deficient inhibition regardless of the development of S-ADHD.
Hypernatremia is associated with increased risk of mortality in pediatric severe traumatic brain injury
6/6/2013 ... Acquired hypernatremia appears to signal higher risk of mortality in pediatric sTBI and is associated with a higher discharge level of care in sTBI survivors.
Working memory and corpus callosum microstructural integrity following pediatric traumatic brain injury
6/13/2013 ... In both groups of children, lower FA and/or higher radial diffusivity in callosal subregions connecting anterior and posterior parietal cortical regions predicted
poorer verbal working memory; higher radial diffusivity in callosal subregions
connecting anterior and posterior parietal, as well as temporal, cortical regions predicted poorer visuospatial working memory.
6/20/2013 ... Moderate-severe pediatric TBI was associated with sleep inefficiency in the form of sleep onset and maintenance problems.
7/11/2013 ... Social participation appeared most vulnerable, with more severe injuries leading to greater problems.
8/5/2013 ... One-third (32%) of young people reported ever experiencing a TBI, and 13% reported multiple TBIs.
8/15/2013 ... Low social responsiveness after TBI may be an early marker for later cognitive and adaptive behavior difficulties.
Prospective evaluation of the nature, course, and impact of acute sleep abnormality after traumatic brain injury
8/19/2013 ... Results suggest that sleep abnormalities after TBI are prevalent and decrease over time. However, a high percent remained with SWCD throughout the course of rehabilitation intervention.
Individual profiles of predictors and their relations to 10 years outcome after childhood traumatic brain injury
8/26/2013 ... The findings suggest that pre-injury adaptive function is an influential predictor of outcome following moderate CTBI.
8/28/2013 ... The results demonstrated that measurement of executive function behaviors is an important research and clinical tool for prediction of functional outcomes in pediatric TBI.
9/4/2013 ... Findings indicate that web-based CAPS improves primary caregiver-rated executive functioning within the first 12 months after TBI in older adolescents.
9/26/2013 ... Mild head injuries, especially incurred repeatedly, may still be a significant risk for adverse behaviours in children.
10/8/2014 ... Language appears vulnerable to TBI and should be investigated as a matter of course in clinical assessments of TBI recovery.
10/9/2013 ... The current state of acute rehabilitation care for children with traumatic brain injury is variable across different quality-of-care indicators addressing neurobehavioral and psychosocial needs and facilitating community reintegration of the patient and the family.
11/8/2013 ... These findings, though preliminary, indicate possible alterations in mother-child interactions in the months following a TBI.
12/9/2013 ... Significant gender differences exist from infancy.
Juvenile traumatic brain injury evolves into a chronic brain disorder: Behavioral histological changes over 6months
12/16/2013 ... These findings suggest that this model of juvenile TBI produces long-term impairments comparable to those reported clinically.
1/2/2014 ... Children with history of iTBI show high risk for endocrine dysfunction, including elevated prolactin and growth abnormalities.
Adolescents' internalizing problems following traumatic brain injury are related to parents' psychiatric symptoms
1/22/2014 ... Parent and teen emotional problems are associated following adolescent TBI.
Examining acute rehabilitation outcomes for children with total functional dependence after traumatic brain injury
1/28/2014 ... Even children with the most severe brain injuries, who enter rehabilitation completely dependent for all daily activities, have the potential to make significant gains in functioning by discharge and in the following few months.
The role of serious concomitant injuries in the treatment and outcome of pediatric severe traumatic brain injury
1/31/2014 ... Head injury is the most important prognostic factor in mortality for sTBI pediatric patients, but the presence of serious concomitant injuries does contribute to greater morbidity, including longer stays, more infections, fewer ventilator-free days, and a higher level of care required on discharge from hospital.
2/3/2014 ... Findings lend support to the vulnerability of the immature 'social brain' network to early disruption, and underscore the need for context-sensitive rehabilitation that optimizes early family environments to enhance recovery of emotion perception skills after childhood TBI.
Social communication mediates the relationship between emotion perception and externalizing behaviors in young adult survivors of traumatic brain injury
2/5/2014 ... Findings indicate that socio-cognitive impairments may indirectly increase the risk for externalizing behaviors among young adult survivors of childhood TBI.
2/12/2014 ... Our findings show a higher likelihood of manifesting mood disorders in adolescents and young adults who sustained a prior TBI.
2/18/2014 ... Parenting interventions may provide essential support for parents in adjusting to and managing their child's difficulties and the efficacy of existing programmes needs evaluation.
Hidden loss: A qualitative explorative study of children living with a parent with acquired brain injury
2/19/2014 ... The findings indicated that the children seemed to make a special effort to hide their feelings of loss and grief in order to protect the ill parent.
Parent perceptions of early prognostic encounters following children's severe traumatic brain injury
3/3/2014 ... Parents blatantly and tacitly revealed their beliefs that providers play an important role in shaping parent reception of and synthesis of prognostic information, which constructs the family's ability to cope and participate in shared decision-making.
3/13/2014 ... Early pain experience at 3 months following TBI was associated with a significantly poorer long-term health-related quality of life.
Predicting adult offending behavior for individuals who experienced a traumatic brain injury during childhood
4/3/2014 ... Individuals who experienced childhood TBI are at increased risk of offending behavior.
4/4/2014 ... Traumatic brain injury is associated with increased criminal behavior and may represent a risk factor for offending.
4/29/2014 ... Findings lend support to the vulnerability of the immature "social brain" network to early disruption and underscore the need for context-sensitive rehabilitation that optimizes early family environments to enhance recovery of EP skills after childhood TBI.
Social communication mediates the relationship between emotion perception and externalizing behaviors in young adult survivors of pediatric traumatic brain injury
4/30/2014 ... Findings indicate that socio-cognitive impairments may indirectly increase the risk for externalizing behaviors among young adult survivors of childhood TBI, and underscore the need for targeted social skills interventions delivered soon after injury, and into the very long-term.
5/21/2014 ... The authors conclude that psychological and behavioral difficulties are very common among school-aged children with acquired brain lesions, and their relevance and impact must necessarily be considered.
5/30/2014 ... This extends the generalisability of earlier suggestions of a relationship between TBI and offending, and various factors thought likely to mediate the relationship.
6/20/2014 ... Students with TBI can adapt and flourish in a school based setting provided that therapies and learned strategies are targeted to their specific needs.
6/25/2014 ... Findings show a higher likelihood of manifesting mood disorders in adolescents and young adults who sustained a prior TBI.
Parent psychological functioning and communication predict externalizing behavior problems after pediatric traumatic brain injury
6/27/2014 ... Overall, higher ratings of effective parent communication were associated with fewer externalizing behavior problems, whereas poorer caregiver psychological functioning was associated with greater adolescent externalizing behaviors.
Family function and its relationship to injury severity and psychiatric outcome in children with acquired brain injury
7/2/2014 ... Screening for some aspects of family functioning before injury and family function during the rehabilitation phase may identify children at risk of psychiatric disorders.
7/17/2014 ... Severe dysphagia among postsurgical pediatric patients after TBI is relatively common, and those with severe dysphagia have a greater need for medical services.
8/11/2014 ... At one year post-severe TBI, pituitary dysfunction was found in 8% of our study sample.
8/21/2014 ... The prognosis of MTBI is favorable in children. Most appear to recover functionally from a physical and psychological perspective.
8/28/2014 ... Findings indicated a deterioration of social participation skills post-injury, particularly for those sustaining a more severe injury, and a consistently higher rate of impairment in social and behavioral outcomes in the TBI group.
9/18/2014 ... These findings provide preliminary evidence for the use of this web-based positive parenting skills intervention to improve parenting skills and child behavior following abusive head trauma.
10/3/2014 ... Parental TBI is associated with increased use of specialized psychiatric services by children.
10/6/2014 ... Elevated prevalence and incidence of TBI among incarcerated adolescents may relate to criminal justice involvement as well as friction in jail.
Sleep problems and their relationship to cognitive and behavioral outcomes in children with traumatic brain injury
11/7/2014 ... Sleep problems significantly increase the risk of poor psychosocial outcomes.
The results document unmet long-term behavioral health needs after both TBI and OI in children and underscore the importance of monitoring and treatment of postinjury behavior problems.
11/19/2014 ... Children with traumatic brain injury suffer from cognitive disorders and behavioural problems, especially impulsivity, physical and verbal aggression, increased anxiety, and disorganization.
12/2/2014 ... There are studies that demonstrate benefits of varying pharmacologic and cognitive therapies for the management of attention problems after TBI.
2/3/2015 ... There is no evidence that therapeutic hypothermia improves prognosis of children with TBI.
2/12/2015 ... There are strong and demographically stable associations between TBI and substance use.
Meta-analysis of the efficacy and safety of therapeutic hypothermia in children with traumatic brain injury
2/16/2015 ... Children suffered TBI may not be able to benefit from therapeutic hypothermia, it may increase risk of fatality and arrhythmia.
2/19/2015 ... School-aged children with mTBI are at risk for persistent symptoms of behavior problems.
The trajectory of long-term psychosocial development 16 years following childhood traumatic brain injury
2/26/2015 ... This study confirmed previous literature that CTBI is associated with increased levels of psychosocial problems.
Autologous bone marrow mononuclear cells reduce therapeutic intensity for severe traumatic brain injury in children
3/4/2015 ... IV autologous bone marrow-derived mononuclear cell therapy is associated with lower treatment intensity required to manage intracranial pressure, associated severity of organ injury, and duration of neurointensive care following severe traumatic brain injury.
3/19/2015 ... Findings indicated a deterioration of social participation skills post-injury, particularly for those sustaining a more severe injury, and a consistently higher rate of impairment in social and behavioral outcomes in the TBI group.
4/24/2015 ... There is a high prevalence of TBI in juvenile offenders in custody, with many experiencing multiple episodes.
Gross Motor Function Measure-66 trajectories in children recovering after severe acquired brain injury
5/1/2015 ... Children sustaining hypoxic-ischaemic injuries made the slowest and least complete recoveries. Older children made faster gross motor recoveries after controlling for aetiology.
5/8/2015 ... These findings extend earlier reports that the psychiatric morbidity after mTBI in children is more common than previously thought, and moreover, it is linked to preinjury individual variables and injury
characteristics and is associated with postinjury adaptive and neurocognitive functioning.
6/29/2015 ... Two years after onset, the parent-reported that impact of ABI on the family as measured by the PedsQL FIM was considerable especially in patients with moderate/severe NTBI.
Psychological problems, self-esteem and body dissatisfaction in a sample of adolescents with brain lesions
7/10/2015 ... Adolescents with acquired brain lesions were at higher risk to develop psychological and behavioural difficulties.
Long-term behavioral outcomes after counselor-assisted problem solving for adolescents with traumatic brain injury
7/16/2015 ... Findings suggest that CAPS may lead to long-term improvements in behavior problems among older adolescents and those with pretreatment symptoms.
7/17/2015 ... Our findings suggest that adolescents may experience subjective and objective sleep disturbances up to one year following mTBI.
7/22/2015 ... The empirical studies reviewed demonstrate the increased risk for negative behavioral and cognitive outcomes following early childhood TBI.
7/23/2015 ... Using a survival analysis with time-dependent indicators of TBI, we found a higher risk of suicide for people who sustained a TBI during childhood.
9/1/2015 ... Survivors of TBI should undergo endocrine surveillance by 6-12 months after injury, and then yearly, to ensure early detection of deficiencies in hormonal production that can substantially influence growth, puberty and quality of life.
9/15/2015 ... There is a considerable risk of developing pituitary dysfunction after TBI in children and adolescents.
10/7/2015 ... The risk of sustaining a TBI is increased by pre-existing psychopathology and psychosocial adversity.
Availability of outpatient rehabilitation services for children after traumatic brain injury: Differences by language and insurance status
10/30/2015 ... Children in households with limited English proficiency and Medicaid faced significant barriers in availability and proximity of outpatient rehabilitation services.
11/4/2015 ... Lapses of attention represent a core attention deficit in children with mild TBI .
11/19/2015 ... Problem-focused coping strategies are associated with higher levels
of effective communication and lower levels of caregiver negativity during the initial months after adolescent TBI.
12/02/2015 ... While there was evidence of recovery of OD over time in pediatric TBI, the majority of children with severe OD did not show any recovery.
12/7/2015 ... The findings suggest that, while children with TBI display atypical
SPS skills, SPS cannot be used in isolation to accurately predict social adjustment.
12/8/2015 ... TBI remains a disabling and common condition among adolescents and the consumption of alcohol, energy drinks, and alcohol mixed with energy drinks further increase the odds of TBI among adolescents.
12/17/2015 ... Results demonstrate that low PbtO2 may be prognostic of not only mortality but also neuropsychological outcomes.
Web-based parenting skills program for pediatric traumatic brain injury reduces psychological distress among lower-income parents
12/22/2015 ... Parent training interventions post-TBI may be particularly valuable
for lower-income parents who are vulnerable to both environmental and injury-related stresses.
12/28/2015 ... The findings show that young patients experience psychological dysfunction.
Arithmetic difficulties in children with mild traumatic brain injury at the subacute stage of recovery
3/9/2016 ... Immediately after the injury, arithmetic difficulties in children with mTBI are particularly pronounced on more complex arithmetical problems that are less automated.
3/16/2016 ... Poorer long-term social outcomes were associated with family dysfunction and poorer parent health at 24-months post injury.
3/30/2016 ... Findings suggest that the emergence of novel anxiety disorder after TBI might be related to a broader problem of affective dysregulation especially in younger children and those with a vulnerability even to pre-injury anxiety.
4/12/2016 ... Higher symptom burden was reported by the athletes and parents in the additional-impact group.
4/21/2016 ... Children with severe TBI had consistently high usage of school services
and low school competency ratings than children with orthopedic injuries and healthy controls.
6/23/2016 ... The findings suggest that premorbid factors influence cognitive outcomes nearly as much as the occurrence of a msTBI.
Impact of traumatic brain injury on social cognition in adolescents and contribution of other higher order cognitive functions
6/30/2016 ... Findings suggest the presence of primary deficits in social cognition following TBI in adolescence.
Moderate/severe pediatric TBI has a negative impact on generalization of learning, which may contribute to post-injury externalizing problems.
7/22/2016 ... Somatization is associated with delayed symptom resolution in this cohort of children with concussion.
Adaptive Functioning Following pediatric traumatic brain injury: Relationship to executive function and processing speed
8/30/2016 ...Children with STBI experience deficits in adaptive functioning, particularly in social adjustment, with less pronounced deficits in conceptual and practical skills.
9/12/2106 ... TBI in childhood is associated with a greater likelihood of developing ADHD.
Pediatric TBI has a negative impact on generalization of learning, which may contribute to post-injury externalizing problems.
Sleep difficulties are common following mild TBI in children and are predictive of longer-term outcomes. Identifying children with sleep difficulties
Serum biomarkers help predict attention problems in critically ill children with traumatic brain injury
10/20/2016 ...Combining baseline assessment of attention with measurement of serum biomarkers shows promise as reliable, early predictors of long-term attention after childhood traumatic brain injury.
Executive function after severe childhood traumatic brain injury - Age-at-injury vulnerability periods
11/3/2016 ... The relationship between age at injury and outcome is not linear. Relying on only performance-based EF tests can underestimate EF impairment.
Executive function after severe childhood traumatic brain injury - Age-at-injury vulnerability periods
11/3/2016 ... The relationship between age at injury and outcome is not linear. Relying on only performance-based EF tests can underestimate EF impairment.
11/4/2016 ... Older children and children from a single-parent household were found to have higher fatigue levels.
11/22/2016 ... JHTS occurs more often in children up to 10 years with falls as major cause of injury.
Academic outcome, participation and health-related quality of life following childhood severe traumatic brain injury
12/1/2016 ... Severe childhood TBI leads to severe and long-standing impairments, evident several years post-injury, with consequences on school integration, independence, participation and HRQOL.
12/2/2016 ... Severe childhood TBI leads to severe and long-standing cognitive impairments, without significant improvement over time.
12/8/2016 ... Results underscore the need to assess fatigue and associated sleep-wake disturbance and depression after child TBI from both parent and child perspectives.
12/12/2016 ... These data suggest that subtle motor deficits are present after milder forms of TBI and, particularly those related to balance and gait, may persist even 12 months postinjury.
12/19/2016 ... Injury characteristics were significantly associated with PCS for 3
months following mTBI but the association weakened over time.
Neurocognitive predictors of posttraumatic stress disorder symptoms in children 6 months after traumatic brain injury
12/20/2016 ... PTSD involves a complex interplay between attention and memory functions post pediatric TBI.
1/17/2017 ... Fatigue was predicted by postinjury depression and sleep disturbance for parent, but not child ratings.
Short-term efficacy and tolerability of methylphenidate in children with traumatic brain injury and attention problems
1/18/2017 ... IR-MPH was found as a safe and
effective treatment option for ADHD symptoms after TBI.
Factor associated with an increased risk for subsequent development of Alzheimer's disease after TBI
5/3/2012 ... Induction of MCP-1 in response to TBI might be a potential predisposing factor that may increase the risk for development of Alzheimer's disease.
7/10/2012 ... This review focuses on AD related genes which are expressed during TBI and its relevance to progression of the disease.
12/12/2012 ... The findings of this study suggest an increased risk of dementia among individuals with TBI.
Symptomatic white matter changes in mild traumatic brain injury resemble pathologic features of early alzheimer dementia
8/30/2013 ... The distribution of white matter abnormalities in patients with symptomatic mild TBI is strikingly similar to the distribution of pathologic abnormalities in patients with early Alzheimer dementia.
9/27/2013 ... It is now becoming clear that a history of TBI predisposes the individual to AD later in life.
10/29/2013 ... We conclude that TBI with chronic deficit or dysfunction is associated with an increased odds ratio for dementia.
11/26/2013 ... The results of our meta-analysis indicate that a history of head trauma that results in concussion is associated with a higher risk of developing PD.
Symptomatic white matter changes in mild traumatic brain injury resemble pathologic features of early Alzheimer dementia
3/14/2014 ... The distribution of white matter abnormalities in patients with symptomatic mild TBI is strikingly similar to the distribution of pathologic abnormalities in patients with early Alzheimer dementia.
The association of traumatic brain injury with rate of progression of cognitive and functional impairment in Alzheimer's disease
9/23/2014 ... History of TBI and its recency may be a useful factor to predict functional progression in the course of AD.
1/30/2015 ... Findings from this exploratory study indicate that a past TBI may put older adults at a higher risk for exacerbated age-related cognitive decline compared to older adults with no history of TBI.
2/13/2015 ... Those with moderate to severe TBI at 55 years or older or mild TBI at 65 years or older had an increased risk of developing dementia.
3/6/2015 ... TBI may increase the FTD risk and influence clinical symptomatology and severity in FTD subtypes.
3/25/2015 ... Among patients age ≥55 presenting to inpatient/ED settings with trauma, TBI is associated with a 44% increased risk of developing PD.
12/15/2015 ... TBI history with LOC occurring more than 1 year prior to diagnosis is associated with an earlier age of symptom onset and diagnosis in patients with bvFTD.
4/11/2016 ... This study suggests that the use of hypnotics is associated with an increased risk of dementia in TBI patients with or without insomnia, whereas insomnia alone is not.
6/7/2016 ... Results suggest that head injury in early life increases the risk of PD.
6/24/2016 ... A history of TBI may accelerate the AAO of cognitive impairment by two or more years.
Association of traumatic brain injury with Late-life neurodegenerative conditions and neuropathologic findings
10/13/2016 ...Pooled clinical and neuropathologic data from 3 prospective cohort studies indicate that TBI with LOC is associated with risk for Lewy body accumulation, progression of parkinsonism, and PD, but not dementia, AD, neuritic plaques, or neurofibrillary tangles.
10/26/2016 ...These results were consistent with
reports of TBI as a significant risk factor for cognitive decline in older adults, and TBI is associated with an earlier AAO found in patients with MCI or AD.
Association of traumatic brain injury with late-life neurodegenerative conditions and neuropathologic findings
1/4/2017 ... Pooled clinical and neuropathologic data from 3
prospective cohort studies indicate that TBI with LOC is associated with risk for
Lewy body accumulation, progression of parkinsonism, and PD, but not dementia,
AD, neuritic plaques, or neurofibrillary tangles.
1/6/2017 ... Findings suggest that a history of mild-moderate TBI is a risk factor
for cognitive decline in individuals with PD.
Mild Traumatic Brain Injury
7/15/2013 ... Pain in patients with mTBI was associated with more rapid qEEG activity, mostly during REM sleep, suggesting that pain is associated with poor sleep and is a critical factor in managing post-concussion symptoms.
7/19/2013 ... Results suggest that preinjury depressed mood and resilience are significant contributors to the severity of postinjury anxiety and postconcussion symptoms, even after accounting for effects of other specific host factors.
8/2/2013 ... TBI is an independent significant risk factor of developing dementia even in the mild type.
Postconcussive complaints, anxiety, and depression related to vocational outcome in minor to severe traumatic brain injury
8/21/2013 ... Anxiety and depression are related to vocational outcome after TBI, with a different profile in the minor TBI category, partly due to sex differences.
Posttraumatic migraine as a predictor of recovery and cognitive impairment after sport-related concussion
10/21/2013 ... Results suggest that PTM is associated with cognitive impairments and protracted recovery and that headache alone is not a good predictor of recovery.
Repetitive traumatic brain injury, psychological symptoms, and suicide risk in a clinical sample of deployed military personnel
10/22/2013 ... Suicide risk is higher among military personnel with more lifetime TBIs, even after controlling for clinical symptom severity.
History of mild traumatic brain injury is associated with deficits in relational memory, reduced hippocampal volume, and less neural activity later in life
11/4/2013 ... The present findings extended previous results by demonstrating that these individuals also had smaller bilateral hippocampi, and had reduced neural activity during memory performance in cortical regions important for memory retrieval.
11/7/2013 ... There were no significant differences between the uncomplicated MTBI and healthy control group on any measures of learning and memory.
11/15/2013 ... Headache after mTBI is very common and persistent across the first year after injury.
11/20/2013 ... Patients who sustain mild TBIs in the setting of a premorbid diagnosis of ADHD are more likely to be moderately disabled by the injury than are patients without ADHD.
Reduced contribution of executive functions in impaired working memory performance in mild traumatic brain injury patients
12/5/2013 ... We suggest that MTBI may lead to WM deficits as the contribution of executive processes to support the WM is diminished following MTBI.
1/13/2014 ... Long-term consequences were present for approximately 50% of the patients 3 years after mild traumatic brain injury and were also reported 11 years after mild traumatic brain injury.
Sex-differences in symptoms, disability, and life satisfaction three years after mild traumatic brain injury
1/14/2014 ... There are sex differences in outcome 3 years after mild traumatic brain injury. Women and men should be analysed separately.
1/15/2014 ... In this study, children with mild traumatic brain injury did not differ from the norm in terms of fine- or gross-motor proficiency compared with a control group of uninjured children, but a difference in balance skill (p = 0.03), mixed-handedness (p = 0.02) and tremor (p = 0.004) was detected, to the injured children's detriment.
3/4/2014 ... Although deterioration rarely occurs in patients with mild brain injury, those with coagulopathy, anticoagulant drug use, GCS of 13-14, increased age, midline shift, cerebral contusions, diffuse cerebral oedema andSDH were more prone to deterioration.
Combining biochemical and imaging markers to improve diagnosis and characterization of mild traumatic brain injury
4/7/2014 ... Blood biomarkers and advanced MRI may correlate or complement each other in different aspects of mTBI detection and characterization.
Perception of recovery after pediatric mild traumatic brain injury is influenced by the "Good Old Days" bias
4/18/2014 ... The "good old days" bias is present in pediatric mTBI by 1-month post-injury, influences retrospective symptom reporting, and has measureable implications for determining recovery in research and clinical practice.
5/13/2014 ... Mild traumatic brain injury is an independent significant risk factor for death in the elderly.
5/14/2014 ... Metabolic measurements in the thalamus and CSV can potentially serve as diagnostic and prognostic markers of mTBI.
Recovery from sleep disturbance precedes that of depression and anxiety following mild traumatic brain injury
5/15/2014 ... Daytime sleepiness is not affected by mTBI. However, mTBI causes depression and anxiety and diminished sleep quality. Although all these conditions improve significantly within 6 weeks post-mTBI.
Elevated C-reactive protein levels may be a predictor of persistent unfavourable symptoms in patients with mild traumatic brain injury
5/16/2014 ... Among patients with mTBI, baseline elevated CRP levels may be an independent predictor of persistent persistent PCS, psychological problems and cognitive impairment.
6/12/2014 ... The under-arousal in traumatic brain injury has been hypothesized to be associated with ventromedial prefrontal cortex disruption.
Prevalence of and risk factors for poor functioning after isolated mild traumatic brain injury in children
6/18/2014 ... Children and adolescents sustaining a mild TBI who are socioeconomically disadvantaged may require additional intervention to mitigate the effects of mild TBI on their functioning.
7/3/2014 ... MTBI patients with multifocal white matter changes did not show evidence of worse symptoms, cognitive impairment, or slower return to work compared to MTBI patients with broadly normal white matter.
8/15/2014 ... Up to 1 year after sustaining an MTBI during a motor vehicle collision, multiple symptoms and pain in several anatomical sites are common.
8/18/2014 ... MTBI affects almost a quarter of persons reporting an injury after a traffic collision. The median time to recovery is 100 days, but 23% have still not recovered by 1 year.
8/19/2014 ... There is a lack of evidence of an increased risk of dementia after MTBI. In children, objective evidence of CCI exists only for complicated MTBI.
8/20/2014 ... The best available evidence argues against an important causal association between MTBI and PD.
9/4/2014 ... Moderate to severe depressive symptoms in the month before injury seems to be a possible risk factor for poor affective/behavioral, cognitive, and mental health-related quality-of-life outcomes after MTBI.
The influence of injury cause, contact-sport participation, and personal knowledge on expectation of outcome from mild traumatic brain injury
9/16/2014 ... Personal knowledge of mTBI, but not contact sport participation, may account for some variability in mTBI beliefs and expectations.
9/26/2014 ... After a concussion, physical symptoms such as headache predominate immediately after the injury, emotional symptoms tend to develop later in the recovery period, and cognitive symptoms may be present throughout.
10/10/2014 ... Neural adaptation to PS appears to be a long-term process.
Reduced GABAergic inhibition in the basolateral amygdala and the development of anxiety-like behaviors after mild traumatic brain injury
10/24/2014 ... These results suggest
that mTBI causes not only a significant reduction in inhibition in the BLA, but
also an increase in neuronal excitability, which may contribute to hyperexcitability and the development of anxiety disorders.
10/27/2014 ... The literature documents a significant association between mTBI and ADHD.
11/20/2014 ... Study found a 25% prevalence of GHD with mild TBI as shown by glucagon stimulation.
11/21/2014 ... Activities of daily living, balance in postural stability and sensory integration were strongly impaired in patients with MTBI.
12/18/2014 ... There is a difference magnitude and nature of perceived sleep disturbance following mTBI compared with controls, where people with mTBI report poorer sleep quality and greater impairment from their sleep.
Injury timing alters metabolic, inflammatory and functional outcomes following repeated mild traumatic brain injury
12/30/2014 ... Too rapid return to activity after a traumatic brain injury can induce permanent damage and disability.
1/14/2015 ... Empirical evidence supports the inclusion of young age as a modifying factor in sports concussion.
In this large-scale, retrospective survey study, boys and girls with ADHD were significantly more likely to report a history of concussion.
1/20/2015 ... These findings provide new evidence of acute white matter alteration at both global and regional network level following mTBI in children.
1/29/2015 ... Findings support that mTBI may have a prolonged neurological impact.
3/9/2015 ... This study demonstrated traumatic axonal injury of the CST using configurational evaluation of DTT in patients with mild TBI.
3/10/2015 ... Activities of daily living, balance in postural stability and sensory integration were strongly impaired in patients with mTBI.
3/16/2015 ... The strongest predictors of lower 3- and 6-month GOS-E were older age, pre-existing psychiatric conditions, and lower education.
3/20/2015 ... Subjects with symptomatic mTBI had statistically larger position errors, smaller saccadic amplitudes, smaller predicted peak velocities, smaller peak accelerations, and longer durations.
Do children and adolescents With mild traumatic brain injury and persistent symptoms benefit from treatment?
3/31/2015 ... A variety of medical and nonmedical interventions have been used to treat the persistent symptoms of mTBI in children and adolescents.
4/6/2015 ... Females may have a higher risk of epilepsy and suicide, and use more healthcare services; males may be at higher risk for schizophrenia.
6/18/2015 ... Results suggest that alterations in cortical thickness may occur at an early stage of mTBI and that frontal cortex structure may change dynamically over the initial 3 months after mTBI.
6/23/2015 ... mTBI patients had significantly smaller volumes in several regions including the caudate, putamen, and thalamus when assessed two months after injury.
6/24/2015 ... Older age at injury, female gender, and acute symptom report were predictors of poor symptomatic outcome at three months. Socioeconomic status was the only significant predictor of poor cognitive outcome at three months.
7/27/2015 ... Sleep difficulties in young adults may persist for ≤3 months after MTBI and exceed those after orthopedic injury.
Evaluation of white matter injury patterns underlying neuropsychiatric symptoms after mild traumatic brain injury
8/11/2015 ... Unique white matter injury patterns were seen for two major posttraumatic neuropsychiatric symptoms.
8/13/2015 ... There is evidence for both white and grey matter damage in participants with mTBI over 1 year after injury.
This panel of biomarkers discerns, with high accuracy, patients with isolated concussion from uninjured individuals within the first 8 h after accident. These biomarkers can also aid in diagnosing concussion in the presence of OI.
9/8/2015 ... Headache is common in the year following mTBI, with younger people, persons who previously had headaches, and persons with PTSD more likely to report
Chronic or Worsening headache.
9/29/2015 ... Older age at injury, female sex, and acute symptom report were predictors of poor symptomatic outcome at 3 months. Socioeconomic status was the only significant predictor of poor cognitive outcome at 3 months.
Association of acute posttraumatic stress, depression, and pain to cognitive functioning in mild traumatic brain injury
10/1/2015 ... Acute posttraumatic stress and pain show strong associations with selective and sustained attention following mTBI.
Heart rate variability and serum level of insulin-like growth factor-1 are correlated with symptoms of emotional disorders in patients suffering a mild traumatic brain injury
10/9/2015 ... Both HRV and IGF-1 were correlated with symptom of depression while only HRV was correlated with symptom of anxiety in mTBI patients.
10/29/2015 ... At the population level, costs following mild TBI far exceeded those of more severe cases.
Preinjury emotional-behavioral functioning of children with lingering problems after mild traumatic brain injury
11/3/2015 ... Premorbid emotional-behavioral difficulties may play an important role
in the establishment or maintenance of lingering symptoms after pediatric mild TBI.
11/24/2015 ... Our study found a 25% prevalence of GHD in veterans with mild TBI as shown by glucagon stimulation.
11/30/2015 ... Higher symptom burden was reported by the athletes and parents in the additional-impact group at the time of first visit.
12/1/2015 ... These data support the hypothesis that physiological changes persist beyond the point of clinical recovery after SRC.
Neuropsychological outcome and its correlates in the first year after adult mild traumatic brain injury
12/4/2015 ... Significant improvements were noted across measures over time, a significant proportion of individuals still perform poorly on neuropsychological measures 12-months after mild TBI.
12/14/2015 ... Emotional symptoms were commonly reported among pediatric patients with SRC referred to a multidisciplinary pediatric concussion program.
12/31/2015 ... These findings suggested that mTBI patients experienced more serious subjective insomnia symptoms than objective measurement, which were associated with HPA dysfunction.
1/4/2015 ... Sport-related concussion can negatively influence physical and emotional function, academics, and interpersonal interactions as perceived by adolescent student-athletes and their parents.
1/6/2016 ... The mTBI group performed significantly worse on all of the executive and nonexecutive measurements with the exception of Category Fluency.
1/19/2016 ... Children with mTBI recovered in terms of mathematical abilities.
1/27/2016 ... Workers with delayed recovery from mTBI experience difficulty with community integration.
Effect of age on working memory performance and cerebral activation after mild traumatic brain injury
2/2/2016 ... The different manifestations of postconcussion symptoms at functional MR imaging between younger and older patients confirmed the important role of age in the activation, modulation, and allocation of WM processing resources after MTBI.
Role of the thalamus in natural recovery of cognitive impairment in patients with mild traumatic brain injury
2/17/2016 ... The correlation between improvement in cognitive-scores and changes in thalamic tensor and volume measures reflect the role of the thalamus in natural-recovery after mTBI.
mTBI may be linked to subtle executive memory deficits. Lower cognitive reserve appears to be a risk factor for PCS and indicates individual vulnerabilities.
2/23/2016 ... These results indicate the importance of properly identifying and treating symptoms of posttraumatic stress in veterans with a history of mTBI, as posttraumatic stress symptoms appear to be strongly related to SWL in those with a history of mild TBI.
2/29/2016 ... Following mild traumatic brain injury, children acutely demonstrate significantly more rigid sway patterns with eyes closed than with eyes open, which were highlighted by the Romberg quotient.
3/7/2016 ... These results support ADHD as an antecedent risk factor for mTBI in student athletes and that its presence complicates the course of mTBI.
Headache is common in the year after MTBI, with younger people, persons who previously had headaches, and persons with PTSD more likely to report chronic or worsening headache.
Trajectories and associated factors of quality of life, global outcome, and post-concussion symptoms in the first year following mild traumatic brain injury
3/24/2016 ... Employment status was the most crucial associated factor for QoL in
individuals with mTBI at the 1-year follow-up.
Ongoing daytime behavioural problems in university students following childhood mild traumatic brain injury
3/25/2016 ... Results suggest that university students with a history of mild TBI are more likely to experience certain ongoing daytime behavioral problems, which are likely to negatively influence their academic functioning.
Balance and mobility in clinically recovered children and adolescents after a mild traumatic brain injury
03/31/2016 ... Children with mTBI performed worse on all balance scales (p< 0.05). Gait parameters were significantly better for the controls.
The impact of symptomatic mild traumatic brain injury on complex everyday activities and the link with alterations in cerebral functioning
4/1/2016 ... Results of this exploratory study suggest that reduced independence in complex everyday activities in symptomatic mTBI may be at least partly explained by a decrease in brain activation in the prefrontal cortex, abnormal ERP, or slower reaction times on working memory tasks.
4/7/2016 ... TBI at time of injury demonstrated a nonsignificant trend toward higher rates of PTSD at 3 months and significantly predicted PTSD at 6 months after injury.
Prevalence of mental health conditions after military blast exposure, their co-occurrence, and their relation to mild traumatic brain injury
4/8/2016 ... These findings support that psychiatric conditions beyond PTSD are common after military combat deployment with blast exposure.
4/13/2016 ... mTBI is associated with the severity of sub-clinical coronary atherosclerosis and independently predicts CV mortality.
4/25/2016 ... While prevalence of headache is consistently high over the first year after injury, rate of depression increased over the first year for those who were followed.
5/3/2016 ... Mental fatigue of MTBI patients persists for more than 12 months, and can be mitigated partly within the first year after injury.
5/12/2016 ... Although some people make a spontaneous recovery after mTBI, nearly half continue to experience persistent symptoms linked to their injury.
5/31/2016 ... Functional interactions of the executive and salience networks were
related to emotion regulation and complaints after mTBI, with a key role for the
bilateral frontal network.
6/15/2016 ... Findings underline that clinicians and researchers should be aware of recovery for all mTBI patients, to prevent a forgotten minority.
6/21/2016 ... Recovery after MTBI in older adults may be associated more with psychosocial than with biomedical or injury-related factors.
Ongoing daytime behavioural problems in university students following childhood mild traumatic brain injury
7/13/2016 ...Our results suggest that university students with a history of mild TBI are more likely to experience certain ongoing daytime behavioural problems, which are likely to negatively influence their academic functioning in tertiary education.
8/1/2016 ... Even children with relatively mild early TBI experience long-term functional impairments, particularly in the context of less favorable home environments.
9/7/2016 ...The results revealed diverse psychosocial problem areas across the sample, the most common of which were somatic and cognitive complaints, compromised insight, and a naively optimistic self-perception.
9/13/2016 ... Our findings underline that clinicians and researchers should be aware of recovery for all mTBI patients, preventing their transition into a forgotten minority.
9/28/2016 ... This study identified social support as the most powerful predictor for QOL.
9/29/2016 ...SI is common 3 months after mTBI, and appears more at 6 month follow up.
10/25/2016 ...These results suggest that saccadic impairment may reflect chronic effects of mild TBI that conventional measures are unable to detect.
Patients "At Risk" of Suffering from persistent complaints after mild traumatic brain injury: The role of coping, mood disorders, and post-traumatic stress
11/7/2016 ... We conclude that in addition to reported complaints, psychological factors such as coping style, depression, anxiety, and post-traumatic stress symptoms had the highest predictive value and should be taken into account in the identification of at-risk patients for future treatment studies.
Increased cerebrospinal fluid neurofilament light proteins and reduced amyloid β were observed in patients with PCS, suggestive of
axonal white matter injury and amyloid deposition.
What's wrong with me? seeking a coherent understanding of recovery after mild traumatic brain injury
12/14/2016 ... Participants regardless of recovery status identified the importance of having a coherent understanding of their injury and recovery.
Reduced power spectra of heart rate variability are correlated with anxiety in patients with mild traumatic brain injury
1/3/2017 ... A correlation analysis indicated that anxiety was negatively significantly correlated with low- and high-frequency power at the 6th week.
Mild Traumatic Brain Injury: Longitudinal study of cognition, functional status, and post-traumatic symptoms
1/12/2017 ... While most neuropsychological and functional differences abate by one year, reporting 3 or more post traumatic symptoms remain for about half of individuals.
2/14/12 ... Only by employing complex machine-learning techniques to decipher repeated advanced brain scans were researchers at NewYork-Presbyterian/Weill Cornell able to provide evidence that a patient with a severe brain injury could, in her way, communicate accurately.
3/30/2012 ... These results suggest that mild traumatic brain injury predisposes the brain toward heightened fear learning during stressful postinjury events and provides a potential molecular mechanism by which this occurs.
4/11/2012 ... Scientists report that they have mapped the physical architecture of intelligence in the brain.
New stem cell found in brain: Finding could be key to developing methods to heal and repair brain injury
4/24/2012 ... Researchers at Lund University in Sweden have discovered a new stem cell in the adult brain. These cells can proliferate and form several different cell types -- most importantly, they can form new brain cells.
5/9/2012 ... This study found no significant association between sex and mortality in either Victoria or Hong Kong and does not support the concept that females have better outcomes after traumatic brain injury.
5/17/2012 ... New study shows first case series of chronic traumatic encephalopathy in blast-exposed military service personnel and mechanism of injury in blast neurotrauma.
5/23/2012 ... The research uses a radically new patented technology highly effective in reducing the condition.
6/5/2012 ... Like emergency workers rushing to a disaster scene, cells called microglia speed to places where the brain has been injured, to contain the damage by 'eating up' any cellular debris and dead or dying neurons.
6/11/2012 ... Researchers have found that concussion victims have unique spatial patterns of brain abnormalities that change over time.
Hypothalamic-pituitary dysfunction following traumatic brain injury affects functional improvement during acute inpatient rehabilitation
6/25/2012 ... These findings suggest the importance of testosterone and insulin growth factor-1 activity in the early stages of physical and cognitive rehabilitation.
Progressive brain atrophy in patients with chronic neuropsychiatric symptoms after mild traumatic brain injury
8/2/2012 ... Patients had abnormally rapid progressive atrophy in several brain regions and the rate of atrophy was associated with inability to return to work.
8/7/2012 ... Postconcussive symptom severity was linked to abnormal regional connectivity within nearly every brain network identified, particularly anterior cingulate.
Chronic traumatic encephalopathy: neurodegeneration following repetitive concussive and subconcussive brain trauma
8/8/2012 ... Chronic Traumatic Encephalopathy (CTE) is a neurodegenerative disease thought to be caused, at least in part, by repetitive brain trauma, including concussive and subconcussive injuries.
8/13/2012 ... Given the high incidence of TBI, this may have significant resource implications for Endocrinology services but, on the other hand, patients with PTHP may receive suboptimal rehabilitation unless the underlying hormone deficiency is identified and treated.
8/17/2012 ... The presence of a postconcussion syndrome (PCS) induces substantial socio-professional troubles in mild traumatic brain injury (mTBI) patients.
8/20/2012 ... MTBI-induced differences in
working memory functional activity were observed even though differences in behavioral performance between MTBI patients and controls were absent, which suggests that this approach may increase sensitivity to MTBI compared with neuropsychological evaluation alone.
8/22/2012 ... It is presently unknown whether dementia in TBI survivors is pathophysiologically similar to Alzheimer disease, CTE, or some other entity.
8/23/2012 ... whole-brain functional connectivity is altered early
(within 4 weeks) after MTBI, suggesting that changes in functional networks underlie the cognitive deficits and postconcussive complaints reported by patients with MTBI.
8/30/2012 ... Following the primary mechanical insult TBI results in delayed secondary injury events due to neurochemical, metabolic and cellular changes that account for many of the neurological deficits observed after TBI.
Longitudinal diffusion tensor imaging and neuropsychological correlates in traumatic brain injury patients
8/31/2012 ... The results of this study showing progressive WM deterioration for several years post-injury contribute to a growing literature supporting the hypothesis that TBI should be viewed not as an isolated incident but as a prolonged disease state.
10/25/2012 ... Investigation of the relationship between hemoglobin (Hgb) and brain tissue oxygen tension (PbtO(2)) after severe traumatic brain injury (TBI) and to examine its impact on outcome.
11/13/2012 ... Lowered white matter integrity may be more important in the pathophysiology of NPD than indices of gray matter or white matter atrophic changes, macroscopic lesions, and injury severity.
11/16/2012 ... Findings suggested that iron and ferritin might be involved in the secondary brain injury and could be therapeutic targets for patients with TBI.
12/6/2012 ... Gene expression of specific brain biomarkers offers the possibility to shed light on the difficult molecular pathways of traumatic brain injury (TBI) and may be useful to estimate the age of trauma.
1/2/2013 ... These findings could make the cerebellum an important target area to study the expression changes after TBI.
1/9/2013 ... Based on these preclinical
results, the selective inhibition of MCU may be a new strategy for neuroprotection in TBI patients.
1/22/2013 ... These results demonstrate that prolonged microglial activation is a feature of traumatic brain injury, but that the neuroinflammatory response returns to control levels after several years.
1/25/2013 ... The frequent association of chronic traumatic encephalopathy with other neurodegenerative disorders suggests that repetitive brain trauma and hyperphosphorylated tau protein deposition promote the accumulation of other abnormally aggregated proteins including TAR DNA-binding protein 43, amyloid beta protein and alpha-synuclein.
2/15/2013 ... mTBI is associated with increased venous drainage through secondary
pathways. This reflects higher outflow impedance, which may explain the finding
of reduced intracranial compliance.
2/27/2013 ... These data present striking evidence of persistent inflammation and ongoing white matter degeneration for many years after just a single traumatic brain injury in humans.
Are there cognitive and neurobehavioural correlates of hormonal neuroprotection for women After TBI?
3/4/2013 ... This study examined possible cognitive correlates of hormonal neuroprotection following traumatic brain injury (TBI) using archival neuropsychological findings for 1563 individuals undergoing acute TBI rehabilitation between 1989 and 2002.
Proton MR spectroscopy correlates diffuse axonal abnormalities with post-concussive symptoms in mild traumatic brain injury
3/11/2013 ... Global WM NAA, therefore, showed sensitivity to the TBI sequelae
associated with common PCS in individuals with mostly normal neuroimaging as well
as GCS scores.
3/28/2013 ... Contusion alone did not worsen the prognosis of patients in
short-term follow-up and did not cause neurosurgical interventions.
Neural correlates of apathy revealed by lesion mapping in participants with traumatic brain injuries
4/10/2013 ... Results revealed that increased apathy symptoms were associated
with brain damage in limbic and cortical areas of the left hemisphere including
the anterior cingulate, inferior, middle, and superior frontal regions, insula, and supplementary motor area.
5/7/2013 ... Pain in mTBI patients was associated with more rapid qEEG activity, mostly during REM sleep, suggesting that pain is associated with poor sleep and is a critical factor in managing post-concussion symptoms.
6/14/2013 ... Persistent coma after severe brain injury is associated with bilateral thalamic ischemia.
6/27/2013 ... Late-onset IH is a relatively common clinical condition in the pediatric population with severe TBI (present in 13% of the cases in our series), and the presence of a Marshall III CT scan at admission is a significant risk factor for this condition.
Human mild traumatic brain injury decreases circulating branched-chain amino acids and their metabolite levels
7/2/2013 ... Changes suggest alteration of BCAA metabolism after TBI may contribute to decreased energy production and neurotransmitter synthesis and may contribute to TBI pathophysiology.
7/3/2013 ... Diffusion tensor imaging parameters suggesting disruptions in white matter in the CC may be implicated in impaired performance, both in terms of cognitive tasks and reaction time, after TBI.
9/20/2013 ... The potent systemic inflammatory response induced by TBI, especially the intensively increase oxidative activity of circulating leukocytes, mainly neutrophils, may lead to a systemic damage, dysfunction/damage of bystander tissues/organs and even further exacerbate secondary local damage.
10/4/2013 ... DTI changes in major white matter tracts persist up to 5 years after severe traumatic brain injury and are most pronounced in the corpus callosum and corona radiata.
10/11/2013 ... These results support that interstitial generation of potentially toxic Aβ species may occur following human TBI, particularly related to axonal injury.
Resting-state functional magnetic resonance imaging activity and connectivity and cognitive outcome in traumatic brain injury
10/17/2013 ... Increased ALFF is related to better cognitive performance in chronic TBI.
10/30/2013 ... These findings suggested that iron and ferritin might be involved in the secondary brain injury and could be therapeutic targets for patients with TBI.
11/22/2013 .. Neuroprotective effects of estradiol on brain edema, BBB permeability, and neurological scores are mediated through both ERα and ERβ.
12/2/2013 ... Screening pituitary function after TBI for five years is important, especially in patients with mild TBI.
1/17/2014 ... Persistent coma after severe brain injury is associated with bilateral thalamic ischemia.
2/4/2014 ... Secondary increases in serum levels of S100B, even as low as ≥0.05 μg/L, beyond 48 h after TBI are strongly correlated to the development of clinically significant secondary radiological findings.
3/19/2014 ... These results demonstrate that prolonged microglial activation is a feature of traumatic brain injury, but that the neuroinflammatory response returns to control levels after several years.
7/14/2014 ... Analyzing the structural brain network connectivity provides new insights into understanding cognitive control changes following brain injury.
7/22/2014 ... These results support the conclusion that Val/Met genotypes preserve general cognitive functioning, whereas Val/Val genotypes are largely susceptible to TBI.
7/28/2014 ... Traumatic brain injury was associated with risk of stroke and poststroke mortality.
7/29/2014 ... The results suggest that impairments of self-awareness after traumatic brain injury result from breakdown of functional interactions between nodes within the fronto-parietal control network.
8/14/2014 ... Our results suggest that the relationship between TBI-related aggression and the dopaminergic system is modulated by lesion location.
10/2/2014 ... Relative sparing of the uncinate fasciculus is seen in female compared with male patients after mTBI.
10/16/2014 ... Volumetric reduction to specific regions, including parietal, temporal and occipital lobes, after a mild TBI may underlie the susceptibility of these patients developing major depression.
Right frontal pole cortical thickness and social competence in children with chronic traumatic brain injury
5/6/2015 ... Direct effect of right frontal pole cortical thickness on social competence was significant.
6/8/2015 ... Results indicated that white matter volume loss can be a superior predictor of recovery and a crucial factor driving clinical outcome in functions involving a broad network such as Verbal Fluency.
6/12/2015 ... TBI patients' brains were estimated to be older than their chronological age.
7/8/2015 ... The frequency of hypopituitarism after TBI is between 15-50% of the patients in most studies.
7/21/2015 ... We found no evidence for an association between structural brain injury and malignant astrocytic tumors within the first 5 years of follow-up.
8/12/2015 ... TBI induces a widespread activation of brain microglia which affects all cortical areas, including those distant from the contusion site.
8/28/2015 ... Hematoma enlargement may be a direct contributor to death and disability in patients with TBI at 6 months.
9/28/2015 ... This study provides evidence of cortical thinning in the context of chronic blast-related mild and moderate TBI in military veterans who have co-morbid psychiatric symptoms.
12/3/2015 ... Patients with MVA and those with post-traumatic
seizures, intracranial hemorrhage, petechial brain hemorrhages, and/or focal cortical contusions are at particular risk for serious pituitary dysfunction.
1/21/2016 ... Parenchymal brain lacerations may be related to abusive injury mechanisms.
2/5/2016 ... Military personnel who report multiple TBIs have long-term elevations in total tau concentration.
2/24/2016 ... Our results suggest that PTHP is a common condition amongst sufferers of TBI, and appropriate measures should be taken to detect and manage it.
Altered amygdala connectivity in individuals with chronic traumatic brain injury and comorbid depressive symptoms
2/25/2016 ... Results suggest that amygdala connectivity may be a potentially effective neuroimaging biomarker for comorbid depressive symptoms in chronic TBI.
2/26/2016 ... A sex-specific DA-pathway GRS may be a valuable tool when predicting cognitive recovery post-TBI.
The female advantage: sex as a possible protective factor against emotion recognition impairment following traumatic brain injury
8/11/2016 ... These findings suggest that sex may serve as a protective factor for social impairment following TBI.
Persistent hypogonadotropic hypogonadism in men after traumatic brain injury: Temporal hormone profiles and outcome prediction
10/31/2016 ...PHH status in men predicts poor outcome after severe TBI, and PHH can accurately be predicted at 12 to 16 weeks.
12/5/2016 ... Perturbations in pituitary function continue to occur during the first year after TBI and SAH, but only a few patients need replacement therapy.
12/21/2016 ... The risk of developing endocrine dysfunction after TBI increased during the entire 5-year follow-up period.
2/3/12 ... Patients with minor head injury who present over 4 h post-insult exhibit a similar risk of intracranial pathology to those presenting within 4 h.
Effect of posttraumatic thyroid hormone levels on severity and mortality of patients with severe traumatic brain injury
2/15/12 ... The aim of this study is to evaluate the effect of thyroid hormones after traumatic brain injury in the severity and mortality and gain a clue in brain injury prognosis.
2/24/12 ... The study indicated that cognitive recovery in severe TBI subjects had not been completed within 3-13 months post-injury, but also that the neural degeneration in severe TBI continues long after the head trauma.
3/6/2012 ... A recent study shows that physiological problems stemming from a concussion may continue to present in the patient even after standard symptoms subside.
Characteristics associated with satisfaction with life 1 year post traumatic brain injury in a population of Hispanic individuals
3/15/2012 ... Focusing rehabilitation efforts on improving cognition and vocational skills may improve SWLS in Hispanics 1 year post-TBI.
3/20/2012 ... Low initial GCS, worst first CT scan, intracranial hypertension and acute kidney injury determined hospital mortality in severe TBI patients.
Association of initial CT findings with quality-of-life outcomes for traumatic brain injury in children
3/26/2012 ... Associations exist between findings from the initial noncontrast head CT and quality of life score 12 months after injury in children with TBI.
Factors predicting functional and cognitive recovery following severe traumatic, anoxic, and cerebrovascular brain damage
3/27/2012 ... Patients with traumatic brain injury achieved greater functional and cognitive improvements than patients with cerebrovascular and anoxic ABI.
3/28/2012 ... The strongest and most consistent factors associated with independence in mobility and self-care were fewer comorbid conditions, no difficulty of access to home modification services and home support services, male gender, younger age at time of injury, and shorter acute care length of stay.
3/29/2012 ... Our findings suggest a positive correlation between TBI and the relatively short-term development of malignant neoplasms of the brain.
Glucose variability negatively impacts long-term functional outcome in patients with traumatic brain injury
4/20/2012 ... Glucose variability was significantly associated with poorer long-term functional outcome in patients with TBI as measured by the GOSE score.
Relationship of caregiver and family functioning to outcomes after postacute rehabilitation for traumatic brain injury
4/30/2012 ... Caregiver distress should be accounted for in studies investigating
the effectiveness of postacute rehabilitation after TBI.
5/4/2012 ... In this review, we examine the various factors that must be taken into account in the search for a reliable non-invasive biomarkers in traumatic brain injury and their role in the diagnosis and outcome evaluation.
5/25/2012 ... A relation between GFAP with imaging studies and outcome (determined by RTW) was found in contrast to S100B. As the positive predictive value of GFAP is limited in this category of TBI patients, this biomarker is not suitable for prediction of individual patient outcome.
6/6/2012 ... Hispanic ethnicity is positively associated with higher mortality risk among veterans clinically diagnosed with traumatic brain injury.
6/13/2012 ... Contrary to expectations, children injured in middle childhood demonstrated the poorest outcomes; this age potentially coincides with a critical period of brain and cognitive development.
6/18/2012 ... Since both the International Mission on Prognosis and Analysis of Clinical Trials and the Corticoid Randomisation After Significant Head injury prognostic models show good generalizability to more recent data, they are valid instruments to quantify prognosis in traumatic brain injury.
6/29/2012 ... Head turning, together with or immediately followed by visual pursuit and fixation, proved to be clinically significant variables associated with recovery from vegetative state to higher states of consciousness
beyond minimally conscious state.
7/9/2012 ... Recent genetic studies have revealed emerging aspects and extended the existing knowledge regarding the pathogenesis of neurotrauma and the genetic influence on phenotypic diversity.
7/11/2012 ... After adjusting for sociodemographic characteristics, the hazard of being
diagnosed with malignant brain tumors during the 3-year follow-up period was 4.67 (95% CI: 1.84-11.83) times greater for those who sustained a TBI than for patients in the comparison cohort.
Return to driving after severe traumatic brain injury: increased risk of traffic accidents and personal responsibility
7/16/2012 ... The ability to drive is frequently compromised after severe TBI. Specific rehabilitation of this complex activity should be a main goal of social
reintegration programs in this population.
7/30/2012 ... Patients with TBI with psychiatric symptoms and impaired cognitive functioning at hospital discharge are at the highest risk of long-term unemployment. These factors should be the focus of vocational rehabilitation.
8/29/2012 ... The complexity of intracranial pressure assessed by multiscale entropy was significantly associated with outcome in patients with brain injury.
9/4/2012 ... Mortality at 1-year post-TBI is accurately predicted by the combination of GFAP and S100B concentration and clinical and radiological characteristics at admission or in the acute post-injury period.
9/13/2012 ... Global handicap and impairments of executive functions are independent significant predictors of caregiver burden 1 year after TBI.
Recovery of cognitive function during comprehensive rehabilitation after severe traumatic brain injury
9/17/2012 ... The consolidation of functional recovery in patients with traumatic brain injury requires time and adequate training, and discharge is not recommended until cognitive improvement is established.
Are there gender differences in cognitive function, chronic stress, and neurobehavioral symptoms after mild-to-moderate traumatic brain injury?
9/20/2012 ... Overall, this study only found gender differences on verbal memory composite scores, whereas the remaining cognitive tasks, neurobehavioral symptoms, and chronic stress did not indicate gender differences.
9/27/2012 ... More than 2 years after injury, polytraumatized patients with and without TBI suffer from a reduction in functional outcome and quality of life, but TBI patients are doing importantly worse.
How important is resilience among family members supporting relatives with traumatic brain injury or spinal cord injury?
10/5/2012 ... These results are consistent with resilience theories which propose that people with high resilience are more
likely to display positive adaptation when faced by significant adversity.
10/10/2012 ... Contusion alone did not worsen the prognosis of patients in short term follow up and did not cause neurosurgical interventions.
Trends in outcomes and hospitalization costs among traumatic brain injury in adult patients in the United States
10/15/2012 ... Although the number of TBI admissions was reduced, a significant increase in average hospitalization charges and in-hospital mortality rate was observed in 2006-2007 compared with 1993-1994.
10/22/2012 ... Mortality and morbidity due to brain injury in the elderly population is a growing clinical problem: among older patients, those >70 years have a considerably higher risk both in terms of mortality and morbidity.
10/30/2012 ... Creatinine was found an independent predictor of TBI outcome.
The effect of blood alcohol level and preinjury chronic alcohol use on outcome from severe traumatic brain injury in hispanics, anglo-Caucasians, and african-americans
11/1/2012 ... Ethnic differences in blood alcohol levels within our severe traumatic brain injury sample mirrored ethnic drinking patterns observed in the general population, with Hispanics having the highest BALs.
11/5/2012 ... The findings indicate that consideration of cognitive ability, rather than reliance on demographic and injury severity variables, provide a more accurate representation of functional outcome over the first year postinjury.
'Long' pressure reactivity index (L-PRx) as a measure of autoregulation correlates with outcome in traumatic brain injury patients
11/7/2012 ... L-PRx correlates with the 6-month outcome in TBI patients.
Relationship between cognitive and motor performance in physically well-recovered men with traumatic brain injury
11/15/2012 ... Apart from the theoretical relevance, the finding of an association between cognitive and motor performance may have clinical relevance with regard to rehabilitation.
11/21/2012 ... Serum IL-10 levels may be a useful marker for severe TBI prognosis.
Inflammasome proteins in cerebrospinal fluid of brain-injured patients as biomarkers of functional outcome
11/27/2012 ... NALP-1 inflammasome proteins are potential biomarkers to assess TBI severity, outcome, and the secondary injury mechanisms impeding recovery, serving as adjuncts to clinical predictors.
11/28/2012 ... Results suggest that pressure time dose measurement of intracranial pressure may be used to predict outcome in severe traumatic brain injury and may be a candidate biomarker in this disease.
11/29/2012 ... Results suggest that preinjury depressed mood and low resilience are significant contributors to the severity of postinjury anxiety and postconcussion symptoms, even after accounting for effects of other specific host factors.
11/30/2012 ... Data suggest that gender does not play a role in the outcome of patients with acute traumatic brain injury.
12/4/2012 ... Acute care outcomes for intracranial injuries have been improving at a cost of $1,071 per patient per year.
Post-traumatic amnesia predicts intelligence impairment following traumatic brain injury: a meta-analysis
12/14/2012 ... PTA duration is a valuable predictor of intelligence impairment
12/20/2012 ... Mortality rates associated with moderate and severe injuries may be attributed to complications, chronic disease prevalence, conservative management techniques or the consequences of biological ageing.
12/26/2012 ... Multiple cognitive functions are associated with initial
impairment and partial recovery of FC in moderate-to-severe TBI patients. In
particular, arithmetic, working memory, and executive function skills appear
critical to recovery of FC in TBI.
12/27/2012 ... Life expectancy was shortened an average of 6.7 years.
Traumatic brain injury with and without late posttraumatic seizures: What are the impacts in the post-acute phase: A NIDRR Traumatic Brain Injury Model Systems study
12/28/2012 ... It does appear that the development of LPTS following a TBI is
associated with poorer functional and psychosocial outcomes in the first 5 years
Mortality and long-term functional outcome associated with intracranial pressure after traumatic brain injury
1/7/2013 ... Average ICP in the first 48 h of monitoring was an independent
predictor of mortality and of a composite endpoint of functional and
neuropsychological outcome at the 6-month follow-up in moderate or severe TBI patients.
Plasma high-mobility group box 1 levels and prediction of outcome in patients with traumatic brain injury
1/8/2013 ... The prognostic value of HMGB1 was similar to that of Glasgow Coma Scale
score for 1-y clinical outcomes.
1/16/2013 ... Traumatic brain
injury in conjunction with diabetes mellitus is associated with an almost
1.5-fold increased mortality while compared to patients with isolated TBI without diabetes mellitus.
1/17/2013 ... Impaired self-awareness remains evident more than 5 years after TBI.
Role of early cell-free DNA levels decrease as a predictive marker of fatal outcome after severe traumatic brain injury
1/31/2013 ... In summary we showed that severe TBI is associated with elevated
cf-DNA levels and we propose that cf-DNA decrease during the first 24h may
predict patient outcome.
2/4/2013 ... Patients with mental disorders have an increased risk of TBI.
Intensity of psychiatric medication is associated with increased post-injury
2/7/2013 ... Low initial GCS, worst first CT scan, intracranial hypertension and
AKI determined hospital mortality in severe TBI patients.
2/8/2013 ... Examining the influence of polymorphisms on TBI
outcome has the potential to contribute to an understanding of variations in TBI
outcome, aid in the triaging and treatment of TBI patients, and ultimately lead to targeted interventions based on genetic profiles.
2/12/2013 ... Systolic blood pressure values above 160 mm Hg before arrival in the hospital worsen the outcome of trauma patients with TBI.
2/19/2013 ... Age, LOS, alcohol and drug abuse, motor vehicle collision and lower GCS at admission were associated with greater physical disabilities and functional impairment at discharge.
2/22/2013 ... Living arrangements (such as
intermediate settings) may better support social participation in individuals
Examination of outcome after mild traumatic brain injury: The contribution of injury beliefs and Leventhal's Common Sense Model
3/13/2013 ... Consistent with Leventhal's model, participant beliefs about their injury and recovery had significant associations with outcome over time.
The potential utility of blood-derived biochemical markers as indicators of early clinical trends following severe traumatic brain injury
3/20/2013 ... In conjunction with other clinical, physical, and radiologic evidence, blood-derived biochemical markers may serve to enhance prediction of early clinical trends following severe TBI.
The influence of chronic cigarette smoking on neurocognitive recovery after mild traumatic brain injury
4/5/2013 ... For sMTBI, over the AP1-AP2 interval, greater lifetime duration of smoking and pack-years were related to significantly less improvement on multiple domains.
4/11/2013 ... Plasma copeptin level represents a novel biomarker for predicting 6-month clinical outcome in children with TBI.
4/16/2013 ... Among 6-month survivors, accounting for nonhead injuries resulted in a nonsignificant effect of TBI on long-term mortality.
4/29/2013 ... Detection of β-amyloid oligomers may someday become a useful clinical tool for determining injury severity and neurological outcomes in patients with TBI.
The association of compensation and long term health status for people with severe traumatic injuries
5/10/2013 ... Financial compensation may have a small negative association with recovery, even for people with severe traumatic injury.
5/14/2013 ... Low cognitive function, intoxications, and factors related to low
socioeconomic status were strong independent risk factors for mild traumatic
brain injuries in men.
5/15/2013 ... The results of this study suggest that cognitive reserve may mediate recovery after a moderate or severe TBI.
5/17/2013 ... Despite a strong negative selection, a substantial proportion of
severe TBI patients with DOC achieves functional improvements or at least emerge
from MCS within the inpatient rehabilitation phase.
The effect of environmental barriers on community integration for individuals with moderate to severe traumatic brain injury
5/20/2013 ... Environmental barriers should be addressed in rehabilitation and considered in policy development for people with traumatic brain injury.
5/21/2013 ... Premorbid demographic and baseline neurocognitive factors should be taken into account prior to comprehensive treatment of mild traumatic brain injury, as they can influence long-term outcomes.
5/28/2013 ... Cognitive screening can identify the long-term impact of TAI identified by conventional MRI, used as a routine clinical technique. For rehabilitation and for insurance-related matters, these injuries must be taken seriously, as a deterioration over time might occur.
Factors predicting functional and cognitive recovery following severe traumatic, anoxic, and cerebrovascular brain damage
6/7/2013 ... Patients with traumatic brain injury achieved greater functional and cognitive improvements than patients with cerebrovascular and anoxic ABI.
Serum Adhesion Molecules, Outcome and Neuro-psychological Function in Acute Traumatic Brain Injury Patients
6/10/2013 ... Serum adhesion molecules are not specific for predicting outcome in patients with TBI. However, higher mean levels of these molecules on admission may imply more severe inflammatory response causing secondary brain injury and worse neurosychological function.
6/17/2013 ... HRQL appears to be relatively stable between 1 and 2 years after injury.
6/18/2013 ... Maximizing EE in the post-acute stages of TBI may improve long-term outcomes for the individual, their family and society.
7/1/2013 ... There is substantial variation in patterns of HSU following severe TBI.
7/8/2013 ... Despite the lower functional status, patients with TBI displayed better functional recovery than patients with BT.
Predictive value of S-100β protein for prognosis in patients with moderate and severe traumatic brain injury
7/9/2013 ... After moderate or severe traumatic brain injury, serum S-100β protein concentrations are significantly associated with unfavourable prognosis in the short, mid, or long term.
Specialized early treatment for persons with disorders of consciousness: Program components and outcomes
7/22/2013 ... Persons with DOC due primarily to traumatic etiology who receive specialized early treatment that includes acute medical care and 90+ minutes of daily rehabilitation are likely to show improved consciousness and body function; more than half may transition to mainstream inpatient rehabilitation.
7/23/2013 ... Substantial proportions of patients admitted to acute inpatient rehabilitation prior to following commands recover independent functioning over as long as 5 years.
Premorbid personality characteristics and attachment style moderate the effect of injury severity on occupational outcome in traumatic brain injury
7/26/2013 ... Findings offer preliminary support for premorbid personality features as another relevant reserve construct in predicting outcome in this population.
8/9/2013 ... Hispanic children with TBI report larger and long-term reductions in their quality of life, participation in activities, communication, and self-care abilities compared with NHW children.
8/14/2013 ... Study findings suggest that interventions that reduce acute metabolic crisis may lead to improved functional outcomes for traumatic brain injury survivors.
The association of compensation and long-term health status for people with severe traumatic injuries
8/16/2013 ... Financial compensation may have a small negative association with recovery, even for people with severe traumatic injury.
8/23/2013 ... In this large cohort, TBI is associated with ischemic stroke, independent of other major predictors.
Predictive factors for 1-year outcome of a cohort of patients with severe traumatic brain injury (TBI)
9/5/2013 ... Age, education and injury severity are independent predictors of global disability and return to work 1 year after a severe TBI.
Influence of ATP-Binding cassette polymorphisms on neurological outcome after traumatic brain injury
9/17/2013 ... Patients homozygous for the T- allele of ABCB1 rs1045642 or the G allele of ABCC1 rs4148382 were found to have better outcome after severe TBI.
Longitudinal follow-up of patients with traumatic brain injury: Outcome at 2, 5, and 10-years post-injury
9/23/2013 ... Overall, problems that were evident at 2 years post-injury persisted until 10 years post-injury.
9/25/2013 ... Findings indicate that mitochondrial DNA variation may impact patient outcomes after a TBI potentially by influencing mitochondrial function and that sex of the patient may be important in evaluating these associations in future studies.
9/30/2013 ... Long-term survival prognosis in TBI depends on age, sex, and disability.
Unexpected recovery of function after severe traumatic brain injury: The limits of early neuroimaging-based outcome prediction
10/3/2013 ... MRI data should be interpreted with caution when prognosticating for patients in traumatic coma. Recovery of consciousness and community reintegration are possible even when extensive traumatic axonal injury is demonstrated by early MRI.
10/10/2013 ... Specific chronic diseases strongly influenced postdischarge mortality after traumatic brain injury. Low socioeconomic status as measured by the type of insurance elevated the risk of death.
10/15/2013 ... Prehospital neurologic deterioration is an independent predictor of worse hospital outcome and higher resource use in patients with TBI.
10/24/2013 ... A substantial proportion of severe TBI patients with DOC achieve functional improvements or at least emerge from MCS within the inpatient rehabilitation phase.
10/31/2013 ... It appears that individuals who are married or cohabiting and productive had higher life satisfaction.
11/12/2013 ... fFndings suggest a history of LBW influences the recovery trajectory following childhood TBI.
11/27/2013 ... In contrast to clinical serum hormone studies, higher CSF E2/T ratio was associated with better outcome.
12/6/2013 ... This study shows that severe extra cranial concomitant injuries are associated with a poor long term functional outcome even in the mild traumatic brain injury patients and therefore need to be addressed early in the rehabilitation of this group of patients.
12/11/2013 ... Early ECF NO x concentrations are of prognostic value after TBI.
Increased levels of serum IL-18 are associated with the long-term outcome of severe traumatic brain injury
12/13/2013 ... IL-18 may contribute to the long-term outcome and neurodegeneration in TBI patients.
Can baroreflex sensitivity and heart rate variability predict late neurological outcome in patients with traumatic brain injury?
12/20/2013 ... HRV and BRS measures in TBI patients during intensive care treatment, including sedative, analgesic, and vasoactive drugs, may identify patients with poor late neurological outcome.
Comparative effectiveness of traumatic brain injury rehabilitation: Differential outcomes across TBI Model Systems centers
12/27/2013 ... There are significant differences in functional outcomes of TBI patients across rehabilitation centers.
1/3/2014 ... Thoracic injury diagnosed by CT has a negative impact on the 30-day mortality and functional outcome of TBI patients.
1/6/2014 ... Results confirm the big impact of acquired brain injury on the career path two years later, in their interaction with their environment and in their level of independence. One of the factors that explain this impact is the memory deficits.
1/8/2014 ... Symptom pressure and global functioning in the sub-acute phase of traumatic brain injury and psychological distress in the post-acute phase are important for health-related quality of life at 12 months post-injury.
1/10/2014 ... Motor deficits appear to have smaller significance for participation in this late state, while emotional and social factors play a major role.
Hypothalamic-pituitary dysfunction following traumatic brain injury affects functional improvement during acute inpatient rehabilitation
1/27/2014 ... These findings suggest the importance of testosterone and insulin growth factor-1 activity in the early stages of physical and cognitive rehabilitation.
2/6/2014 ... The serum levels of calcium on day three could be useful for the prediction of mortality in patients with moderate and severe TBI.
2/10/2014 ... No strong evidence was found that vocational outcomes after TBI could be predicted or improved.
Subjective impact of traumatic brain injury on long-term outcome at a minimum of 10 years after trauma
2/13/2014 ... The severity of TBI significantly influenced the subjective social and living conditions.
Do prolonged transport times for traumatic brain injury patients result in deteriorating physiology?
2/17/2014 ... The similarity between prehospital and ED vital signs, and lack of association between EMS interval and physiological deterioration, may support a strategy ofdirect transportation of TBI cases to specialist centers.
Differentiated patterns of cognitive impairment 12 months after severe and moderate traumatic brain injury
2/20/2014 ... Differentiating between patients with moderate and severe TBI yields a more accurate description of cognitive deficits and their improvement over time.
Acute alcohol intoxication, diffuse axonal injury and intraventricular bleeding in patients with isolated blunt traumatic brain injury
2/21/2014 ... Acute alcohol intoxication was not associated with type and number of DAI lesion, IVB and disability.
How does dysautonomia influence the outcome of traumatic brain injured patients admitted in a neurorehabilitation unit?
2/24/2014 ... Functional status is similar and PSH does not appear to influence recovery during the rehabilitation, although PSH patients are more likely to undergo psychoactive medications and special care is needed to approach their caregivers that perceive PSH as a complication for rehabilitation.
2/25/2014 ... Plasma adiponectin level may represent a novel biomarker for predicting clinical outcomes of traumatic brain injury.
2/26/2014 ... These results suggest that diagnosis threat may have a greater impact on psychological factors than on cognitive performance.
Reduced brain/serum glucose ratios predict cerebral metabolic distress and mortality after severe brain injury
3/5/2014 ... Reduced brain/serum glucose ratios, consistent with impaired glucose transport across the blood brain barrier, are associated with cerebral metabolic distress and increased mortality after severe brain injury.
3/6/2014 ... Pubescent female gender predicts reduced mortality following isolated, moderate-to-severe TBI.
3/10/2014 ... Posthospital programs using a multidisciplinary treatment approach achieved significant reduction in disability from program admission to discharge.
3/12/2014 ... These findings suggest that history of TBI with LOC may have important implications for health and psychological functioning after aTBI in community-based samples.
Prior history of traumatic brain injury among persons in the traumatic brain injury model systems national database
3/17/2014 ... Earlier life TBI may have important implications for rehabilitation after subsequent TBI, especially for anticipating behavioral health issues in the chronic stage of recovery.
3/18/2014 ... Substantial proportions of patients admitted to acute inpatient rehabilitation before following commands recover independent functioning over as long as 5 years.
Post-traumatic hypoxia is associated with prolonged cerebral cytokine production, higher serum biomarker levels and poor outcome in patients with severe traumatic brain injury
3/25/2014 ... We demonstrate for the first time that post-TBI hypoxia is associated with prolonged neuroinflammation, amplified extravasation of biomarkers, and poor outcome.
3/28/2014 ... The vast majority of this cohort returned to work within 2 months. Predictors of slower RTW included age, multiple bodily injuries, intracranial abnormality at the day of injury, and fatigue.
4/2/2014 ... Patients with stroke have an increased risk of TBI and in-hospital mortality after TBI.
Head trauma sustained under the influence of alcohol is a predictor for future traumatic brain injury
4/9/2014 ... Even head trauma without TBI under the influence of alcohol implies an elevated risk of subsequent TBI.
4/14/2014 ... The findings suggest that the cause of a TBI may assist in explaining some of the differences in the outcomes of people who have seemingly comparable injuries.
4/15/2014 ... Menstrual cycle phase and progesterone concentration at the time of mTBI affect 1-month quality-of-life and neurologic outcomes.
5/1/2014 ... Higher intellectual enrichment (estimated with education) reduces the negative effect of TBI on cognitive outcomes, thereby supporting the cognitive reserve hypothesis in persons with TBI.
Chronic alcoholism-mediated impairment in the medulla oblongata: a mechanism of alcohol-related mortality in traumatic brain injury?
5/7/2014 ... Chronic alcoholism induces significant synapse loss and axonal impairment in the medulla oblongata and renders the brain more susceptible to TBI.
5/20/2014 ... This study does not suggest that smoking affects the outcome of TBI.
Suicide, fatal injuries, and other causes of premature mortality in patients with traumatic brain injury
5/28/2014 ... Traumatic brain injury is associated with substantially elevated risks of premature mortality, particularly for suicide, injuries, and assaults, even after adjustment for sociodemographic and familial factors.
6/3/2014 ... Return to study was relatively successful; however, this was associated with the experience of fatigue and need for far greater effort, assistance and reduced study hours, and somewhat less overall satisfaction.
Prehospital risk factors of mortality and impaired consciousness after severe traumatic brain injury
6/9/2014 ... Mortality and impaired consciousness at 14 days do not have the same prehospital risk factors; prehospital hypotension and hypothermia is associated with mortality, and prehospital hypoxemia with impaired consciousness.
Contribution of psychological trauma to outcomes after traumatic brain injury: Assaults versus sporting injuries
6/24/2014 ... The findings suggest that the cause of a TBI may assist in explaining some of the differences in outcomes of people who have seemingly comparable injuries.
6/26/2014 ... Plasma adiponectin level may represent a novel biomarker for predicting clinical outcomes of traumatic brain injury.
Can baroreflex sensitivity and heart rate variability predict late neurological outcome in patients with traumatic brain injury?
6/30/2014 ... HRV and BRS measures in TBI patients during intensive care treatment, including sedative, analgesic, and vasoactive drugs, may identify patients with poor late neurological outcome.
Longitudinal follow-up of patients with traumatic brain injury: outcome at two, five, and ten years post-injury
7/9/2014 ... Overall, problems that were evident at two years post-injury persisted until 10 years post-injury.
7/10/2014 ... DTI changes in major white matter tracts persist up to 5 years after severe traumatic brain injury and are most pronounced in the corpus callosum and corona radiata.
Physical and psychological long-term outcome after traumatic brain injury in children and adult patients
7/23/2014 ... The sustained TBI impact seemed not to reduce the child's ability to overcome the suffered impairment.
US population estimates of health and social outcomes 5 years after rehabilitation for traumatic brain injury
7/25/2014 ... Significant mortality and morbidity were evident at 5 years postinjury.
7/31/2014 ... High CSF cortisol levels were associated with poor outcome.
Being single, unemployment prior to injury, blue collar occupation, lower Glasgow Coma Scale (GCS) score at hospital admission and greater length of post-traumatic amnesia (PTA) were significantly associated with being unemployed at 1, 2 and 5 years post-injury.
8/12/2014 ... There was significant variation between states in both rehabilitation discharge and inpatient mortality after adjusting for variables known to affect each outcome.
8/13/2014 ... Fever burden might be an independent predictor for prognosis of TBI.
High fever burden in the early stage of the disease course associated with TBI
could increase the risk of poor prognosis.
8/29/2014 ... Personality changes were an independent predictor of nRTW after severe TBI.
9/2/2014 ... Educational attainment was a robust independent predictor of 1-year DFR even when adjusting for other prognostic factors.
9/12/2014 ... Patients who started rehabilitation sooner and had a higher cognitive functionality at admission, showed the greatest increase in cognitive functionality gain percentage.
9/17/2014 ... Intoxication is an independent predictor for mortality in patients with severe TBI patients and is associated with higher complication rates.
Increased levels of interleukin-6, -8 and -10 are associated with fatal outcome following severe traumatic brain injury
9/24/2014 ... The findings indicate that increased IL-10, -8 and -6 levels may constitute an early predictor of unfavourable outcome in severe TBI patients.
9/25/2014 ... Having dependent children at the time of injury, higher education, and being in a blue collar occupation at time of injury were significant predictors of relationship stability.
9/30/2014 ... Only 44% of participants remained employed at each of the 3 years following TBI.
10/8/2014 ... The impact of medical comorbidities and type of insurance coverage predict disability above and beyond well-known prognostic variables.
Chronic inflammation after traumatic brain injury: Associations with outcome at 6-12 months postinjury
10/14/2014 ... Higher proinflammatory burden is significantly associated with outcome.
10/15/2014 ... Delays in rehabilitation admission were negatively associated with outcome.
10/20/2014 ... There was a 6-fold increase in the rate of hemorrhagic stroke following TBI compared with the pre-TBI period.
10/21/2014 ... Gender differences in executive dysfunction may not be as large or robust as some researchers argue.
10/23/2014 ... There is an increased risk of death for individuals with TBI requiring inpatient rehabilitation.
10/29/2014 ... Following sTBI, approximately two-thirds of survivors improve between 3 and 12 months postinjury and are satisfied with their life. Direct discharge from acute care to specialized rehabilitation appears to increase functional recovery.
10/30/2014 ... Slower recovery was associated with older age, longer coma, and interruptions to rehabilitation.
11/5/2014 ... These findings indicate that, at 3 months following mTBI, older adults are at risk of poor cognitive performance.
11/11/2014 ... Mental health trajectories of individuals with TBI differed as a function of race/ethnicity.
11/17/2014 ... Statistical analysis demonstrated profound age effect throughout the age interval covered.
11/24/2014 ... Older TBI patients who survive to discharge have a significant risk of death within 1 year.
Variable neuroendocrine-immune dysfunction in individuals with unfavorable outcome after severe traumatic brain injury
11/26/2014 ... Results suggest that unfavorable outcome after TBI may result from dysfunctional neuroendocrine-immune communication wherein an adequate immune response is not mounted or, alternatively, neuroinflammation is prolonged.
12/01/2014 ... The risk of death was increased for at least 10 years after severe TBI.
12/3/2014 ... Demographic, clinical, and financial characteristics influenced the likelihood of being discharged to rehabilitation.
12/5/2014 ... The data support the need for continuity of care, including ongoing emotional support, to cater to the complex and dynamic needs of the ABI population.
12/8/2015 ... There are significant differences in functional outcomes of TBI patients across rehabilitation centers.
12/11/2014 ... People experiencing recurrent TBIs are more likely to experience increased frequency and severity of post-concussion symptoms.
12/16/2014 ... Premorbid variables, especially pre-TBI felonies, were strongly linked to post-TBI criminal arrests.
12/19/2014 ... A positive THC screen is associated with decreased mortality in adult patients sustaining TBI.
12/22/2014 ... These findings may have important early triage and treatment implications.
Adverse outcomes among homeless adolescents and young adults who report a history of traumatic brain injury
12/29/2014 ... TBI occurs frequently among homeless young people and is a marker of adverse outcomes such as mental health difficulties, suicidal behavior, substance use, and victimization.
Social cognition and its relationship to functional outcomes in patients with traumatic brain injury
1/13/2015 ... The degree to which a patient can predict what others are thinking is an important measure that can estimate functional outcomes over 1 year following TBI.
1/20/2015 ... It is concluded that the sooner patients begin neurorehabilitation, the better their functional outcome.
1/23/2015 ... Low admission BAC (<2.3‰) was found to independently reduce risk of six-month mortality for patients with TBI, and a trend towards improved long-term neurological outcome was found for BAC-positive patients.
1/26/2015 ... Outcomes are difficult to separate from case mix factors that are associated with both outcome and allocation of treatment.
1/27/2014 ... Character strengths and virtues showed unique value in predicting physical health and disability.
2/4/2015 ... Significant decreases in the cost projections, i.e. rehabilitation-savings (RS), were found following rehabilitation for TBI.
A comparison of adult outcomes for males compared to females following pediatric traumatic brain injury
2/6/2015 ... Childhood TBI is associated with psychosocial problems in adulthood, regardless of injury severity. How deficits are expressed differs between the sexes.
2/18/2015 ... The cumulative effect of self-reported medical comorbidities and type of insurance coverage predict disability above and beyond well-known prognostic variables.
The main founding was that even HI without TBI carries an increased risk of future traumatic death.
3/13/2015 ... Cognitive impairments, unemployment, lack of long-term relationships, anxiety and PTSD are more substantial long-term problems following TBI.
3/17/2015 ... Low admission BAC was found to independently reduce risk of six-month mortality for patients with TBI, and a trend towards improved long-term neurological outcome was found for BAC-positive patients.
3/27/2015 ... Women with TBI reported that they did not receive care when needed (40%), particularly for emotional/mental health problems.
3/30/2015 ... History of TBI is common in older men, and is associated with increased risk of depression and cognitive impairment.
4/16/2015 ... Higher levels of independence in bladder management, bed-chair-wheelchair transfers and comprehension at admission were associated with lower risks of institutionalization at discharge.
4/20/2015 ... Insurance status appears to have an impact on short- and long-term outcomes to a greater degree than patient race.
4/21/2015 ... Childhood TBI is associated with an increased number of ALE and adult negative life outcomes.
Side of pupillary mydriasis predicts the cognitive prognosis in patients with severe traumatic brain injury
4/28/2015 ... Side of admission pupil abnormalities may be a useful variable to improve prognostic models for long-term cognitive performance in severe TBI patients.
4/30/2015 ... PTA duration proved to be a better predictor of driver assessment outcome than Glasgow Coma Scale score.
5/7/2015 ... Sleep disturbance, independent of psychological distress, is an important prognostic factor of functional and social outcomes after mild traumatic brain injury.
5/15/2015 ... This study empirically demonstrates that penetrating injury mechanism has important prognostic implications.
5/18/2015 ... Gender is implicated in the return to work process on many levels for men and women alike.
5/21/2015 ... Self-awareness variables at follow-up were predictive of community re-integration.
Findings offer further support for the cognitive reserve construct in explaining significant variance in TBI outcome, over and above the variance explained by injury severity.
6/9/2015 ... Premorbid lifestyle factors exerted a greater influence on mortality following TBI, compared with injury-related factors.
Survivors who received post-discharge rehabilitation had higher quality of life scores than those who did not.
6/25/2015 ... Marital status, injury severity and rehabilitation after injury were associated with community integration 2 years after TBI.
Job stability in skilled work and communication ability after moderate-severe traumatic brain injury
7/1/2015 ... This research associated communication functioning with work stability after TBI in skilled jobs.
7/2/2015 ... The prevalence of unemployment for patients completing inpatient rehabilitation for TBI was substantial (60.4%).
A systematic review of the effects of body temperature on outcome after adult traumatic brain injury
7/7/2015 ... Setting a goal of normothermia, avoiding fever, and aggressively treating fever may be most important after TBI.
7/10/2015 ... 35.5% (n=10,390) of patients with TBI were subsequently hospitalized during the 3 year follow-up period.
Early resuscitation with fresh frozen plasma for traumatic brain injury combined with hemorrhagic shock improves neurologic recovery
7/14/2015 ... Research data show that early treatment with FFP substantially attenuates the degree of neurologic impairment, improves the rate of recovery, and preserves the cognitive functions.
7/15/2015 ... Patients with mTBI and moderate-to-high resilience reported significantly fewer post-concussion symptoms, less fatigue, insomnia, traumatic stress, and depressive symptoms, and better quality of life, than the patients with low resilience.
7/23/2015 ... Males, people <35 years of age, and those who had experienced a TBI before their index injury were at highest risk of recurrent TBI.
7/24/2015 ... Delays in rehabilitation admission were negatively associated with outcome.
8/14/2014 ... Overall, as is the case in the general population, higher levels of education and pre-morbid IQ are both associated with better outcomes.
8/17/2015 ... Life expectancy of persons with TBI is lower than that of the general population and depends on age, sex, and severity of disability.
8/18/2015 ... Long-term survival prognosis in TBI is related to age, sex, and severity of disability.
Early endocrine alterations reflect prolonged stress and relate to 1-year functional outcome in patients with severe brain injury
8/21/2015 ... At 1 year after the injury, lower functioning level and lower capability of performing normal life activities were related to both the elevated stress hormones and the reduced gonadal and/or thyroid hormones measured at 3 months.
Predicting outcome after pediatric traumatic brain injury by early magnetic resonance imaging lesion location and volume
8/24/2015 ... Patients with lesions in all three zones had a significantly higher odds ratio for developing an unfavorable outcome.
8/31/2015 ... Threshold-guided CT scanning, adherence to Brain Trauma Foundation guidelines, and care for patients with TBI, including those with nonsurgical lesions, in specialized settings appear to be economically attractive strategies.
Acute alcohol intoxication in patients with mild traumatic brain injury: Characteristics, recovery and outcome
9/2/2015 ... At two weeks post-injury, intoxicated patients reported less complaints than the non-alcohol group and showed a better recovery at six months.
Prognostication of mortality and long term functional outcomes following traumatic brain injury: Can we do better?
9/4/2015 ... Overall, clinicians of varying backgrounds showed an accurate prediction of survival, but struggled in
prognosticating poor functional outcomes.
9/24/2015 ... We found strong evidence for a significant association between RTW and personal factors (education level, unemployment) after traumatic ABI, and activities of daily living (ADL) after non-traumatic ABI.
10/6/2015 ... Individuals with TBI who die several years after injury demonstrate functional trajectories that differ markedly from those of survivors.
Participants consistently reported that employers and workers' compensation representatives had an inadequate understanding of wrMTBI sequelae.
10/26/2015 ... The overall decline in trajectories of probability of employment between 5 and 10 years post-injury suggests that TBI may have unfavorable chronic effects
11/6/2015 ... Approximately 28% of patients with TBI were rehospitalized within 9
months of TBI rehabilitation discharge owing to various medical and surgical reasons.
Traumatic brain injury patient, injury, therapy, and ancillary treatments associated with outcomes at discharge and 9 months postdischarge
11/9/2015 ... At discharge, greater effort during therapy sessions, time spent in
more complex therapy activities, and use of specific medications were associated
with better outcomes for patients.
Group therapy use and its impact on the outcomes of inpatient rehabilitation after traumatic brain injury
11/10/2015 ... Variation in outcomes is not explained well by overall percentage of therapy time delivered in groups.
11/23/2015 ... Obesity had no adverse impact on motor functional outcomes of the traumatic brain injury patients who underwent inpatient rehabilitation.
12/9/2015 ... FIM levels improved during the period from rehabilitation unit discharge to 3 months follow-up; thereafter, there was a 'plateauing' of recovery.
12/9/2015 ... PHH status in men predicts poor outcome after severe TBI, and PHH can accurately be predicted at 12 to 16 weeks.
12/10/2015 ... Motor function recovery can occur beyond 6 years after severe traumatic brain injury, both in neural plasticity and clinical outcome.
12/29/2015 ... Results revealed significantly more attentional, emotional regulation, and psychological difficulties in the TBI group than controls.
1/7/2016 ... Positive BAC was significantly associated with lower mortality rates
in moderate to severe TBI.
Predictive value of hyperthermia and intracranial hypertension on neurological outcomes in patients with severe traumatic brain injury
1/14/2016 ... Hyperthermia combined with ICH were shown to be significant prognostic indicators of future poor neurologic outcomes in patients with severe traumatic brain injury.
1/25/2016 ... Serum GFAP levels on admission and during the first 5 days of injury were increased in patients with severe TBI and were predictive of neurological outcome at 6 months.
1/29/2016 ... HMGB1 can be massively induced by the systemic immune activation triggered by bone fracture, which in turn aggravates inflammation.
2/8/2016 ... Categorizing PTA to classify severity of injury may be reducing the precision with which clinicians can plan the treatment of patients after TBI.
3/15/2016 ... Cognition seemed to improve over time after sTBI and appeared to be rather stable from 3 months to 1 year.
3/17/2016 ... Multiple skull base fractures are associated with poor neurological outcome.
4/14/2016 ... Participants under the no-fault scheme experienced superior access to specialist rehabilitation services, greater surety of support and more choice over how rehabilitation and life-time care needs were met.
Predictors of global functioning and employment 10 years following traumatic brain injury compared with orthopaedic injury
4/15/2016 ... Demographic factors and injury severity contribute to long-term outcomes following TBI.
4/18/2016 ... Predictors of outcomes after inpatient rehabilitation differed by sex, providing evidence for a sex-specific approach in planning and resource allocation for inpatient rehabilitation services for patients with TBI.
4/26/2016 ... After adjusting for predictors of mortality, early administration of propranolol after TBI was associated with improved survival.
5/9/2016 ... Social participation and quality-of-life for persons instutionalized
several years after cerebral anoxia were improved by psychotherapeutic and therapeutic activities.
5/10/2016 ... Depression and the presence of a psychiatric history was associated with worse outcomes at three-month follow-up.
5/16/2016 ... In conclusion, TBI causes persisting intelligence impairments, where children may have better recovery from mild TBI and poorer recovery from severe TBI than adults.
5/17/2016 ... Psychological distress, global functioning postinjury, and the sick leave trajectory of the subjects were negative predictors for RTW.
5/23/2016 ... Although the prevalence of impairment may vary across cognitive domains, long-term follow-up documented deficits in all six domains.
6/2/2016 ... Predictors of outcomes after inpatient rehabilitation differed by sex, providing evidence for a sex-specific approach in planning and resource allocation for inpatient rehabilitation services for patients with TBI.
Relationship between quality-of-life after 1-year follow-up and severity of traumatic brain injury assessed by computerized tomography
7/5/2016 ... Patients with TBI had a high mortality rate 1 year after admission,
deterioration in QoL and significant impairment of functional status, although more than 40% were normal or self-sufficient.
7/6/2016 ... The presence of sleep features in the acute period after TBI indicates earlier participation in rehabilitative therapies and a better functional recovery.
7/14/2016 ... Hyperglycaemia after severe TBI is associated with poor outcome.
7/19/2016 ... Communication outcome and awareness of communication deficits play an important role in reintegration to the workplace following TBI.
7/21/2016 ... Mortality rate due to TBI in the alcohol-intake group appears to be lower compared to that in the no-alcohol-intake group after adjusting for main confounding variables.
Factors associated with long-term functional and psychological outcomes in persons with moderate to severe traumatic brain injury
7/26/2016 ... Cognitive and psychosocial problems are more commonly reported than physical disability in the longer-term.
Longitudinal outcome and recovery of social problems after pediatric traumatic brain injury (TBI): Contribution of brain insult and family environment.
8/5/2016 ... Poorer long-term social outcomes were associated with family dysfunction and poorer caregiver mental health at 24-months post injury, suggesting that efforts to optimize the child's environment and bolster family coping resources may enhance recovery of social problems following pediatric TBI.
8/16/2016 ...The significantly increased risks of multiple follow up visits and readmission among TBI patients who leave hospital AMA are related to a premorbid vulnerability and psychosocial issues.
Recovery of episodic memory subprocesses in mild and complicated mild traumatic brain injury at 1 and 12 months post injury
8/22/2016 ... While the NC-mTBI and HC groups' performances were comparable by 12 months, a primary, long-term deficit in encoding of auditory verbal information remained problematic in the comp-mTBI group.
8/23/2016 ... Age and LOS were considered independent predictors of QOL. Conclusion Age and LOS are independent predictors of QOL after moderate to severe TBI.
8/26/2016 ...This study indicates that return to productivity in a long-term perspective after a TBI is possible, in particular when the individual is young, has sustained a mild TBI and has a milder form of overall disability.
8/31/2016 ... Survivors of TBI have decreased life expectancy compared to the general population.
9/22/2016 ...In the courtroom, the defense attorney should educate the judge and/or the jury on the effects brain injuries have on the cognition, behavior, and emotions of an individual.
Prognostic models for predicting posttraumatic seizures during acute hospitalization, and at 1 and 2 years following traumatic brain injury
10/11/2016 ...The prognostic model for PTS during acute hospitalization did not discriminate well. Year 1 and year 2 models showed fair to good predictive validity for PTS.
The impact of preexisting illness and substance use on functional and neuropsychological outcomes following traumatic brain injury
10/18/2016 ... The findings showed that specific preexisting medical conditions are independently associated with lower functional and cognitive outcomes for patients with TBI.
Specific factors influence postconcussion symptom duration among youth referred to a sports concussion clinic
10/24/2016 ...Several factors help to predict protracted postconcussion symptom durations among youth referred to a sports concussion clinic.
10/27/2016 ... The lack of significant findings in women warrants further exploration of variables within the physical and social
environmental domains of the ICF.
The association between psychiatric comorbidities and outcomes for inpatients with traumatic brain injury
11/2/2016 ... Analysis revealed novel associations between coexisting psychiatric diagnoses and TBI outcomes, with some subgroups having decreased mortality and increased adverse discharge.
Experiences of patients with traumatic brain injury and their carers during transition from in-patient rehabilitation to the community
11/8/2016 ... Most patients and carers struggled to identify a cohesive plan that
supported their transition to living in the community.
11/30/2016 ... Memory disorder was the main predictive factor of impaired quality of life of traumatic brain injury patients.
Mindful creativity matters: trajectories of reported functioning after severe traumatic brain injury as a function of mindful creativity in patients' relatives
12/6/2016 ... Relatives' mindful creativity was significantly associated with patients' functioning after severe TBI. Implications for treatment and future research are discussed.
12/15/2016 ... This study highlights the benefits of religious attendance on psychosocial outcomes post-TBI.
12/29/2016 ... Alcohol may not significantly alter long-term outcome from mild to moderate TBI.
12/30/2016 ... There exists an association between obesity and increased time to return to neurocognitive and symptom baseline after SRC in athletes, specifically reaction time, symptom scores, and overall recovery.
The relationship between family expressed emotion, perceived criticism and criticism sensitivity and psychiatric outcomes following traumatic brain injury
1/10/2017 ... Findings suggest that sensitivity to interpersonal criticism may have a role in the development and course of psychiatric disorders following TBI.
1/13/2017 ... PCS may be permanent if recovery has not occurred by 3 years.
1/16/2017 ... There was a substantial deficit accrued as a result of the management of patients with TBI.
5/16/11 ... Stronger and tougher body armor to shield the chest, abdomen and back may be just what soldiers fighting in the Afghanistan and Iraq wars need to better protect their brains from mild injuries tied to so-called "shell shock," results of a Johns Hopkins study in mice suggest.
12/19/11 ... New research shows that including probiotics with nutrients reduced the amount of time patients spent in intensive care.
In general, post-TBI drivers have a higher occurrence of multiple crashes and this should be further explored to guide driver rehabilitation, evaluation, and training.
5/28/2014 ... Car safety seats prevent injuries. However, TBI is similar among properly restrained and improperly/unrestrained infants involved in higher speed MVCs who present to a trauma center.
8/19/2015 ... Among young adults men and unemployed men have a higher statistical probability to have consumed alcohol prior to suffering mild traumatic brain injury.
9/2/2015 ... A multivariable logistic regression model showed that helmeted bicyclists were 72% less likely to sustain TBI compared with un-helmeted bicyclists.
4/29/2016 ... Cyclists without helmets were younger, less educated, single and unemployed. They had more severe TBIs on imaging, longer LOS in ICU and more neurosurgical interventions.
6/27/2016 ... Medical charges and rates of head, facial, and brain injuries among motorcyclists were lower in universal law states. Helmets were effective in reducing injury in both helmet law settings.
6/13/11 ... Baseline concussion tests given to hundreds of thousands of athletes might, paradoxically, increase risks in some cases, according to a Loyola University Health System researcher.
7/18/11 ... New Findings Provide Important Data for Refining Diagnosis.
09/06/11 ... A sideline visual test effectively detected concussions in collegiate athletes, according to a team of researchers from the Perelman School of Medicine at the University of Pennsylvania. Concussed athletes scored an average of 5.9 seconds slower (worse) than the best baseline scores in healthy controls on the timed test, in which athletes read a series of numbers on cards and are scored on time and accuracy.
12/21/11 ... Research finds impaired cerebrovascular reactivity among concussed athletes.
12/22/11 ... The brain scans of high school football and hockey players showed subtle injury -- even if they did not suffer a concussion -- after taking routine hits to the head during the normal course of play.
Study Shows Second Impact Syndrome Occurrences Increasing, New York Passes Concussion Management and Awareness Act
12/26/11 ... More and more sports athletes are suffering from Second Impact Syndrome (SIS). A study published in the Journal of Pediatrics draws attention to the potential dangers of interscholastic sports.
1/24/12 ... Second impact syndrome is believed to be the catastrophic consequence of repeated head injury in sport.
5/13/2013 ... Even in the absence of concussion, football players may experience repeated BBBD and serum surges of the potential auto-antigen S100B. The correlation of serum S100B, auto-antibodies and DTI changes support a link between repeated BBBD and future risk for cognitive changes.
9/3/2013 ... Heading is associated with abnormal white matter microstructure and with poorer neurocognitive performance.
8/20/2015 ... Evidence of VOD was detected in a significant proportion of children and adolescents with acute SRC and PCS.
1/12/2016 ... Significant main effects between participants with concussion history and healthy controls without concussion history were observed in timing and accuracy measures.
6/29/2016 ... The findings suggest no clinically significant age differences exist in recovery after sport-related concussion.
7/8/2016 ... Female athletes sustained a higher rate of concussion and, in all sports except lacrosse, had greater time loss from concussion than male athletes.
8/10/2016 ... There appears to be a growing body of evidence supporting the presence of long-term psychiatric and psychological sequelae following sport concussion in adults.
10/19/2016 ...This study provides the first evidence of the long-term effects of concussion on gray matter volume, blood flow, and white matter microstructure within a single athlete cohort.
12/28/2016 ... There was a positive association between concussion history and lower extremity injuries.
6/27/11 ... The construction industry had the highest number of TBIs and the agriculture, forestry, and fishing industry had the highest rates.
1/12/12 ... Epidemiology of traumatic brain injury (TBI) is changing in several western countries, with an increasing proportion of elderly TBI patients admitted to ICU.
2/16/12 ... Though researchers are becoming increasingly aware of the long-term effects of head injury, few studies have looked at the prevalence of traumatic brain injury (TBI) in all age groups, including males and females, taking into account both mild and serious events.
8/16/2012 ... Preventing probable and possible events might facilitate substantial reductions in TBI-associated medical care costs.
10/19/2012 ... Facial fractures are often associated with brain injury. A high level of suspicion is warranted for minor traumatic brain injuries.
10/31/2012 ... Motor vehicle accidents and firearms were identified as leading causes of injury and mortality for adolescent TBI and represent potential targets for intervention.
Limited predictive power of hospitalization variables for long-term cognitive prognosis in adult patients with severe traumatic brain injury
12/18/2012 ... After correction for education and age distribution, the variables that are commonly associated with mortality or Glasgow Outcome Scale including admission pupils' examination, Marshal CT Classification, GCS, and serum glucose showed a limited predictive power for long-term cognitive prognosis.
1/14/2013 ... The adverse behavioral, cognitive and psychiatric effects
associated with TBI coupled with the high prevalence of TBI identified in this
study indicate that TBI is a considerable public and personal-health problem.
6/24/2013 ... Of 581 TBI cases reviewed, 56 (10%) cases were reported as ccupational by either the patient or the informant accompanying the patient.
6/28/2013 ... Duration of post-traumatic amnesia (PTA) was a strong predictor of all costs and stronger than Glasgow Coma Score.
8/12/2013 ... There is significant geographic variation for both mortality and hospital costs.
8/7/2014 ... Homeless individuals with a lifetime history of TBI are more likely to be ED users, arrested or incarcerated, and victims of physical assault over a 1-year follow-up period.
10/31/2014 ... TBI epidemiology in Western countries has changed across a number of factors.
3/18/2015 ... TBI is common in the homeless relative to the general population and is a risk factor for late mortality in the homeless population.
4/2/2015 ... PTA duration was the strongest predictor across all cost categories.
4/8/2015 ... This study underscores the possible role of TBI history as a risk factor for onset of cocaine use.
5/12/2015 ... This is the first population-based study to demonstrate a relationship between a history of TBI and higher rates of serious driver aggression and collision involvement.
1/18/2016 ... This study highlights an upward trend in rates of ED visits for mild TBI among older adults.
1/18/2016 ... This study highlights an upward trend in rates of ED visits for mild TBI among older adults.
A profile of patients with traumatic brain injury within home care, long-term care, complex continuing care, and institutional mental health settings in a publicly insured population
3/14/2016 ... Patients with TBI were significantly different on almost all items. They were among the youngest in care settings, and psychotropic drug use by this population was among the highest in at least 2 settings.
5/4/2016 ... ED visits for TBI are involving older populations with increasingly
6/9/2016 ... Rehospitalization after TBI is common.
7/11/2016 ... Indices of health, mood, and functional status predict incident TBI with LOC in older adults.
The prevalence of traumatic brain injury among people with co-occurring mental health and substance use disorders
10/6/2016 ... TBI is common among people with co-occurring mental health and substance use disorders.
11/1/2016 ... The incidence of concussion diagnosed in the general US population is
increasing, driven largely by a substantial rise in the adolescent age group.
11/18/2016 ... The studies identified in this review clearly emphasize the need to account for TBI in managing care in offender populations.
2/6/12 ... In this study as the severity of bodily injuries increased, symptom burden decreased.
2/7/12 ... It is important for clinicians to recognize major depression following traumatic brain injury (TBI) because of its association with poor global and psychosocial outcome, postconcussive symptoms and cognitive deficits.
2/10/12 ... Study examines the prevalence and characteristics of acute posttraumatic headache (APTH) attributed to mild head injury within a prospective, observational study design.
2/23/12 ... Noise sensitivity is an important and under-researched symptom that can result from traumatic brain injury (TBI).
3/2/2012 ... People who experience a traumatic brain injury show a marked decline in the ability to make appropriate financial decisions in the immediate aftermath and a continued impairment on complex financial skills six months later.
3/12/2012 ... TBI and psychiatric illness were each associated with significant increases in health care costs; those with the combination of moderate-to-severe TBI and psychiatric illness had much higher costs than any other group.
3/13/2012 ... The study provides good support for the proposed cognitive behavioural model. Patients' perceptions of their head injury and their behavioural responses play important roles in the development of PCS, indicating that cognitive and behavioural factors may be potential targets for early preventive interventions.
4/5/2012 ... Given the evident influence of both premorbid and concurrent psychiatric problems, especially anxiety, on postinjury symptoms, managing the anxiety response in vulnerable individuals with mTBI may be important to minimize ongoing sequelae.
4/6/2012 ... Sleep disruption is common following traumatic brain injuries and the majority developed a chronic sleep disorder.
4/17/2012 ... There is some evidence that reduced evening melatonin production due to traumatic brain damage may cause disruption of circadian regulation of sleep and wakefulness.
Prevalence of traumatic brain injury in intimate partner violence offenders compared to the general population: A meta-analysis
4/23/2012 ... TBI may be a risk factor for interpersonal violence, although comparatively few source studies, lack of standardized information about TBI severity, and the inability to investigate potential confounding variables necessarily limit this conclusion.
Changes in emotional empathy, affective responsivity, and behavior following severe traumatic brain injury
4/27/2012 ... The results represent the first to suggest that level of emotional empathy post traumatic brain injury may be associated with behavioral manifestations of disorders of drive and control.
The relations among cognitive impairment, coping style, and emotional adjustment following traumatic brain injury
5/8/2012 ... Greater impairments in cognition directly predicted higher levels of anxiety and depression following TBI.
5/21/2012 ... We conclude that headaches occurring after various types of head injury, including explosions, can be assigned primary and secondary headache diagnoses using standard classifications not necessarily available to larger survey-based studies.
5/29/2012 ... A number of factors appear to combine to result in feelings of strain, but the GOS could be used as a crude screening tool.
Treatment consent capacity in patients with traumatic brain injury across a range of injury severity
5/31/2012 ... One month following injury, MDC is largely intact in patients with mTBI, but is impaired in patients with cmTBI and msevTBI.
6/12/2012 ... Results provide empirical support that PTC is associated with poorer cooperation and empirical justification for interventions to manage confusion during early recovery from traumatic brain injury.
6/15/2012 ... Fatigue appeared to be a more prominent symptom than sleepiness when assessed between 1 and 11 years after TBI.
Depression, anxiety and quality-of-life among relatives of patients with severe brain injury: The acute phase
6/20/2012 ... The majority of the relatives had severely impaired quality-f-life and symptoms of anxiety and depression during the patient's NICU stay.
6/21/2012 ... These findings suggest a possible degenerative effect of concussions on olfactory function.
Fatigue and sleep disturbance following traumatic brain injury-their nature, causes, and potential treatments
6/26/2012 ... These findings suggest potential treatments including cognitive behavior therapy supporting lifestyle modifications, pharmacologic treatments with modafinil and melatonin, and light therapy to enhance alertness, vigilance, and mood.
Irritability following traumatic brain injury: Divergent manifestations of annoyance and verbal aggression
6/27/2012 ... Results showed that annoyance might be the main characteristic of irritability in TBI patients and patients themselves might be unaware of their verbal aggression post-injury.
Determinants of subjective memory complaints in community-dwelling adults with mild-to-moderate traumatic brain injury
6/28/2012 ... Self-reported chronic situational stress is positively associated with self-reported memory complaints, as well as somatic and communication difficulties.
Are there gender differences in cognitive function, chronic stress, and neurobehavioral symptoms after mild-to-moderate traumatic brain injury?
7/3/2012 ... Overall, this study only found gender differences on verbal memory composite scores, whereas the remaining cognitive tasks, neurobehavioral symptoms, and chronic stress did not indicate gender differences.
7/6/2012 ... Findings suggest that levels of EE within the family are associated with psychological adjustment following TBI.
Prevalence of sleep disturbances, disorders, and problems following traumatic brain injury: A meta-analysis
7/17/2012 ... Sleep disturbances are very common after TBI and have the potential
to seriously undermine patient rehabilitation, recovery, and outcomes; making it important to routinely screen for such problems in order to assess both treatment needs and their potential impact on recovery and outcome.
7/19/2012 ... A complete hormonal investigation should be performed after one year of the trauma. Isolated growth hormone deficiency is the most common deficiency after traumatic brain injury.
8/9/2012 ... Findings suggest that interventions targeting strengthening the injured persons' sense of belonging and lowering interpersonal conflict may benefit those living with TBI.
Association between posttraumatic stress, depression, and functional impairments in adolescents 24 months after traumatic brain injury
8/24/2012 ... Results indicated that patients who sustained a mild TBI without intracranial hemorrhage reported significantly worse PTSD (Hedges g = 0.49, p = .01; Model R(2) = .38) symptoms across time as compared to
the arm injured control group. Greater levels of PTSD symptoms were associated with poorer school (η(2) = .07, p = .03; Model R(2) = .36) and physical (η(2) =
.11, p = .01; Model R(2) = .23) functioning, whereas greater depressive symptoms were associated with poorer school (η(2) = .06, p = .05; Model R(2) = .39) functioning.
Depression, anxiety, and stress as predictors of postconcussion-like symptoms in a non-clinical sample
8/27/2012 ... Results suggest that stress may be a more important predictor of postconcussion-like symptoms than previously identified.
Partners of patients with acute brain injury: Anxiety and depression in the acute and sub-acute phase
9/6/2012 ... Partners of patients low in functional capacity exhibited a higher level of depression. Women were more distressed than men. Additional burden due to psychosocial background stress, acute care of the patient, and daily visits were associated with higher
9/10/2012 ... A range of visual and visual-motor impairments are seen across the severity of traumatic brain injury.
Ageing and traumatic brain injury: Age, decline in function and level of assistance over the first 10 years post-injury
9/11/2012 ... For those individuals that survive to 10 years post-TBI, age is a major factor in requiring assistance of another person for supervision as well as assistance in basic self-care, continence and mobility.
9/19/2012 ... Migraine/probable migraine described the majority of headache after TBI across one year post-injury.
9/24/2012 ... Fatigue appeared to be a more prominent symptom than sleepiness when assessed between 1 and 11 years after TBI. Participants with TBI used
compensatory strategies such as increasing time spent in bed and daytime napping in this sample.
Effective factors on linguistic disorder during acute phase following traumatic brain injury in adults
9/25/2012 ... The dissociation risk of cortical and subcortical pathways related to cognitive-linguistic processing due to intracranial lesions can augment possibility of lexical- semantic processing deficit in acute phase which probably contributes to later cognitive-communication disorder.
9/26/2012 ... Noise sensitivity is an important and under-researched symptom that can result from traumatic brain injury (TBI). Interpretative phenomenological analysis (IPA) was used to analyse the experiences of noise sensitivity of six individuals with TBI.
10/4/2012 ... This study showed that behavioural performance and cerebral functioning are affected by pain after a MTBI.
10/16/2012 ... Despite several interventions used to prevent post traumatic epilepsy, the only proven "intervention" to date is to prevent TBI from occurring.
10/24/2012 ... MTBI-induced differences in working memory functional activity were observed even though differences in
behavioral performance between MTBI patients and controls were absent, which suggests that this approach may increase sensitivity to MTBI compared with neuropsychological evaluation alone.
10/26/2012 ... Traumatic brain injury is a frequent condition worldwide, and sleep-wake disturbances often complicate the course after the injuring event.
Impaired response inhibition in veterans with post-traumatic stress disorder and mild traumatic brain injury
11/6/2012 ... PTSD patients showed a significant deficit in response inhibition,
committing more errors on NoGo trials than controls.
11/8/2012 ... left-dominant brain
immune network may mediate vulnerability to infection during rehabilitation of stroke and TBI patients.
11/9/2012 ... The risk of epilepsy after TBI varied by patient gender, age, latent interval and complexity of TBI.
11/20/2012 ... The presence of alexithymia in persons with TBI is an important factor affecting relationship quality and satisfaction.
12/13/2012 ... These preliminary findings suggest that patients with TBI are impaired at expressing sad expressions either spontaneously or deliberately.
12/24/2012 ... Research indicates there are extensive changes to identity after a brain injury and this impacts returning to previous occupations.
1/4/2013 ... This study showed that behavioral performance and cerebral functioning are affected by pain after a MTBI.
1/11/2013 ... TBI patients were less accurate than the controls on the time discrimination task and showed greater time-order error effects.
Autobiographical memory and episodic future thinking after moderate to severe traumatic brain injury
1/15/2013 ... Results revealed that TBI patients recalled/imagined proportionally fewer episodic event-specific details for both past and future events compared to healthy controls (η(2) (p) = 0.78).
Post-concussive complaints, anxiety and depression related to vocational outcome in minor to severe traumatic brain injury
1/23/2013 ... Anxiety and depression are
related to vocational outcome after TBI, with a different profile in the minor
TBI category, partly due to sex differences.
1/29/2013 ... Convergence insufficiency without simultaneous visual or vestibular
dysfunctions was observed in about 9% of the visually symptomatic TBI civilian
population studied. A thorough visual and vestibular examination is recommended
for all TBI patients.
1/30/2013 ... These results showed abnormal
DMN connectivity patterns in patients with MTBI, which may provide insight into
how neuronal communication and information integration are disrupted among DMN
key structures after mild head injury.
Reduced contribution of executive functions in impaired working memory performance in mild traumatic brain injury patients
2/25/2013 ... We suggest that MTBI may lead to WM deficits as the contribution of executive processes to support the WM is diminished following MTBI.
Emotional regulation impairments following severe traumatic brain injury: An investigation of the body and facial feedback effects
3/7/2013 ... TBI appears to impair the ability to recognize both the physical configuration of a negative emotion and its associated subjective feeling.
3/12/2013 ... The current study provides evidence showing that pre- and postinjury alcohol use is negatively associated with different aspects of cognitive functioning following TBI.
Anxiety sensitivity and alexithymia as mediators of postconcussion syndrome following mild traumatic brain injury
3/15/2013 ... A combination of low mood and high AS may act as a psychological
diathesis for the development of persisting PC symptoms.
3/18/2013 ... In summary, the study found a
higher prevalence of dry eye disease in subjects with TBI, both subjectively and objectively.
3/22/2013 ... The finding that half the individuals recovering from MTBI do not
intend to moderate their driving exposure post-injury is cause for concern, as another study has shown that driving performance is compromised in this group immediately after injury.
Depression and anxiety in parent versus spouse caregivers of adult patients with traumatic brain injury
3/29/2013 ... Overall, high levels of caregiver distress were exposed, regardless of caregiver type (parent versus
Unique contribution of fatigue to disability in community-dwelling adults with traumatic brain injury
4/1/2013 ... Fatigue contributes uniquely to disability status among community-dwelling adults with chronic TBI, independent of injury severity, executive functions, and depression.
4/4/2013 ... Surgical resection of heterotopic ossification of the shoulder is an effective procedure to increase joint mobility and improve function.
4/8/2013 ... These results suggest that the reduction in cognitive performance is not due to greater symptom report itself, but is associated to some extent with the initial injury.
4/9/2013 ... Results suggest that people who have a tendency to avoid thinking about emotions (externally-oriented thinking) are more likely to have problems recognizing others' emotions and assuming others' points of view.
4/17/2013 ... Clinically, patients with dementia associated with TBI were more likely to have symptoms of depression, agitation, irritability, and motor dysfunction than patients with probable AD.
4/18/2013 ... The results of this study suggest that temporal discounting may be a useful neuropsychological paradigm to assess decision making linked to monetary reward following TBI.
4/22/2013 ... Individuals aged 65 or older who reported a history of TBI with LOC
at any time in their lives were at elevated risk of subsequent re-injury.
Pituitary function and functional outcome in adults after severe traumatic brain injury: the long-term perspective
4/24/2013 ... This study-which is unique in the homogeneity of the patients, the long follow-up time, and the use of injury severity as an outcome predictor-did not confirm results from previous studies linking PTHP to a worse outcome.
Psychotic symptoms as manifestations of the posttraumatic confusional state: Prevalence, risk factors, and association with outcome
4/30/2013 ... These findings suggest that improved sleep in early TBI recovery may decrease the occurrence of psychotic-type symptoms.
Preinjury coping, emotional functioning, and quality of life following uncomplicated and complicated mild traumatic brain injury
5/1/2013 ... Cluster analysis holds practical value in illustrating the pattern of coping strategies used by
person with uncomplicated and complicated mTBI.
Low self-awareness of individuals with severe traumatic brain injury can lead to reduced ability to take another person's perspective
5/3/2013 ... The analysis suggests a causal relationship between low self-awareness and perspective-taking difficulties in this population of patients.
5/22/2013 ... Many people with TBI may
actually be capable of running, despite the presence of significant biomechanical
abnormalities during gait.
Prevalence of low bone mineral density in inpatients with traumatic brain injury receiving neurobehavioural rehabilitation
5/23/2013 ... Some participants had reduced BMD, putting them at risk of fracture or of developing such risk in the future.
5/29/2013 ... Although, in the control situation, patients' results were equivalent to controls', they displayed specific disorders in more complex situations where the attentional load increased.
5/30/2013 ... In patients with mild and moderate TBI, ACTH and GH deficiencies may improve over time in a considerable number of patients but, although rarely, may also worsen over the 5 year period.
6/4/2013 ... Participants with prior MTBIs did not report more postconcussion symptoms than those with no history of prior MTBI.
6/5/2013 ... The findings support the notion that the TBI-A group demonstrated
considerably weaker performance on executive tasks than did the nonanosmic TBIs.
6/19/2013 ... post-MTBI, cognitive, high-level language and isolated general language performance (e.g. naming) is significantly reduced in MTBI patients, compared to normal controls.
6/25/2013 ... Individuals with HA at three months after moderate-severe TBI do not improve over the ensuing nine months with respect to HA density or ADL disruptions.
6/26/2013 ... Findings provide empirical support for the notion of a multi-factorial CR and suggest a coherent framework for further investigation.
Do survivors of acute neurologic injury remember their stay in the neuroscience intensive care unit?
7/10/2013 ... Patients requiring prolonged neuroscience ICU admission do not appear to be traumatized by their ICU stay.
7/12/2013 ... The history of alcohol and drugs abuse is common in patients with TBI and it is a risk factor for development of behavioral disorders.
Emotional regulation impairments following severe traumatic brain injury: an investigation of the body and facial feedback effects.
7/17/2013 ... TBI appears to impair the ability to recognize both the physical configuration of a negative emotion and its associated subjective feeling.
7/18/2013 ... Men exhibited higher risks of post-TBI epilepsy. Patients who had mixed types of cerebral haemorrhage were at the highest risk of epilepsy compared with the non-TBI cohort (HR 7.83, 95% CI 4.69 to 13.0). The risk of post-TBI epilepsy was highest within the first year after TBI (HR 38.2, 95% CI 21.7 to 67.0).
7/25/2013 ... The purpose of this study was to investigate, in a sample of people with acquired brain injury (ABI), the contribution of illness perceptions, distress, disability, and coping strategies and health to post-traumatic growth.
7/29/2013 ... Suicide risk is higher among military personnel with more lifetime TBIs, even after controlling for clinical symptom severity.
Prevalence, clinical features, and correlates of inappropriate sexual behavior after traumatic brain injury
7/30/2013 ... ISBs pose a complex clinical challenge among a minority of individuals with severe TBI.
7/31/2013 ... Therapeutic interventions for sexuality need to focus on depression where indicated and self-esteem and address specific barriers to social participation and opportunities for sexual contact in individuals who are less independent in ADL.
8/1/2013 ... We showed that long-lasting TBI patients who develop hypopituitarism frequently present metabolic alterations, in particular altered glucose levels, insulin resistance and hypertriglyceridemia.
8/6/2013 ... Sexual function and satisfaction appears to be stable in those with moderate to severe TBI from 6 to 12 months after injury, with the exception of minimal improvement in arousal.
8/22/2013 ... Over a median period of 38 months, 42% of TBI patients gained and 28% lost weight.
8/27/2013 ... Results are consistent with TBI producing impairments in emotional empathy and responsivity.
8/29/2013 ... The current findings indicated that
deficits in social skills are long lasting and raises the issue of whether intervention to improve sensitivity to genuine emotion can influence more complex social skills and improve quality of social interactions for individuals following TBI.
9/6/2013 ... As lower scores of FAC is an independent risk factor for HO formation and is related to the severity and consequences of injury, ambulation and regular/cautious mobilization of the joints are of paramount importance in the early period of the rehabilitation in TBI patients.
The influence of chronic cigarette smoking on neurocognitive recovery after mild traumatic brain injury
9/12/2013 ... Greater lifetime duration of smoking and pack-years were related to significantly less improvement on multiple domains.
9/13/2013 ... Growing evidence indicates that multiple types of brain injury, including traumatic brain injury, are dynamic conditions that continue to change years after onset.
The relationship between facial affect recognition and cognitive functioning after traumatic brain injury
9/18/2013 ... Impairment in several cognitive processes may contribute to facial affect recognition deficits in TBI, in particular non-verbal memory, working memory and speed of processing.
Pain and mild traumatic brain injury: The implications of pain severity on emotional and cognitive functioning
9/19/2013 ... High chronic pain exacerbates the emotional aspect of PCD and, therefore, should be given special observance in treatment settings.
10/2/2013 ... Fatigue plays a different role in the subjective experience of sexual activity for men and women with TBI than for those without brain injuries.
10/7/2013 ... Post-traumatic pleiosomnia may be even more frequent than reported previously, because affected patients often underestimate their actual sleep need.
10/14/2013 ... Correlation analyses revealed a significant positive correlation between urgency (the tendency to act rashly when distressed) and prepotent response inhibition in patients with TBI.
10/17/2013 ... Children with a history of a previous concussion, particularly recent or multiple concussions, are at increased risk for prolonged symptoms after concussion.
10/23/2013 ... Traumatic brain injury causes a delayed but significant decrease in intestinal contractile activity in the ileum leading to delayed transit.
Association of daytime somnolence with executive functioning in the first 6 months after adolescent traumatic brain injury
10/28/2013 ... The parent report of daytime somnolence correlated with TBI severity and predicted executive functioning difficulties of the teens in everyday circumstances.
11/5/2013 ... People with TBI who have impaired affect recognition may have problems identifying both positive (happy) and negative expressions. Furthermore, people with TBI may perceive affect when there is none.
11/21/2013 ... Pituitary dysfunction is prevalent following TBI. Pituitary dysfunction seems to influence functional outcomes in some patients recovering from brain injury.
12/10/2013 ... The ability to read pleasant and unpleasant emotions in other people's faces is a complex process involving not only a common network that includes bilateral fronto-temporo-limbic lobes, but also other regions depending on emotional valence.
12/18/2013 ... Patients with TBI II° and III° exhibit smell loss in 57 %. Chances for olfactory recovery were highest within the first 6 months after the trauma.
Evaluating the impact of treatment for sleep/wake disorders on recovery of cognition and communication in adults with chronic TBI
12/19/2013 ... These results add to a small but growing body of evidence that sleep/wake disorders associated with TBI exacerbate trauma-related cognitive, communication and mood impairments.
12/31/2013 ... The loss of work capacity and high levels of disability for the CPTH patients suggests directions for further research into what important factors are embedded in the patients' PTSD symptoms and might explain their prolonged illness.
Depressive symptoms and psychological distress during the first five years after traumatic brain injury
1/7/2014 ... Psychosocial stressors and employment status contributed to depressive symptoms and psychological distress, whereas injury severity did not have any predictive value.
1/20/2014 ... Individuals with HA at three months after moderate-severe TBI do not improve over the ensuing nine months with respect to HA density or ADL disruptions.
1/21/2014 ... The presence of alexithymia in persons with TBI is an important factor affecting relationship quality and satisfaction.
2/7/2014 ... Persons with brain injury self-reported negative psychological effects of ostracism including a lower sense of belonging, self-esteem and meaningful existence.
2/27/2014 ... Data support and contribute to a growing body of evidence which indicates that TBI patients with insomnia are prone to suffer from concomitant headache and/or dizziness, report more symptoms of anxiety and depression and severe TBI patients are likely to experience hypersomnia.
2/28/2014 ... In this case of post-traumatic anosmia, the ability to perceive and recognize odours does not seem to be compromised in the same measure.
3/11/2014 ... At 3 months after injury, 33% of the mTBI subjects were functionally impaired; 22.4% of the mTBI subjects available for follow-up were still below full functional status at 1 year after injury.
3/24/2014 ... The TBI patients had difficulty processing tonality, therefore, it is reasonable to suggest that clinicians, friends, and family members should emphasize the explicit verbal content of spoken language when speaking to a person with TBI.
Head injury and loss of consciousness raise the likelihood of developing and maintaining PTSD symptoms
3/26/2014 ... Survivors with loss of consciousness and head injury had higher prevalence of PTSD and higher levels of PTSD symptoms, suggesting that patients with head injury and loss of consciousness reported in the emergency department are at higher risk for PTSD.
Clinical outcomes, predictors, and prevalence of anterior pituitary disorders following traumatic brain injury
4/8/2014 ... Approximately one third of traumatic brain injury patients have persistent anterior pituitary disorder.
4/10/2014 ... Findings indicate that psychiatric symptoms are common in the first 6 months post TBI and frequently extend beyond the depression and anxiety symptoms that may be most commonly screened.
4/16/2014 ... Survivors of ABI are vulnerable to stigma and discrimination.
4/24/2014 ... Patients with acute moderate/severe TBI had an altered rest-activity cycle, probably reflecting severe fragmentation of sleep and wake episodes, which globally improved over time.
4/28/2014 ... Processing speed emerged as the strongest model associated with anxiety disorder.
5/5/2014 ... Post-traumatic pleiosomnia may be even more frequent than reported previously, because affected patients often underestimate their actual sleep need.
5/9/2014 ... Time post TBI, cognitive outcome and initial discharge destination are the strongest predictors of mood up to 3 years after TBI.
5/12/2014 ... The consequences of TBI may be greater in individuals with ESD owing to the potential for a more severe or repetitive TBI.
5/21/2014 ... Self-concept may be lowered following TBI and is associated with negative emotional consequences.
6/1/2014 ... Multivariable logistic regression analysis revealed that increased age, low RLA score, tracheostomy tube placement, and aphonia observed on the initial swallowing evaluation significantly increased the odds of being discharged from the acute-care hospital with a feeding tube.
6/5/2014 ... Parents with TBI who have been identified as high risk for engaging in child abuse have increased risk for mental health problems and criminal offending.
6/10/2014 ... These results suggest that concussion history has a negative effect on visual processing in young adults.
6/16/2014 ... Sleep disturbances experienced soon after trauma predicted neuropsychiatric symptoms 1 year after injury.
6/17/2014 ... It was found that HRV was considerably reduced in an heterogenic ABI patient group admitted for neurorehabilitation.
6/19/2014 ... TBI survivors and persons with LD do not differ markedly in terms of expressive writing skill.
Early trajectory of psychiatric symptoms after traumatic brain injury: relationship to patient and injury characteristics
6/23/2014 ... Findings indicate that psychiatric symptoms are common in the first 6 months post-TBI and frequently extend beyond the depression and anxiety symptoms that may be most commonly screened.
7/7/2014 ... Cardiac dysfunction in the setting of isolated traumatic brain injury occurs and is associated with increased in-hospital mortality.
7/11/2014 ... Results suggest that people who have a tendency to avoid thinking about emotions (externally-oriented thinking) are more likely to have problems recognizing others' emotions and assuming others' points of view.
7/30/2014 ... Radiation exposure from the use of CT in the evaluation and management of severe traumatic brain injury causes negligible increases in lifetime attributable risk of cancer and cancer-related mortality.
8/1/2014 ... Microstructural abnormality in the fasciculus, likely from the traffic accident, caused reduced afferent feedback to the brain, resulting in less efficient decision-making.
8/22/2014 ... Individuals after TBI use two main sets of coping strategies that are differentially associated with HRQoL (and clinical variables). One is adaptive and the other maladaptive.
Prevalence, comorbidities, and correlates of challenging behavior among community-dwelling adults with severe traumatic brain injury
8/26/2014 ... Challenging behaviors are widespread among community-dwelling adults with severe traumatic brain injury.
8/27/2014 ... Participants who were older and female tended to avoid a greater number of challenging everyday driving scenarios.
Suicidality, bullying and other conduct and mental health correlates of traumatic brain injury in adolescents
9/5/2014 ... Significant associations between TBI and adverse internalizing and externalizing behaviours were found.
9/8/2014 ... Fatigue after TBI is a cause, not a consequence, of anxiety, depression, and daytime sleepiness.
9/10/2014 ... Lower quality sexual functioning and satisfaction was present in persons with TBI and concomitant unemployment or lower annual income.
9/11/2014 ... The degree of facial affect impairment was significantly greater than vocal affect impairment in this sample of people with moderate-to-severe TBI.
9/15/2014 ... Insomnia is a prevalent condition after TBI requiring more clinical and scientific attention as it may have important repercussions on rehabilitation.
Twenty-five percent of the sample reported SI during 1 or more assessment points.
9/29/2014 ... We found problems with inhibiting the self-perspective accords with descriptive accounts of the egocentric nature of some communication patterns following TBI.
Predicting posttraumatic stress symptoms following traumatic brain injury: The role of posttraumatic amnesia
10/1/2014 ... A brief duration of PTA is a significant risk factor for the development of posttraumatic stress disorder symptoms.
The impact of alexithymia on burnout amongst relatives of people who suffer from traumatic brain injury
10/13/2014 ... Relatives who present with alexithymia need to be identified at an early stage to minimize risks of burnout leading to adverse effects on patient-caregiver relationships.
10/17/2014 ... Vital signs were identified as potential indicators of pain in TBI patients.
10/28/2014 ... Depression is very common after TBI and has the potential to impact on recovery and quality of life.
11/3/2014 ... Four years after a severe traumatic brain injury, 44% of ICs experienced a heavy multidimensional burden.
11/6/2014 ... Advanced imaging methods detect a spectrum of injury suggesting involvement of the neurovascular unit in the presence of persistent symptoms.
11/10/2014 ... A sizeable proportion of individual TBI patients in each group continued to demonstrate capacity compromise at six-months post-injury.
11/13/2014 ... Poor sleep efficiency is a common symptom in the first year among patients with first-ever TBI.
11/14/2014 ... Lack of a social network, feeling loneliness, and patient's functional status are predictors of caregiver burden.
12/9/2014 ... Fatigue plays a different role in the subjective experience of sexual activity for men and women with TBI than for those without brain injuries.
Impact of depression and PTSD on functional outcome and quality of life of patients with mild traumatic brain injury
12/15/2014 ... Depression and/or PTSD are relatively common in our sample of TBI patients and that it is associated with a considerable decrease in functional outcome.
12/17/2014 ... These data corroborate recent findings in an alternate neurological population and suggest that WM is an underlying mechanism of CR.
12/31/2014 ... Results suggest that the relationship between pTBI-related aggression and the dopaminergic system is modulated by lesion location.
1/6/2015 ... We found no evidence for an association between structural brain injury and malignant astrocytic tumors within the first 5 years of follow-up.
1/12/2015 ... Our findings indicate that individuals with TBI have an overall deficit in facial emotion recognition, and that both people with TBI and control participants found some emotions more difficult than others.
1/22/2015 ... Injury severity, education, and time since injury should be assessed, and at-risk patients should be informed of the consequences of alcohol use among those with TBI.
1/28/2015 ... Victims of severe TBI and/or patients who have undergone neurosurgical intervention for head injury are the most prone to post-traumatic hypopituitarism.
Associations between history of traumatic brain injury and current cigarette smoking, cannabis use, nonmedical opioid use, and elevated psychological distress
2/5/2015 ... There was co-occurrence of a history of TBI with current elevated psychological distress and substance use.
Influence of self-efficacy and coping on quality of life and social participation after acquired brain injury
2/17/2015 ... Self-efficacy and coping predict long-term QOL but seem less important in long-term social participation.
Reduced heart rate variability in traumatic brain injury and association with impaired emotional and social functioning
2/20/2015 ... HRV was positively associated with social cognition and empathy.
2/23/2015 ... The rate of psychological symptoms was significantly higher post-TBI than pre-TBI.
2/25/2015 ... Evidence of a direct relation between sleep-wake disturbances and traumatic brain injury, and for clinically significant underestimation of post-traumatic sleep-wake disturbances by trauma patients.
Associations between executive functioning, coping, and psychosocial functioning after acquired brain injury
2/27/2015 ... Individuals who report difficulties with executive functioning after ABI may be inclined to use passive coping styles, which are maladaptive.
3/11/2015 ... Qualitative analysis indicated that caregivers were most concerned about their social health (42% of comments).
3/12/2015 ... Personality change was observed in most patients with severe brain injury. Change in neuroticism was associated with frontal and temporal lesions.
3/23/2015 ... A history of TBI increases the risk of problems with the experience, expression, and control of anger.
4/9/2015 ... These findings demonstrate the long-term PTSD effects that can occur following traumatic injury.
4/10/2015 ... Incidence of TBI demonstrated increased risk of developing an AUD within 1 year of incident TBI.
4/13/2015 ... When task difficulty is taken into account, individuals with TBI show impairment in recognizing all facial emotions.
4/14/2015 ... The cognitive impairments present following TBI are probably exacerbated by poor sleep quality and sleep deprivation during hospitalisation, which in turn impact ADLs among this population.
PTH may well play a significant role in the progressive signs and symptoms that follow a chronic TBI.
College students with ABI are vulnerable to reading comprehension problems.
4/27/2015 ... Individuals with more functional impairments are at risk for decreases in life satisfaction over time.
4/29/2015 ... The Physical Functioning domain showed statistically significant improvements across time.
Relationship between resilience, adjustment, and psychological functioning after traumatic brain injury
5/14/2015 ... Individuals with TBI are at risk for low resilience, which was found to correlate with psychological distress and psychosocial maladjustment.
5/19/2015 ... TBI causes persisting intelligence impairments, where children may have better recovery from mild TBI and poorer recovery from severe TBI than adults.
5/20/2015 ... Female patients with MTBI had lower digit span scores than did female control subjects, and functional MR imaging depicted sex differences in working memory functional activation.
5/26/2015 ... The results support that mTBI is distinguished from moderate-to-severe TBI in terms of risk for developing neuropsychiatric disorders.
6/1/2015 ... The results indicate a less efficient performance over time in complex and demanding cognitive tasks for individuals experiencing from mental fatigue after brain injury.
6/5/2015 ... Head injury was not associated with faster disease progression in ALS and did not result in a specific neuropathologic phenotype.
6/17/2015 ... These results indicate a difference in the magnitude and nature of perceived sleep disturbance after mTBI compared with controls, where persons with mTBI report poorer sleep quality and greater sleep-related impairment.
Relatives of patients with severe brain injury: Growth curve analysis of anxiety and depression the first year after injury
6/26/2015 ... Higher initial level of anxiety was associated with younger patient age, lower level of function and consciousness in the patient and the relative being female or the spouse.
6/30/2015 ... Damage in the frontal and temporal lobes, gyrus rectus, and insula was associated with greater behavioral disinhibition.
7/13/2015 ... Subacute complications occurred in two-thirds of patients. Presence of a tracheostomy or epilepsy at 3 weeks, and of PEG feeding and weight loss at 3 months, had robust associations with unfavourable outcome.
Associated mental illness symptoms in close relatives of patients with severe traumatic brain injury
7/30/2015 ... This study quantifies an extraordinarily high prevalence of mental illness symptoms in close relatives of patients with critical acquired brain injury.
The impact of traumatic brain injury on self-identity: A systematic review of the evidence for self-concept changes
8/3/2015 ... People with TBI most commonly experience negative changes in self-identity.
8/4/2015 ... The TBI-related brain lesions have a lasting effect on long-term caregiver burden due to cognitive and behavioral factors associated with dysexecutive syndrome.
Conversational synchrony in the communicative interactions of individuals with traumatic brain injury
8/6/2015 ... Results suggest that TBI can disrupt conversational synchrony and can, in turn, negatively impact social perceptions.
8/27/2015 ... TBI significantly increased the risk of depression among older adults, especially among men and those discharged to a skilled nursing facility.
9/10/2015 ... The findings show that even drivers with mild TBI have significantly
longer and more glances toward the tasks compared to the healthy controls.
Personality change due to traumatic brain injury in children and adolescents: Neurocognitive correlates
9/11/2015 ... Attention, processing speed, verbal memory, IQ, and executive function were significantly associated with personality change.
9/14/2015 ... Our findings offered evidence of an association between TBI and suicidal ideation among male OEF/OIF VHA users.
9/16/2015 ... Over the first four years postinjury 17.6% developed injury-related PTSD, none of whom had PTSD prior to injury.
The results support a modest causal link between TBI and criminality after comprehensive adjustment for confounding.
9/21/2015 ... A high prevalence of vision diagnoses (accommodative, binocular convergence, and saccadic eye movement disorders) was found in this sample of adolescents with concussion, with some manifesting more than one vision diagnosis.
9/23/2015 ... Anxiety is common after a TBI and ongoing monitoring and treatment should be provided.
9/30/2015 ... Damage in the frontal and temporal lobes, gyrus rectus, and insula was associated with greater behavioral disinhibition.
Associations between a history of traumatic brain injuries and current cigarette smoking, substance use, and elevated psychological distress
10/2/2015 ... Adults who reported a history of TBI had higher odds of reported daily smoking, using cannabis and nonmedical opioids, as well as screened significantly for recent elevated psychological distress.
A comparison of adult outcomes for males compared to females following pediatric traumatic brain injury
10/5/2015 ... Females were significantly more likely than males to report a history of internalizing problems, whereas males were more likely than females to report externalizing problems.
10/13/2015 ... Significant positive associations between lifetime TBI and both current and past ADHD were observed among adults in this population.
10/15/2015 ... History of TBI, including mild TBI, is associated with the development of neurological and psychiatric illness.
10/16/2015 ... Findings demonstrate both the presence and persistence of oculomotor-based changes, suggestive of neural plasticity even in the adult, compromised brain.
A qualitative study of the reasons why people choose to tell or not tell others about their traumatic brain injury
10/19/2015 ... Disclosure can have important advantages and disadvantages. Some people with a TBI may need support in making optimal decisions about disclosure.
10/22/2015 ... Results indicate that poor subjective sleep quality is a significant problem in those with mTBI.
Associations between brain-derived neurotrophic factor, memory impairment, functional cognition, and depressive symptoms following TBI
10/27/2015 ... Acute BDNF associations with memory recovery may implicate hippocampal damage/degeneration.
10/28/2015 ... Veterans with history of TBI, of any severity, and current insomnia
symptoms may be at increased risk for depression and anxiety 1 year after TBI.
11/02/2015 ... Individuals who have PLC during the first year after TBI are more likely to have any psychiatric diagnosis as well as higher rates of mood and anxiety symptoms.
11/11/2015 ... Cognitive functioning was found to predict agitation, medications that have been found in previous studies to enhance cognition were associated with less agitation, and medications that can potentially suppress cognition were associated with more agitation.
11/16/2015 ... One year post injury, 41.4% of people were identified as having clinically significant sleep difficulties, with 21.0% at a level indicative of insomnia.
Early CT frontal abnormalities predict long-term neurobehavioral problems after traumatic brain injury
11/17/2015 ... Early CT frontal abnormalities predict long-term neurobehavioral problems, but not affective problems.
11/18/2015 ... This is the first population-based study to demonstrate a relationship between a history of TBI and higher rates of serious driver aggression and collision involvement.
Spatial neglect hinders success of inpatient rehabilitation in individuals with traumatic brain injury
12/16/2015 ... Spatial neglect is common following TBI, impedes rehabilitation progress in both motor and cognitive domains, and prolongs length of stay.
12/18/2015 ... The risk for epileptic seizures was substantially increased after TBI, especially during the first 6 months after the injury and in patients with a combination of ICH and brain contusion.
12/21/2015 ... Premorbid variables, especially pre-TBI felonies, were strongly linked to post-TBI criminal arrests.
12/23/2015 ... These results disclose that women with TBI do not fare as well as controls in these measures of sexual functioning and were less sexually satisfied.
12/30/2015 ... Men with TBI showed a tendency towards the reduction of sociosexuality. TBI does not seem to have an impact on infidelity
1/13/2016 ... Some adults with TBI have difficulty assessing the level of sincerity of speakers. Moreover, poorer social cognition abilities are associated with this difficulty.
1/22/2016 ... These findings demonstrate that perceptual organization is diffusely affected in TBI and this effect has no substantial correlations with IQ.
1/26/2016 ... The use of hypnotics is associated with an increased risk of dementia in TBI patients with or without insomnia, whereas insomnia alone is not.
1/28/2016 ... TBI may have an enduring effect on the orienting system at both neural and behavioural levels.
2/3/2016 ... Significant positive associations between lifetime TBI and both current and past ADHD were observed among adults in this population.
2/4/2016 ... Results indicate that poor subjective sleep quality is a significant problem in those with mTBI.
Conversational synchrony in the communicative interactions of individuals with traumatic brain injury
2/9/2016 ... TBI can disrupt conversational synchrony and can, in turn, negatively impact social perceptions.
2/11/2016 ... We show that PTA is intimately related to olfactory problems following a TBI.
2/16/2016 ... TBI was associated with a higher risk of both bipolar disorder and major depression.
2/19/2016 ... OD was relatively common in this paediatric TBI cohort and the hypothesized relationship with severity of injury was supported.
2/22/2016 ... Life role participation and depressive symptoms were strong predictors of life satisfaction trajectories across the first 5 years post-TBI.
3/2/2016 ... The evidence suggests that TBI is associated with widespread objective and subjective sleep deficits.
3/3/2016 ... A significant increase in consumption was noted by 6 months post-injury, followed by more gradual increases in alcohol consumption at 1 year.
3/8/2016 ... Avoidance coping increased
in the chronic phase after brain injury.
The relation between injury of the spinothalamocortical tract and pain in patients with mild traumatic brain injury
3/11/2016 ... Decreased FA and tract volume and increased MD of the STTs in the pain group appeared to indicate injury of the STT.
3/18/2016 ... Among adult patients with concussions, those with a higher symptom burden after injury have an increased odds of suffering from prolonged symptoms. Other potential predictor variables are not associated with the risk of prolonged recovery.
3/23/2016 ... Clinically significant anxiety was reported by 21% of participants. Of these, more than 80% reported interference with daily activities, with most common symptoms being excessive worry and irritability.
4/5/2016 ... Headache was more likely among individuals previously referred to a hospital for a mild head injury compared to uninjured controls.
4/19/2016 ... Individuals with TBI who failed an on-road assessment significantly
overestimated their driving ability.
Effects of depression and antidepressant use on cognitive deficits following severe traumatic brain injury
4/22/2016 ... These results suggest that antidepressant use impairs cognition among individuals without PTD.
4/28/2016 ... Osteopenia and osteoporosis are common in young adults with ABI compared with the general population.
5/2/2016 ... Patients who reported that their preinjury personality was depressive or anxious-related presented more PCS.
5/5/2016 ... Results suggest that impairment in the ability to update behavior when social reinforcement contingencies change plays a role in social disinhibition after TBI.
5/11/2016 ... A substantial number of patients encounter anxiety and depressive disorders following TBI, and that these problems persist over time.
Olfactory identification and its relationship to executive functions, memory, and disability one year after severe traumatic brain injury
5/13/2016 ... Individuals classified with anosmia by the B-SIT showed significantly lower scores for set-shifting, category switching fluency and delayed verbal memory.
Energy and protein deficits throughout hospitalization in patients admitted with a traumatic brain injury
5/18/2016 ... Patients admitted to ICU with a TBI have energy and protein deficits that persist after ICU discharge, leading to considerable shortfalls over the entire hospitalization.
5/19/2016 ... Vitamin D deficiency is common in patients after TBI and associated with impaired cognitive function and more severe depressive symptoms.
5/20/2016 ... Most patients with PCS had multiple symptoms persisting for months or years.
Relationships between risky sexual behaviour, dysexecutive problems, and mental health in the years following interdisciplinary TBI rehabilitation
5/25/2016 ... In individuals with TBI, risky sexual behaviour was associated with behavioural, cognitive and emotional dysexecutive problems, but not with anxiety or depression.
Axis I psychiatric disorders in the first 5 years following moderate to severe traumatic brain injury
5/26/2016 ... Findings suggest the first year post-injury is a critical period for the emergence of psychiatric disorders.
5/27/2016 ... The presented cases provide further support for the compounded risk of developing psychosis following TBI and cannabis use.
6/1/2016 ... Greater sexual dysfunction in spouses/partners was associated with older age and with poorer sexual functioning in the person with injury.
6/6/2016 ... While prevalence of headache is consistently high over the first year after injury, rate of depression increased over the first year for those who were followed.
6/8/2016 ... History of TBI, including mild TBI, is associated with the development of neurological and psychiatric illness.
6/14/2016 ... Twenty-four percent (24%) of patients viewed their marriage as unstable
as did 29% of partners.
6/16/2016 ... The results highlight discrepancies in participation in communication activities between people with TBI and people without TBI, suggesting the need for intervention studies to enhance communication participation in daily life following TBI.
6/22/2016 ... Caregivers of TBI survivors targeted personal concerns relating to their own emotional adjustment and participation as well as concerns relating to symptoms and recovery of the TBI survivor to address through education and problem-solving.
Longitudinal sex and stress hormone profiles among reproductive age and post-menopausal women after severe TBI
7/1/2016 ... The stress of TBI results in anovulation and central hypothalamic-pituitary-ovarian (HPG) axis suppression.
The relationship between sleep-wake cycle disturbance and trajectory of cognitive recovery during traumatic brain injury
7/12/2016 ... This study has implications for improving neurorehabilitation treatment, as targeting sleep dysfunction for early intervention may facilitate cognitive recovery.
7/15/2016 ... This study provides prospective, controlled, and objective evidence for chronic persistence of posttraumatic SWD, which remain underestimated by patients.
7/18/2016 ...The long-term psychiatric consequences of severe injury are substantial and represent a significant contributor to long-term disability.
Exploring the experience of sleep and fatigue in male and female adults over the 2 years following traumatic brain injury
Targeted support to understand, accept and manage the sleep and fatigue difficulties experienced may be crucial to improve recovery and facilitate engagement in everyday life.
Perseveration during verbal fluency in traumatic brain injury reflects impairments in working memory
7/27/2016 ... These results suggest that the perseverations produced during verbal fluency in individuals with TBI stem from the same working memory mechanism proposed in AD, rather than inhibitory control or word retrieval deficits.
An investigation of the impact of facial affect recognition impairments in moderate to severe TBI on fatigue, depression, and quality of life
7/28/2016 ... Individuals who have better FAR may require increased effort to perform this task, and thus experience greater fatigue and poorer social and emotional QoL.
7/29/2016 ... Depression, insomnia, and cognitive difficulties remain strong correlates of fatigue, while for pain and work status the association with fatigue evolves over time.
A prospective examination of Axis I psychiatric disorders in the first 5 years following moderate to severe traumatic brain injury
8/3/2016 ... Findings suggest the first year post-injury is a critical period for the emergence of psychiatric disorders. Disorder frequency declines thereafter, with anxiety disorders showing greater resolution than mood and substance-use disorders.
8/4/2016 ... Functional interactions of the executive and salience networks were related to emotion regulation and complaints after mTBI, with a key role for the bilateral frontal network.
8/8/2016 ... a substantial number of patients encounter anxiety
and depressive disorders after TBI, and that these problems persist over time.
The TBI patients also showed strong positive correlations between boredom proneness and measures of physical aggression and anger.
8/19/2016 ... OD is a prevalent but underdiagnosed problem in mTBI.
8/24/2016 ... The findings suggest that psychological variables are important in the development of SA following TBI and must be considered alongside clinical factors.
8/29/2016 ...As a significant contributor to neurobehavioral symptoms, treatment for post-injury sleep-related impairment warrants further attention.
9/1/2016 ... A history of mild TBI is more frequently observed in CHR individuals than in HC.
Hyposmia, not emotion perception, is associated with psychosocial outcome after traumatic brain injury
These results support previous claims that hyposmia has prognostic significance following TBI.
9/14/2016 ...Trajectories based on LCGMM are an empirical and clinically meaningful way to characterize distinct courses of depression after TBI.
9/16/2016 ...Greater sexual dysfunction in spouses/partners was associated with older age and with poorer sexual functioning in the person with injury.
9/20/2016 ...TBI survivors and caregivers had multiple self-reported unaddressed needs following their discharge from facility-based treatment.
Amused, flirting or simply baffled? Is recognition of all emotions affected by traumatic brain injury?
9/21/2016 ...Emotion recognition deficits are a direct consequence of TBI and have a direct effect on the social dysfunction which is a common outcome of TBI, strengthening the need for targeted remediation.
9/26/2016 ... The largest effect size indicated
that the odds of returning to work successfully are more than cut in half for each unit increase in NPRS rating.
9/27/2016 ... Students with TBI do not accurately perceive how others perceive their behavior.
9/30/2016 ... Most agitated behaviours in the early phase are transient and are not associated with poor outcome.
A biopsychosocial analysis of sexuality in adult males and their partners after traumatic brain injury
10/3/2016 ... After male severe TBI, men appear to have a reduced quality of their
sexual life, which may be more a result of relationship dysfunction than a sexual
performance deficit related to their brain injury history.
Early changes in cortical emotion processing circuits after mild traumatic brain injury from motor vehicle collision
10/4/2016 ...These results suggest that early differences in activation and structure in cortical emotion processing circuits in trauma survivors who sustain mTBI may contribute to the development of emotion-related symptoms.
10/7/2016 ... Individuals institutionalized after inpatient rehabilitation for TBI were older, lived alone before injury, had longer posttraumatic amnesia durations, and were less independent in specific functional characteristics.
"I've never been a yes person": Decision-making participation and self-conceptualization after severe traumatic brain injury
11/10/2016 ... This study identified that decision-making experiences play an important role in the ongoing process of self-conceptualization after injury.
11/11/2016 ... Compared to the general population, individuals with TBI are at
greater risk for depression and suicidal behaviour many years after TBI.
11/14/2016 ... Cognitive and physical fatigue are problematic symptoms following mild-moderate TBI that are differentially associated with specific injury and psychiatric sequelae.
11/15/2016 ... Over 1 year, most individuals with mTBI or cmTBI regain MDC, while many individuals with msevTBI have lingering deficits in reasoning and comprehension of treatment information.
11/17/2016 ... Those with a past-year TBI demonstrated significantly elevated rates of
illicit drug use relative to non-injured Canadians.
11/21/2016 ... The data in this study indicate that TBI is significantly associated with the subsequent risk of SRD.
11/23/2016 ... Results show that prolonged sleep deprivation can be observed after TBI, and suggest that the hospital environment only partially contributes to sleep-wake disturbances.
11/28/2016 ... Normative comparisons revealed that approximately one-third of individuals with TBI and one-fifth of their partners scored below the second percentile.
11/29/2016 ... Fatigue is a persistent symptom after traumatic brain injury. It is often undervalued.
12/13/2016 ... Overall, fathers reported greater depression and general distress than
mothers 18 months after injury, but not at long-term follow-up.
Subacute posttraumatic complaints and psychological distress in trauma patients with or without mild traumatic brain injury
1/5/2017 ... Patients with mTBI showed a different pattern of complaints than
orthopaedic control patients.
1/19/2017 ... Results added further evidence of social communication problems in adults with TBI and demonstrated that discourse
behaviours may negatively affect how a speaker is perceived.
Growth hormone deficiency and hypopituitarism in adults after complicated mild traumatic brain injury
1/20/2017 ... Patients examined at 1 year or several years from complicated mild
TBI had a similarly high occurrence of isolated GH deficiency, which was
associated with visceral adiposity and metabolic alterations.
2/1/12 ... Describes a new model of the adaptation process following acquired brain injury, based on the patient’s goals, the patient’s abilities and the emotional response to the changes and the possible discrepancy between goals and achievements.
2/8/12 ... A clinical pathway can improve the quality of care for all admissions with head injury and enhance the role for rehabilitation at an early stage.
2/9/12 ... To evaluate all the possible therapeutic measures concerning the acute management of traumatic brain injury (TBI) mentioned in Cochrane Systematic Reviews published in the Cochrane Database of Systematic Reviews (CDSR).
2/20/12 ... In this review, the critical care management of severe TBI will be discussed with focus on monitoring, avoidance and minimization of secondary brain insults, and optimization of cerebral oxygenation and CPP.
2/21/12 ... study investigating the effectiveness of a 12-weekly anxiety treatment programme adapted for individuals with moderate-severe TBI, based on cognitive behaviour therapy (CBT) and Motivational Interviewing (MI).
2/22/12 ... A new drug is showing promise in shielding against the harmful effects of traumatic brain injury (TBI) in rats.
2/28/2012 ... Driving cessation following TBI is associated with emotional, identity, transport and participation-related needs. An ongoing, individualised approach involving information, support and practical experiences may improve outcomes of driving cessation for people with TBI and their family members.
3/1/2012 ... Although some guidelines are offered for PTHA management based on primary headache categories and treatments, no strong evidence from clinical trials is available to direct the treatment of PTHA.
3/7/2012 ... In every age group aggressive care resulted in better outcomes (more quality-adjusted years) than routine care, and routine care resulted in better outcomes than comfort care.
3/19/2012 ... Physical exercise diminishes cerebral inflammation by elevating factors and agents involved in immunomodulatory function, and buttresses glial cell, cerebrovascular, and blood–brain barrier intactness.
3/23/2012 ... Immediate skull reconstruction following trauma that penetrates or creates an indentation in the skull can aggravate brain damage inflicted by the initial injury.
Cognitive behavior therapy after acquired brain injury: Maintenance of therapeutic benefits at 6 months posttreatment
4/3/2012 ... The CBT adapted for ABI shows enduring benefits for mood and community integration.
Pharmacotherapy regimens among patients with posttraumatic stress disorder and mild traumatic brain injury
4/4/2012 ... The differences in drug therapy found in this study may indicate that patients with TBI and PTSD respond differently to treatment than patients with PTSD alone.
4/9/2012 ... The treatment model represented by the ASMT appears worthy of further study in persons with TBI who have both problematic anger and cognitive impairment.
Acupuncture for treatment of insomnia in patients with traumatic brain injury: A pilot intervention study
4/12/2012 ... Acupuncture has a beneficial effect on perception of sleep or sleep quality and on cognition in our small sample of patients with TBI.
Use of hyperbaric oxygen in traumatic brain injury: Retrospective analysis of data of 20 patients treated at a tertiary care centre
4/19/2012 ... After the treatment, a significantly higher proportion of HBOT treated subjects showed a good response in cognitive functions, as measured by RLA.
4/25/2012 ... Estrone, one of the three naturally occurring estrogen hormones in the body, has shown some promise in reducing inflammation and cell death in the brain.
5/2/2012 ... The low methodological quality of the included studies does not allow us to make conclusive judgments on the efficacy and safety of acupuncture in either the acute treatment and/or rehabilitation of TBI. Its beneficial role for these indications remains uncertain.
5/10/2012 ... Current cumulative evidence does not support general use of therapeutic hypothermia for acute severe TBI. However, further investigation of the role of therapeutic hypothermia may be warranted for specific TBI subgroups.
Effectiveness of chin-down posture to prevent tracheal aspiration in dysphagia secondary to acquired brain injury. A videofluoroscopy study
5/14/2012 ... Only half the patients with acquired brain injury avoided aspiration during cervical flexion; 48% of silent aspirators continued to aspire during the maneuver. Several videofluoroscopic parameters were related to inefficiency of the maneuver.
5/16/2012 ... Overall, findings suggest that mentoring can be beneficial toward achieving the goals of post-secondary education, employment and community independence for individuals with disabilities; specifically those with traumatic brain injury, spinal cord injury and other neurological disorders.
5/22/2012 ... There is evidence to support the benefits of a wide range of models of specialist VR after TBI.
5/30/2012 ... TAU research finds that existing diabetes medication may ease damage caused by brain-addling explosions.
6/1/2012 ... Physical exercise reinforces the adaptive processes of the brain that has undergone TBI thereby facilitating the development of existing networks.
6/4/2012 ... In a step towards improving rehabilitation for patients with walking impairments, researchers from the Kennedy Krieger Institute found that non-invasive stimulation of the cerebellum, an area of the brain known to be essential in adaptive learning, helped healthy individuals learn a new walking pattern more rapidly.
6/14/2012 ... Surgical resection of heterotopic ossification of the shoulder is an effective procedure to increase joint mobility and improve function.
Aripiprazole improves various cognitive and behavioral impairments after traumatic brain injury: a case report
6/19/2012 ... In the present case, aripiprazole dramatically improved the patient's symptoms and cognitive function.
6/22/2012 ... Levetiracetam and Phenytoin demonstrate equal efficacy in seizure prevention after brain injury. However, very few randomized controlled trials (RCTs) on the subject were found.
7/5/2012 ... Although this data unequivocally shows that VNS improves outcome from TBI in animal models, it remains to be determined if these findings translate clinically.
Aripiprazole improves various cognitive and behavioral impairments after traumatic brain injury: a case report
7/18/2012 ... Aripiprazole dramatically improved the patient's symptoms and cognitive function.
7/23/2012 ... The best available evidence suggests that complete rest exceeding 3 days is probably not helpful, gradual resumption of preinjury activities should begin as soon as tolerated (with the exception of activities that have a high MTBI exposure risk), and supervised exercise may benefit patients with persistent symptoms.
Repetitive transcranial magnetic stimulation for the treatment of chronic tinnitus after traumatic brain injury
7/24/2012 ... Repetitive transcranial magnetic
stimulation was tolerated without any side effects and tinnitus complaints
(measured by a validated tinnitus questionnaire and numeric rating scales) were improved in a replicable way throughout 5 courses of transcranial magnetic stimulation up to now.
Examining the effect of mindfulness-based stress reduction on symptoms of chronic mild traumatic brain injury/postconcussive syndrome
7/24/2012 ... The MBSR program can be adapted for
participants with mTBI. Improved performance on measures associated with improved
quality of life and self-efficacy may be related to treatment directed at improving awareness and acceptance, thereby minimizing the catastrophic assessment of symptoms associated with mTBI and chronic disability.
7/25/2012 ... A therapeutic construct for treatment of attention, perceptual processing, categorization and cognitive distance deficits is presented along with an interventional model for encouragement of re-emergence or regeneration of these fundamental information processing skills.
7/31/2012 ... This kind of therapy was shown
to be feasible, with a high rate of compliance (72%). Psycho-affective disorders and hostility were shown to be more sensitive to therapy than other behaviour impairments.
Insight vs readiness: Factors affecting engagement in therapy from the perspectives of adults with TBI and their significant others
8/1/2012 ... Participants reported that it was important to be able to access services when they had accepted their impairment and were ready to engage in therapy.
8/3/2012 ... Prophylactic anti-epileptics are effective in reducing early seizures, but there is no evidence that treatment with prophylactic anti-epileptics reduces the occurrence of late seizures, or has any effect on death and neurological disability.
Effect of analgesics and sedatives on the occurrence of spreading depolarizations accompanying acute brain injury
10/2/2012 ... Findings suggest that ketamine-or another N-methyl-d-aspartate receptor antagonist-may represent a viable treatment for patients at risk for spreading depolarizations.
Who responds better? Factors influencing a positive response to brief alcohol interventions for individuals with traumatic brain injury
10/18/2012 ... Investigation of variables associated with the frequency and quantity
of alcohol consumption following a brief alcohol intervention in individuals with
traumatic brain injury.
11/2/2012 ... Cerebrovascular dysfunction, manifested by reduction in cerebral blood flow (CBF), is a key factor that worsens outcome after traumatic brain injury (TBI), most notably under conditions of hypotension.
12/5/12 ... This study showed that HBO2 at 2.4 ATA pressure had no effect on post-concussive symptoms after mild TBI.
12/31/2012 ... This study showed that HBO(2) at 2.4 ATA pressure had no effect on post-concussive symptoms after mild TBI.
1/10/2013 ... The results suggest that the video plus verbal feedback approach used in this study was effective in improving self-awareness in people with TBI.
1/21/2013 ... There is no evidence that barbiturate therapy in patients with acute severe head injury improves outcome.
Acupuncture helps regain postoperative consciousness in patients with traumatic brain injury: A case study
1/24/2013 ... There is the possibility that an experienced physician may use acupuncture as complementary therapy in patients with TBI who fail to regain consciousness postoperatively.
The application of Goal Management Training to aspects of financial management in individuals with traumatic brain injury
2/1/2013 ... Overall the results showed that the structured GMT intervention assisted some TBI individuals to improve their performance on financial management tasks, with evidence of generalisation in
2/28/2013 ... Sleep disorders have a major impact on health outcomes in patients with TBI. To optimize rehabilitation and ultimately improve functional outcomes of patients with TBI, implementation of evidence-based clinical guidelines for sleep is imperative.
3/1/2013 ... Addition of cognitive-motor
dual-task training to standard physical therapy in the inpatient rehabilitation
setting appears to be feasible and may have value for improving function in
individuals with severe TBI.
Role of therapeutic hypothermia in improving outcome after traumatic brain injury: a systematic review
3/6/2013 ... Given the quality of the data currently available, no benefit of PTH on mortality or neurological morbidity could be identified. The therapy should therefore only be used within the confines of well-designed clinical trials.
3/19/2013 ... These data underscore the critical importance of timing of exercise initiation after trauma and its
relation to neuroinflammation, and challenge the widely held view that effective neuroprotection requires early intervention.
Cognitive behavioural therapy for depression and anxiety in adults with acquired brain injury. What works for whom?
3/26/2013 ... This review suggests that if CBT is aimed at, for example, anger management or coping, it can be effective for anger or coping, but will not generalise to have an effect on anxiety or depression.
4/2/2013 ... Administration early in the course of treatment, in the emergency department or sooner, has the potential to improve outcomes from this potentially devastating public health problem.
Aripiprazole improves various cognitive and behavioral impairments after traumatic brain injury: a case report
4/3/2013 ... In the present case, aripiprazole dramatically improved the patient's symptoms and cognitive function.
4/15/2013 ... Enzogenol supplementation is safe and well tolerated in people after mild TBI, and may improve cognitive functioning in this patient population.
4/25/2013 ... Here we show that cardiac and temperature autonomic function are compromised during the subacute period following a mild TBI.
A range of antiepileptic drugs do not affect the recovery of consciousness in vegetative and minimally conscious states
4/26/2013 ... AEDs did not affect the recovery of consciousness in a large cohort
of patients in a VS or MCS following an acute brain injury.
Nutritional support for patients sustaining traumatic brain injury: a systematic review and meta-analysis of prospective studies
5/2/2013 ... After TBI, early initiation of nutrition is recommended. It appears
that parenteral nutrition is superior to enteral nutrition in improving outcomes.
Allogenic umbilical cord blood therapy combined with erythropoietin for patients with severe traumatic brain injury
5/6/2013 ... The allogenic UCB therapy combined with rhEPO in the present study
was safe and suggested potential therapeutic efficacy for patients with TBI.
A prospective, randomized Phase II clinical trial to evaluate the effect of combined hyperbaric and normobaric hyperoxia on cerebral metabolism, intracranial pressure, oxygen toxicity, and clinical outcome in severe traumatic brain injury
5/8/2013 ... There was significant
reduction in mortality and improved favorable outcome as measured by GOS. The
combination of HBO2 and NBH therapy appears to have potential therapeutic
efficacy as compared with the 2 treatments in isolation.
Vocational rehabilitation for clients with cognitive and behavioral disorders associated with traumatic brain injury.
5/16/2013 ... Despite a high prevalence of cognitive and behavioral disorders after moderate-to-severe TBI, long-term functional improvement is likely to occur in clients with TBI.
Effect of frequency of multimodal coma stimulation on the consciousness levels of traumatic brain injury comatose patients
5/24/2013 ... The results showed a significant difference (p < 0.01) for Glasgow Coma Scale as well as Western Neuro Sensory Stimulation Profile scores between Groups A & C and B & C, i.e. multimodal coma stimulation is effective as compared to the control group.
6/3/2013 ... Zolpidem is an effective medicine to restore brain function in patients in vegetative state after brain injury, especially for those whose brain injuries are mainly in non-brain-stem areas.
6/12/2013 ... This article highlights the usefulness of psychotherapy for treatment of psychiatric symptoms in the TBI population.
Vagus nerve stimulation to augment recovery from severe traumatic brain injury impeding consciousness
7/16/2013 ... If this study demonstrates that VNS can safely and positively impact outcome, then a larger randomized prospective crossover trial will be proposed.
8/7/2013 ... Contrary to the main aim, the use of a family-focused intervention did not result in self-concept improvement, either globally or across self-concept domains.
8/8/2013 ... Results suggest that Cerebrolysin improves the cognitive function of the MTBI in patients at 3rd month after injury, especially for long-term memory and drawing function.
8/12/2013 ... Our preliminary data suggest that CBT delivered soon after mild traumatic brain injury is well tolerated and may facilitate recovery in patients who are at risk for chronic PCS.
8/20/2013 ... The results suggest that the video plus verbal feedback approach used in this study was effective in improving self-awareness in people with TBI.
A preliminary study using attention process training-3 and Lumosity™ brain games to remediate attention deficits following traumatic brain injury
9/9/2013 ... Findings call into question the assumption that intervention using either APT-3 or Lumosity™ will prompt generalization beyond the actual tasks performed during treatment.
9/16/2013 ... Replacement therapy can improve cognition and QoL in patients with TBI who have GHD, especially in those with severe disabilities.
A multidimensional physical therapy program for individuals with cerebellar ataxia secondary to traumatic brain injury
9/24/2013 ... The three individuals with cerebellar ataxia participated in a long-term, individualized, multidimensional physical therapy treatment program, and made improvements in all areas of impairment and activity limitations.
Effect of progesterone administration on prognosis of patients with diffuse axonal injury due to severe head trauma
10/1/2013 ... The use of progesterone may significantly improve neurologic outcome of patients suffering severe TBI up to 3 months after injury, especially those with 5≤GCS≤8, providing a potential benefit to the treatment of acute severe TBI.
Training communication partners of people with severe traumatic brain injury improves everyday conversations
10/16/2013 ... Training communication partners of people with chronic severe traumatic brain injury was more efficacious than training the person with traumatic brain injury alone.
Mobile phone text messaging to assess symptoms after mild traumatic brain injury and provide self-care support
10/25/2013 ... Those receiving the text messaging-based education and support had fewer and less severe postconcussive symptoms than the controls but none of the differences reached statistical significance.
10/31/2013 ... In general, the use of glibenclamide to control plasma glucose after TBI had no significant effect on patient outcome at discharge.
11/11/2013 ... Race and insurance are strong predictors of discharge to rehabilitation among adult TBI survivors in the US.
11/13/2013 ... Data show that treatment using dietary and parenteral zinc supplementation can reduce TBI-associated depression and improve cognitive function, specifically spatial learning and memory.
Umbilical cord stem cell transplantation significantly improves neurological function in patients with traumatic brain injury
11/14/2013 ... Results confirmed that the umbilical cord mesenchymal stem cell transplantation improved the neurological function and self-care in patients with TBI.
11/18/2013 ... Video modelling could well be added within the rehabilitation programmes for this population.
Decreased risk of acute kidney injury with intracranial pressure monitoring in patients with moderate or severe brain injury
11/19/2013 ... In patients with moderate and severe TBI, ICP-directed mannitol treatment demonstrated a beneficial effect on reducing the incidence of AKI compared with treatment directed by neurological signs and physiological indicators.
11/25/2013 ... Alterations in diet and nutritional strategies have been shown to decrease both morbidity and mortality after injury.
12/3/2013 ... Encouraging observation to imitate may favor the transformation of some perceived actions into motor images and performances, probably depending on the activation of mirror motor neurons.
12/4/2013 ... Enzogenol supplementation is safe and well tolerated in people after mild TBI, and may improve cognitive functioning in this patient population.
Environmental enrichment may protect against hippocampal atrophy in the chronic stages of traumatic brain injury
12/12/2013 ... Clinical application of EE should be considered for optimal maintenance of neurological functioning in the chronic stages of moderate-severe TBI.
12/23/2014 ... This study demonstrated that HBO2 at either 1.5 or 2.0 ATA equivalent had no effect on postconcussion symptoms after mild traumatic brain injury when compared with sham compression.
Mindfulness-based cognitive therapy reduces symptoms of depression in people with a traumatic brain Injury
12/30/2013 ... These results are consistent with those of other researchers that use mindfulness-based cognitive therapy to reduce symptoms of depression.
Cognitive activity limitations one year post-trauma in patients admitted to sub-acute rehabilitation after severe traumatic brain injury
1/9/2014 ... The results of the current study suggest that absence of consciousness at discharge from acute care should not preclude patients from being referred to specialized sub-acute rehabilitation.
Umbilical cord mesenchymal stem cell transplantation significantly improves neurological function in patients with sequelae of traumatic brain injury
1/16/2014 ... All in all, the study results confirmed that the umbilical cord mesenchymal stem cell transplantation improved the neurological function and self-care in patients with TBI sequels.
Repetitive transcranial magnetic stimulation for the treatment of chronic tinnitus after traumatic brain injury
1/23/2014 ... Repetitive transcranial magnetic stimulation was tolerated without any side effects and tinnitus complaints (measured by a validated tinnitus questionnaire and numeric rating scales) were improved in a replicable way throughout 5 courses of transcranial magnetic stimulation up to now.
Effects of probiotics on blood glucose levels and clinical outcomes in patients with severe craniocerebral trauma
2/11/2014 ... Probiotics could facilitate blood glucose control in patients with severe craniocerebral injury.
Effects of glucocorticoids on traumatic brain injury related critical illness-related corticosteroid insufficiency
2/14/2014 ... This meta-analysis suggests an increased risk of death for TBI patients on a high dose and short term of glucocorticoids compared with those on a low dose and long term, for whom a trend towards clinical improvement is evident.
3/7/2014 ... Splenectomy was independently associated with increased mortality in patients with moderate or severe TBI.
3/20/2014 ... OBVR had a strong positive effect on oculomotor control, reading rate, and overall reading ability.
3/21/2014 ... Educating clients about their likelihood and timing of return to driving, and supporting non-drivers and their carers may improve psychosocial outcomes.
3/31/2014 ... Acute administration of omega-3 PUFAs after injury and dietary exposure before or after injury improve neurological outcomes in experimental SCI and TBI.
Effectiveness of amantadine in the reduction of chronic traumatic brain injury irritability and aggression
4/1/2014 ... Amantadine 100 mg every morning and at noon appears an effective and safe means of reducing frequency and severity of irritability and aggression among individuals with TBI.
4/11/2014 ... The robust effect of RP among TBI survivors with severe memory impairment engenders confidence that this strategy would work outside the laboratory to improve memory in real-life settings.
4/17/2014 ... Blue light therapy appears to be effective in alleviating fatigue and daytime sleepiness following TBI and may offer a noninvasive, safe, and nonpharmacological alternative to current treatments.
4/18/2014 ... Neurofeedback is a promising treatment that warrants double-blind, placebo-controlled studies to determine its potential role in the treatment of traumatic brain injury.
4/22/2014 ... Results support the use of an arts-based intervention for youth with ABI to facilitate social skills and participation.
Race and insurance disparities in discharge to rehabilitation for patients with traumatic brain injury
4/23/2014 ... Race and insurance are strong predictors of discharge to rehabilitation among adult TBI survivors in the United States.
Impact of rehabilitation on functional outcome during the first year of moderate and severe traumatic brain injury
4/25/2014 ... All individuals improved significantly in the inpatient rehabilitation facility in the acute phase.
5/6/2014 ... Cerebrolysin improves the cognitive function of the MTBI in patients at 3rd month after injury, especially for long-term memory and drawing function.
Virtual reality-based therapy for the treatment of balance deficits in patients receiving inpatient rehabilitation for traumatic brain injury
5/19/2014 ... This study provides a modest level of evidence to support using commercially available VR gaming systems for the treatment of balance deficits in patients with a primary diagnosis of TBI receiving inpatient rehabilitation.
Effectiveness of handheld computers for improving everyday memory functioning in patients with memory impairments after brain injury
5/23/2014 ... Occupational therapy training in the use of a handheld computer improved patients' daily memory function more than standard rehabilitation.
6/6/2014 ... Increased cognitive activity is associated with longer recovery from concussion.
Antiseizure prophylaxis after traumatic brain injury does not decrease seizure rates but may inhibit functional recovery
6/11/2014 ... PP may not decrease early posttraumatic seizure and may suppress functional outcome after blunt TBI.
7/1/2014 ... This study demonstrated that HBO2 at either 1.5 or 2.0 ATA equivalent had no effect on postconcussion symptoms after mild traumatic brain injury when compared with sham compression.
7/15/2014 ... Administration of the prostacyclin analogue epoprostenol significantly decreased CRP and, to some extent, IL-6 levels in patients with severe TBI.
Racial/ethnic and insurance status disparities in discharge to posthospitalization care for patients with traumatic brain injury
7/18/2014 ... Results suggest that racial/ethnic and insurance disparities exist in discharge to postacute care after hospitalization for traumatic brain injury.
7/21/2014 ... Patients with TBI receiving acupuncture treatment show decreased risk of stroke compared with those without acupuncture treatment.
8/4/2014 ... A preliminary study examining the effect of NMT in cognitive rehabilitation has reported promising results in improving executive functions along with improvement in emotional adjustment and decreasing depression and anxiety following TBI.
Brain activation by music in patients in a vegetative or minimally conscious state following diffuse brain injury
8/6/2014 ... The presence of STG activation by MS may predict a possible improvement of patients in a VS to MCS and fMRI employing MS may be a useful modality to objectively evaluate consciousness in these patients.
8/8/2014 ... Results indicate that a sub-group of people with TBI exists who restrict their outdoor activities. GPS has potential as an activity tracking tool, with implications for rehabilitation and exercise prescription.
9/3/2014 ... There are studies that demonstrate benefits of varying pharmacological and cognitive therapies for the management of attention problems after TBI.
Cost-effectiveness analysis of an early-initiated, continuous chain of rehabilitation after severe traumatic brain injury
9/9/2014 ... These findings indicate that the trajectory of continuous rehabilitation represents a dominant strategy in that it reduces costs and improves outcomes after TBI.
9/19/2014 ... Animal TBI models have suggested that alphalipoic acid, magnesium, taurine, coenzyme Q10, and many phytonutrients (such as resveratrol) are also helpful.
The effectiveness of handheld computers for improving memory functioning in patients with acquired brain injury
10/7/2014 ... Occupational therapy training in the use of a handheld computer improved patients' daily memory function more than standard rehabilitation.
10/9/2014 ... rTMS is safe, tolerated by most patients with mTBI, and associated with both a reduction in severity of PCS and an increase in task-related activations in DLPFC.
Telephone and in-person cognitive behavioral therapy for major depression after traumatic brain injury
10/22/2014 ... In-person and telephone administered CBT are acceptable and feasible in persons with TBI.
11/04/2014 ... Results from this study indicated that the IntenSati exercise program is a feasible and beneficial intervention for individuals with TBI as supported by the positive impact on their mood and quality of life.
11/12/2014 ... CFT was associated with a reduction in symptoms of anxiety and depression and associated self-criticism, as well as enhanced self-reassurance for TBI survivors.
11/25/2014 ... The EEG-NFT therapy has shown significant changes in structural and functional connectivity among young moderately injured TBI patients.
Development of self-awareness after severe traumatic brain injury through participation in occupation-based rehabilitation
12/04/2014 ... Engagement in occupation-based, goal-directed rehabilitation appeared to foster awareness of injury-related changes to varying extents.
12/10/2014 ... Walking can be used as an efficient and cost-effective tool to manage perceived stress and depressive symptoms in persons who have sustained a TBI.
12/12/2014 ... Use of a smartphone seems to be a satisfactory compensatory memory strategy to many patients with TBI and smartphones come with features that are advantageous to other compensatory strategies.
1/2/2014 ... Retrieved evidence for the effectiveness of melatonin for post pediatric ABI sleep impairment appears promising.
Improved cognitive performance following aerobic exercise training in people with traumatic brain injury
1/5/2015 ... Findings suggest that vigorous aerobic exercise training may improve specific aspects of cognitive function in individuals with TBI, and cardiorespiratory fitness gains may be a determinant of these improvements.
1/7/2015 ... Adult Hispanic and black patients with TBI are significantly less likely to receive intensive rehabilitation than their non-Hispanic white counterparts.
Effects of Hyperbaric Oxygen on Symptoms and Quality of Life Among Service Members With Persistent Postconcussion Symptoms
1/9/2015 ... Among service members with persistent PCS, HBO showed no benefits over sham compressions.
1/15/2015 ... The findings on the efficacy of these interventions were mixed, with only 10 studies showing some evidence of improvement in self-concept based on within-group or pre-post comparisons.
Comparison of cognitive behavioral therapy and supportive psychotherapy for the treatment of depression following traumatic brain injury
1/19/2015 ... Both forms of psychotherapy were efficacious in improving diagnoses of depression and anxiety and reducing depressive symptoms.
1/21/2015 ... Armodafinil 250 mg significantly improved sleep latency in patients with excessive sleepiness associated with mild or moderate TBI.
2/2/2015 ... This study indicated that applying naloxone in the early stage for TBI patients might effectively reduce mortality, control intracranial pressure (ICP), and significantly improve the prognosis.
2/9/2015 ... Primary and secondary efficacy analyses showed no clinical benefit of progesterone in patients with severe TBI.
Influence of intrathecal baclofen on the level of consciousness and mental functions after severe traumatic brain injury
2/10/2015 ... After severe brain injury, this treatment might trigger recovery from altered states of consciousness, improve cognition and facilitate rehabilitation.
2/11/2015 ... This case demonstrated that chiropractic treatment provided benefit to a patient with heterotopic ossification concurrent with musculoskeletal pain.
2/24/2015 ... The results from this study demonstrated that amantadine hydrochloride accelerates recovery in patients with severe TBI.
Growth Hormone Deficiency after Traumatic Brain Injury: improvement in quality of life with GH therapy
3/3/2015 ... GHR achieved clinically relevant, long-term benefit in Quality of Life.
3/24/2015 ... BoNT-A appears to be a potentially valuable tool in the chronic management of post craniotomy headache following traumatic brain injury.
3/26/2015 ... Donepezil itself enhances neurogenesis and improves cognitive function following TBI.
Evaluation of the effectiveness of a novel brain and vestibular rehabilitationt treatment modality in PTSD patients who have suffered traumatic brain injury
4/1/2015 ... Treatment of PTSD as a physical injury rather than a psychiatric disorder is associated with strong statistical and substantive significant outcomes.
Long-term caregiver mental health outcomes following online intervention for adolescents with traumatic brain injury
4/3/2015 ... Findings support the utility of Web-based interventions in improving long-term caregiver psychological distress, particularly for lower-income families.
4/7/2015 ... RMNS may serve as an easy, effective and non-invasive technique to promote the recovery of traumatic coma in the early phase.
Effect of social support and coping styles on the stress and mental health in relatives of patients with traumatic brain injury
4/17/2015 ... Social support and coping styles should be considered in psychological nursing program to prevent and adjust the mental distress in relatives of patients with traumatic brain injury, which is benefi cial to the treatment and recovery for patients.
4/22/2015 ... The result of this study of amantadine 100 mg every morning and noon to reduce irritability was not positive from the observer perspective.
Cumulative effects of transcranial direct current stimulation on attention/working memory after traumatic brain injury
5/4/2015 ... Results suggest that 10 anodal tDCS sessions may beneficially modulate regulation of cortical excitability for patients with TBI.
Study evaluating the effects of Cerebrolysin treatment on clinical outcomes in traumatic brain injury
5/11/2015 ... The results of this large retrospective study revealed that early Cerebrolysin treatment is safe and is associated to improved TBI outcome.
5/13/2015 ... Shock wave therapy resulted in pain relief and an improvement in the loss of motion in the left hip joint. Improvements were also noted in walking performance and activities of daily living.
5/22/2015 ... Through the quantitative EEG and the GCS observation score, music therapy in patients with craniocerebral trauma coma has obviously an effect on promoting to regain consciousness.
Glucose administration after traumatic brain injury exerts some benefits and no adverse effects on behavioral outcomes
5/25/2015 ... Results indicate that an early elevation of blood glucose may improve some neurological outcomes.
Videogame-based group therapy to improve self-awareness and social skills after traumatic brain injury
5/27/2015 ... Integrative videogame-based group therapy can improve self-awareness, social skills, and behaviors among individuals with chronic TBI, and the approach is considered effective and motivating.
6/2/2015 ... A combination of video plus verbal feedback is an effective technique for achieving maintained gains in self-awareness in people with TBI.
6/3/2015 ... A systematic review demonstrates an evolving evidence base to suggest some benefits in agitation and aggression, mood and attentional deficits.
6/8/2015 ... This study showed that RIC significantly decreased the standard biomarkers of acute brain injury in patients with severe TBI.
6/10/2015 ... No association was found between risk of malnutrition and severity of injury, complications, functional outcome, or length of stay.
Retrieval practice as an effective memory strategy in children and adolescents with traumatic brain injury
6/16/2015 ... We identify RP as a promising and simple strategy to support learning and improve memory in children and adolescents with TBI.
6/19/2015 ... Preliminary evidence for the effectiveness of 8mg of ramelteon taken nightly over a three week period was found in the treatment of sleep difficulties among individuals with TBI.
Family members facilitating community re-integration and return to productivity following traumatic brain injury
6/22/2015 ... Family members require on-going counseling and community supports to prevent burnout and allow for their continued engagement in their supportive roles.
7/3/2015 ... Adults with TBI appear to benefit in reading efficiency when simultaneously listening to and reading written passages.
7/20/2015 ... The current study showed that RMNS may serve as an easy, effective, and noninvasive technique to promote the recovery of traumatic coma in the early phase.
7/27/2015 ... The Faces Intervention effectively improved facial affect recognition in participants with chronic post-traumatic brain injury, and changes were maintained for 6 months.
7/28/2015 ... These findings provide preliminary evidence that the preferred music intervention may be effective as an environmental therapeutic approach for reducing agitation after TBI.
8/5/2015 ... Therapists are encouraged to value and invest in the development of relationships with clients whilst the importance of seeking and integrating the client perspective into practice and research is affirmed for the profession.
Effects of low-dose milnacipran on event-related potentials and neuropsychological tests in persons with traumatic brain injury
8/7/2015 ... Milnacipran administration improved ERP measures of attention and information processing in non-depressed persons with brain injury and also improved scores on three sub-scales of standard neuropsychological tests of cognitive dysfunction.
8/10/2015 ... Positive results for this case highlight the potential importance of massage therapy work to reduce headache, dizziness, and nausea in concussion recovery.
8/25/2015 ... Evidence from the present meta-analytic study suggests that occupation-based cognitive rehabilitation would be beneficial for individuals with TBI for improving daily functioning and positively be able to affect their psychosocial functions.
Feasibility and results of a case study of yoga to improve physical functioning in people with chronic traumatic brain injury
9/9/2015 ... Yoga, delivered in a one-to-one setting, appears to be feasible and beneficial to people with chronic TBI.
9/18/2015 ... Literature from 2004 to present generally concluded that amantadine improved cognitive function related to arousal, memory, and aggression.
Cognitive and psychological flexibility after a traumatic brain injury and the implications for treatment
9/22/2015 ... People with a traumatic brain injury (TBI) often suffer impairments in their cognitive flexibility as a result of damage to areas controlling executive processes but have a positive response to therapies that promote psychological flexibility.
10/8/2015 ... There is evidence that rTMS can be an effective treatment option for some post-TBI symptoms, such as depression, tinnitus, and neglect.
Treatments for traumatic brain injury with emphasis on transcranial near-infrared laser phototherapy
10/12/2015 ... NIR light in the power range of 10-15 W at 810 nm and 980 nm can safely and effectively treat chronic symptoms of TBI.
10/14/2015 ... Flexyx Neurotherapy System may be a potentially efficacious treatment for chronic posttraumatic headache.
10/20/2015 ... Together, our study suggested that progesterone did not improve outcomes over placebo in the treatment of acute TBI.
10/21/2015 ... Individuals with traumatic brain injury may benefit from internal memory strategy use, and clinicians should consider internal memory strategy instruction as part of intervention plans.
Can impaired working memory functioning be improved by Training? A Meta-Analysis With a Special Focus on Brain Injured Patients
11/5/2015 ... WM training produces long-lasting beneficial effects which are strongly pronounced in patients with acquired brain injuries.
11/12/2015 ... In general, lower admission FIM cognitive score groups were administered more of the medications under investigation compared with those with higher cognitive function at admission.
11/13/2015 ... This study provides preliminary evidence that there is significant institutional variation in rehabilitation practice and that center effects play a stronger role than patient factors in determining how TBI inpatient rehabilitation is delivered.
Long-term caregiver mental health following online intervention for adolescents with traumatic brain injury
11/20/2015 ... These findings support the utility of Web-based interventions in improving long-term caregiver psychological distress, particularly for lower-income families.
Decline in cognitive function due to diffuse axonal injury does not necessarily imply a corresponding decline in ability to perform activities
1/5/2016 ... The cognitive decline, caused by DAI, does not necessarily mean a concurrent decrease in activity performance, possibly explained by the use of compensatory strategies.
Physical therapy intervention strategies for patients with prolonged mild traumatic brain injury symptoms
1/8/2016 ... Physical therapy interventions for pediatric athletes with PCS may facilitate recovery and improve function.
1/15/2016 ... Pharmacotherapy after TBI may be associated with a reduction in depressive symptomatology.
1/20/2016 ... Despite some modest bias, present evidence demonstrated that progesterone was well tolerated but did not reduce the mortality or unfavorable outcomes of adult patients with acute TBI.
Transcranial magnetic stimulation facilitates neurorehabilitation after pediatric traumatic brain injury
2/1/2016 ... These results implicate TMS as a promising approach for reversing the adverse neuronal mechanisms activated post-TBI.
2/10/2016 ... This case adds to the medical literature by demonstrating the potential role of acupuncture in TBI treatment.
Individual differences in working memory capacity predicts responsiveness to memory rehabilitation after TBI
2/12/2016 ... Individuals with higher WMC showed a significantly greater rehabilitation benefit when applying the compensatory strategy to learn unorganized information.
3/1/2016 ... As much as 51 % of the elderly patients showed a favorable outcome after NIC.
Hyperbaric oxygen may induce angiogenesis in patients suffering from prolonged post-concussion syndrome due to traumatic brain injury
3/4/2016 ... HBOT may induce cerebral angiogenesis, which improves perfusion to the chronic damage brain tissue even months to years after the injury.
3/21/2016 ... Preliminary evidence suggests improvements in cognitive function following computerized rehabilitation for acquired brain injury populations including traumatic brain injury and stroke.
Efficacy of motivational interviewing and cognitive behavioral therapy for anxiety and depression symptoms following traumatic brain injury
3/22/2016 ... Findings suggest that modified CBT with booster sessions over extended periods may alleviate anxiety and depression following TBI.
3/28/2016 ... Results indicate that GH treatment is safe and effective for helping neurorehabilitation in TBI patients, once the acute phase is resolved, regardless of whether or not they have GH-deficiency (GHD).
3/29/2016 ... This first study of DBS to this target for severe TBI supports its safety and suggests potential effectiveness to improve function years after injury.
4/4/2016 ... Effective RTW interventions for patients with ABI are a combination of work-directed interventions, coaching/education and/or skills training.
4/6/2016 ... There is insufficient evidence to determine whether pharmacological treatment is effective in chronic cognitive impairment in TBI.
Treatment of severe, disabling spasticity with continuous intrathecal baclofen therapy following acquired brain injury
4/19/2016 ... The study showed encouraging long-term outcomes and safety for ITB therapy after ABI-related intractable spasticity.
4/27/2016 ... There is no evidence of efficacy for neuroleptics. Their prescription is based on emergency situation for a crisis (loxapine) but not for long-term use (EC).
5/6/2016 ... Patients undergoing hyperbaric therapy achieved significant improvement in the GCS and GOS with a lower overall mortality, suggesting its utility as a standard intensive care regimen in traumatic brain injury.
Can Cognitive Behavioral Therapy for Insomnia also treat fatigue, pain, and mood symptoms in individuals with traumatic brain injury?
5/24/2016 ... We conclude that CBT-I may provide secondary benefits for symptoms commonly experienced by individuals with TBI, especially mood disturbances.
6/3/2016 ... rTMS offers a non-invasive treatment option for MTBI-HA.
Increased risk of new-onset depression in patients with traumatic brain injury and hyperlipidemia: the important role of statin medications
6/10/2016 ... Preexisting hyperlipidemia could be an independent predictor of new-onset depression in TBI patients, and TBI patients with preexisting hyperlipidemia who were not treated with statins presented a higher risk of new-onset depression than TBI patients without hyperlipidemia.
6/13/2016 ... The case reports show promise for the treatment of sexual dysfunction after severe TBI using standard medical and sex therapy treatments.
6/13/2016 ... The case reports show promise for the treatment of sexual dysfunction after severe TBI using standard medical and sex therapy treatments.
Effects of a rapid-resisted elliptical training program on motor, cognitive and neurobehavioral functioning in adults with chronic traumatic brain injury
6/17/2016 ... There is evidence that intensive rapid-resisted training has specific positive effects on dynamic balance and more generalized effects on sleep quality in TBI.
6/28/2016 ... Individuals suffering from prolonged symptoms after TBI reported reduced mental fatigue and improved cognitive functions with long-term methylphenidate treatment.
7/19/2016 ... Findings from this exploratory RCT suggest subsymptom exacerbation aerobic training is potentially beneficial for adolescents with persistent symptoms after an mTBI.
8/2/2016 ... Treatment with the CRP for posttraumatic BPPV resulted in significant symptom resolution and improvement in perceived physical health status.
Efficacy of motivational interviewing and cognitive behavioral therapy for anxiety and depression symptoms following traumatic brain injury
8/9/2016 ...Findings suggest that modified CBT with booster sessions over extended periods may alleviate anxiety and depression following TBI.
Systematic review of traumatic brain injury and the impact of antioxidant therapy on clinical outcomes
8/12/2016 ... By incorporating antioxidant therapies into practice, clinicians can help attenuate the oxidative posttraumatic brain damage and optimize patients' recovery.
Effectiveness of direct and non-direct auditory stimulation on coma arousal after traumatic brain injury
8/15/2016 ... Auditory stimulation, in particular direct auditory stimulation, might be useful for improving the recovery of consciousness and increasing the arousal of comatose patients.
8/17/2016 ... People in recovery from moderate-to-severe TBI can, with minimal guidance, perform vigorous, community-based exercise.
A review of the neuroprotective role of vitamin D in traumatic brain injury with implications for supplementation post-concussion
8/25/2016 ... VDH supplementation cannot be recommended at this time to improve outcomes following TBI.
Effectiveness of interventions to improve occupational performance for people with psychosocial, behavioral, and emotional impairments after brain injury
9/8/2016 ...An increasing body of evidence supports specific interventions to improve occupational performance and participation for people with psychosocial, behavioral, or emotional impairments after TBI.
Effectiveness of sensory stimulation to improve arousal and alertness of people in a coma or persistent vegetative state after traumatic brain injury
9/9/2016 ... Studies provide strong evidence that multimodal sensory stimulation improves arousal and enhances clinical outcomes for people in a coma or persistent vegetative state after TBI.
9/23/2016 ...While there is currently no single pharmacological therapy that will unequivocally improve clinical outcomes after TBI, several agents have demonstrated promising clinical benefits for specific TBI patients and should be investigated further.
Pilot study of intensive exercise on endurance, advanced mobility and gait speed in adults with chronic severe acquired brain injury
10/5/2016 ...People with chronic ABI can improve endurance,
demonstrate the ability to do advanced gait and improve ambulatory status with 6 weeks of intensive exercise.
10/10/2016 ...With evidence of unsurpassed safety and
tolerability, n-3FA should be considered mainstream, conventional medicine, if conventional medicine can overcome its inherent bias against nutritional, nonpharmacologic therapies.
Goal Management Training combined with external cuing as a means to improve emotional regulation, psychological functioning, and quality of life in patients with acquired brain injury
10/12/2016 ... Findings indicated beneficial effects of GMT on emotional regulation skills in everyday life and in quality of life six months post-treatment.
10/17/2016 ... The authors suggested that EPO is beneficial for patients with TBI in terms of reducing mortality and shortening hospitalization time without increasing the risk of DVT.
10/28/2016 ... Pharmacotherapy after TBI may be associated with a reduction in depressive symptomatology.
11/9/2016 ... This is the first report of visual field expansion by strabismus facilitated by correction of ptosis.
Randomised, waiting list controlled trial of cognitive-behavioural therapy for persistent postconcussional symptoms after traumatic brain injury
11/16/2016 ... This study suggests that CBT can improve quality of life for adults
with persistent PCS and potentially reduce symptoms for some, in the context of
outpatient brain injury rehabilitation services.
12/7/2016 ... Available evidence, although weak, shows promise in this population.
12/16/2016 ... This pilot study found that spectacle treatment, specifically
directed at optimising near task visual function, significantly reduced symptoms
in 50 per cent of patients and improved reading performance in 50 per cent.
12/22/2016 ... For mild TBI, results indicate HBO2 is no better than sham treatment.
12/27/2016 ... Specific improvements in long-term mood state and short-term mood
responses following individual exercise sessions were observed in these
individuals with TBI.
1/9/2017 ... Despite limited studies in
this field, this meta-analysis indicates that CT is modestly effective in improving cognitive and functional outcomes in patients with post-acute TBI and should therefore play a more significant role in TBI rehabilitation.
A systematic review of the effect of physical exercise on cognition in stroke and traumatic brain injury patients
1/11/2017 ... The preponderance of evidence suggests a positive effect of physical exercise on global cognitive functioning, especially in the chronic stages of a brain injury.
Methylphenidate and memory and attention adaptation training for persistent cognitive symptoms after traumatic brain injury
1/23/2017 ... hese results suggest that combined treatment with
metacognitive rehabilitation (MAAT) and pharmacotherapy (MPH) can improve aspects
of attention, episodic and working memory, and executive functioning after
1/8/2015 ... Mild traumatic brain injury is an independent significant risk factor for ischemic stroke.
5/5/2015 ... There was a 6-fold increase in the rate of hemorrhagic stroke following TBI compared with the pre-TBI period.
6/20/2016 ... Selective serotonin reuptake inhibitor use was associated with an increased risk of hemorrhagic stroke.