Research Reports - Sex-Specific Predictors of Inpatient Rehabilitation Outcomes After Traumatic Brain Injury

Arch Phys Med Rehabil. 2016 Feb 1. pii: S0003-9993(16)00046-0. doi:
10.1016/j.apmr.2016.01.011. [Epub ahead of print]

Chan V(1), Mollayeva T(2), Ottenbacher KJ(3), Colantonio A(2).

OBJECTIVE: To identify sex-specific predictors of inpatient rehabilitation
outcomes among patients with a traumatic brain injury (TBI) from a
population-based perspective.
DESIGN: Retrospective cohort study.
SETTING: Inpatient rehabilitation.
PARTICIPANTS: Patients in inpatient rehabilitation for a TBI within 1 year of
acute care discharge between 2008/2009 and 2011/2012 (N=1730, 70% men, 30%
women).
INTERVENTIONS: None.
MAIN OUTCOME MEASURES: Inpatient rehabilitation length of stay, total FIM score,
and motor and cognitive FIM ratings at discharge.
RESULTS: Sex, as a covariate in multivariable linear regression models, was not a
significant predictor of rehabilitation outcomes. Although many of the predictors
examined were similar across men and women, sex-specific multivariable models
identified some predictors of rehabilitation outcome that are specific for men
and women; mechanism of injury (P<.0001) was a significant predictor of
functional outcome only among women, whereas comorbidities (P<.0001) was a
significant predictor for men only.
CONCLUSIONS: Predictors of outcomes after inpatient rehabilitation differed by
sex, providing evidence for a sex-specific approach in planning and resource
allocation for inpatient rehabilitation services for patients with TBI. 

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