Research Reports - Factors related to fatigue after paediatric acquired brain injury
Brain Inj. 2016 Aug 26:1-9. [Epub ahead of print]
van Markus-Doornbosch F(1), de Kloet AJ(1,)(2), Berger MA(2), Lambregts
SA(3,)(4), Wolterbeek R(5), Vliet Vlieland TP(1,)(6,)(7).
OBJECTIVE: To assess the degree of fatigue in children and youth after traumatic
and non-traumatic brain injury (TBI and NTBI) and related factors.
METHOD: Follow-up study including patients with a hospital-based diagnosis of
acquired brain injury (ABI), aged 4-20 years at onset and their parents. Parents
and children (dependent on age) completed the Paediatric Quality of Life
Inventory™ Multidimensional Fatigue Scale (PedsQL™ MFS), which measures general
fatigue (GF), sleep/rest fatigue (SRF) and cognitive fatigue (CF). Additional
assessments included the Child & Family Follow-up Survey (CFFS) and PedsQL™ 4.0
General Core Scales and sociodemographic and disease characteristics.
RESULTS: Eighty-eight parents completed the PedsQL™ MFS 24-30 months after
diagnosis, with 49/88 patients (56%) completing the child version. The median age
of the patients was 11 years (interquartile range [IQR] = 7). There were 69
patients with TBI (16% moderate/severe TBI) and 19 patients with NTBI (16%
moderate/severe NTBI). The median parent-reported and child-reported PedsQL™ MFS
Total Scale Scores were 76.5 (SD = 16.4) and 78.5 (12.9), respectively (Spearman
r = 0.450, p = 0.001). Apart from NTBI, increasing age and a single-parent
household were significantly associated with more fatigue according to the
parent-reported PedsQL™ MFS Total Score (and/or one or more sub-scale scores).
CONCLUSION: Two years after onset, in particular, the parent-reported fatigue
after NTBI was considerable. Moreover, older children and children from a
single-parent household were found to have higher fatigue levels.