Research Reports - Non-invasive brain stimulation for the treatment of symptoms following traumatic brain injury
Front Psychiatry. 2015 Aug 26;6:119. doi: 10.3389/fpsyt.2015.00119. eCollection
Dhaliwal SK(1), Meek BP(1), Modirrousta MM(1).
BACKGROUND: Traumatic brain injury (TBI) is a common cause of physical,
psychological, and cognitive impairment, but many current treatments for TBI are
ineffective or produce adverse side effects. Non-invasive methods of brain
stimulation could help ameliorate some common trauma-induced symptoms.
OBJECTIVE: This review summarizes instances in which repetitive Transcranial
Magnetic Stimulation (rTMS) and transcranial Direct Current Stimulation (tDCS)
have been used to treat symptoms following a TBI. A subsequent discussion
attempts to determine the value of these methods in light of their potential
METHODS: The research databases of PubMed/MEDLINE and PsycINFO were
electronically searched using terms relevant to the use of rTMS and tDCS as a
tool to decrease symptoms in the context of rehabilitation post-TBI.
RESULTS: Eight case-studies and four multi-subject reports using rTMS and six
multi--subject studies using tDCS were found. Two instances of seizure are
CONCLUSION: There is evidence that rTMS can be an effective treatment option for
some post-TBI symptoms, such as depression, tinnitus, and neglect. Although the
safety of this method remains uncertain, the use of rTMS in cases of mild TBI
without obvious structural damage may be justified. Evidence on the effectiveness
of tDCS is mixed, highlighting the need for additional investigations.