Research Reports - Aripiprazole improves various cognitive and behavioral impairments after traumatic brain injury: a case report

Gen Hosp Psychiatry. 2012 Jun 13

Umene-Nakano W, Yoshimura R, Okamoto T, Hori H, Nakamura J.

Various types of cognitive and behavioral impairments occur after traumatic brain
injury. We present a case exhibiting psychotic symptoms such as irritability,
dysphoria, anxiety and insomnia with severe brain dysfunction due to a right
temporal lobe contusion incurred in a traffic accident. The patient did not
sufficiently respond to rehabilitation or treatment with any pharmacotherapy. In
the present case, aripiprazole dramatically improved the patient's symptoms and
cognitive function. We evaluated the case using the Wechsler Adult Intelligence
Scale-Revised and the Wechsler Memory Scale Revised between baseline and 5 years
later.

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