Research Reports - Trajectories and associated factors of quality of life, global outcome, and post-concussion symptoms in the first year following mild traumatic brain injury

Qual Life Res. 2015 Dec 26. [Epub ahead of print]

Chiang CC(1), Guo SE(2), Huang KC(3), Lee BO(4), Fan JY(5).

PURPOSE: To investigate the associated factors and change trajectories of quality
of life (QoL), global outcome, and post-concussion symptoms (PCS) over the first
year following mild traumatic brain injury (mTBI).
METHODS: This was a prospective longitudinal study of 100 participants with mTBI
from neurosurgical outpatient departments in Chiayi County District Hospitals in
Taiwan. The checklist of post-concussion syndromes (CPCS) was used to assess PCS
at enrollment and at 1, 3, and 12 months after mTBI; the glasgow outcome scale
extended (GOSE), the quality of life after brain injured (QOLIBRI), Chinese
version, and the Short Form 36 Health Survey (SF-36), Taiwan version, were used
to assess mTBI global outcome and QoL at 1, 3, and 12 months after mTBI.
RESULTS: Latent class growth models (LCGMs) indicated the change trajectories of
QOLIBRI, PCS SF-36, MCS SF-36, GOSE, and PCS. Classes of trajectory were
associated with age ≥40 years, unemployment at 1 month after injury, and
educational level ≤12 years. Univariate analysis revealed that employment status
at 1 month post-injury was correlated with the trajectories of QOLIBRI, PCS
SF-36, MCS SF-36, and GOSE, but not PCS.
CONCLUSIONS: Employment status was the most crucial associated factor for QoL in
individuals with mTBI at the 1-year follow-up. Future studies should explore the
benefits of employment on QoL of individuals with mTBI. 

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